Orthopaedic Science Laboratories
 
 
The Orthopaedic Science Laboratories (OSL) broadly examines how bone responds to physical stimuli, both small and large. We use multi-disciplinary approaches to examine basic cellular signaling pathways at levels ranging from expression of specific transcription factors in response to mechanical loading (or lack thereof) to use of complex adaptive systems biology to study the integrated behavior of osteocyte/osteoblast networks. Upcoming OSL Presentations 2011 ORS Annual Meeting Bain, S.D., Rothenberg, A., Poliachik, S.L., Ausk, B.J., and Gross, T.S.,2011, “Bone loss following peripheral nerve injury in mice is rapid and profound,” ORS 2011 Annual Meeting, January 13-16, 2011, Long Beach, California. - Short Talk Ausk, B.J., Huber, P., Srinivasan, S., Bain, S.D., and Gross, T.S., 2011, “Initiation of trabecular bone resorption following transient muscle paralysis is site specific,” ORS 2011 Annual Meeting, January 13-16, 2011, Long Beach, California. - Poster Worton, L.E., Gardiner, E.M., Bain, S.D., and Gross, T.S., 2011, “Transient muscle paralysis increases the osteoclastic differentiation potential of marrow,” ORS 2011 Annual Meeting, January 13-16, 2011, Long Beach, California. - Poster 2011 ASBMR Forum on Aging and Skeletal Health Gardiner, E.M., 2011, "Role of the CNS in mediating age-related bone loss," ASBMR Forum on Aging and Skeletal Health. March 21-23, 2011, Bethesda, Maryland. Plenary Talk. In the News University of Washington Orthopedic and Sports Medicine Enews Steve Bain Brandon Auskhttp://www.orthop.washington.edu/UserFiles/File/eNews/Archive/eNews_April.pdfhttp://www.orthop.washington.edu/UserFiles/File/eNews/Archive/eNews_July.pdfshapeimage_1_link_0shapeimage_1_link_1
Introduction to the OSL