|  Home  |  Site Map  |  News  |  Contact Us  |  Helpful Links  |
From the Chairman
Clinical Specialties
Faculty at a Glance
 Alphabetical Listing
 Clinical Practitioners
 Funded Research Faculty
Training
Research
Alumni
Member's Section

HENRY OU, MD

Associate Professor

Department
Otolaryngology - Head and Neck Surgery

Specialties
Pediatric Otolaryngology

Site(s) of Practice, Maps, and Directions
Seattle Children's Hospital

Area(s) of Expertise
Ear Disease
Neck Masses
Hearing Loss
Cochlear Implantation
Endoscopic Sinus Surgery

Education
MD--Washington University School of Medicine, St. Louis, MO

Postgraduate Training
Fellowship--Pediatric Otolaryngology--University of Washington, Children’s Hospital and Regional Medical Center
Internship--General Surgery, University of Washington
Residency--Otolaryngology-Head and Neck Surgery, University of Washington

Board Certifications
American Board of Otolaryngology, 2005

Licensure
State of Washington

Most Significant Articles and Abstracts

Patents

  • Compounds that protect against sensory hair cell death. U.S. Patent No. US 8,232,314 B2.  July 31, 2012.

Recent Presentations:

  • Ou HC, Raible DW, Rubel EW: Using the zebrafish lateral line to screen an FDA library for compounds that protect hair cells. Presented at 2007 Association for Research in Otolaryngology Midwinter Meeting.
  • Choi H, Rubel EW, Raible DW, Simon J, Ou H: The role of oxidative stress and antioxidants in zebrafish lateral line hair cell damage.  Presented at the Midwinter Meeting of the Association for Research in Otolaryngology, 2011.
  • Hirose Y, Rubel EW, Raible DW, Simon J, Ou H: Assessing the synergistic ototoxicity of anti-cancer drug combinations using the zebrafish lateral line.  Presented at the Midwinter Meeting of the Association for Research in Otolaryngology, 2011.
  • Keating S, Rubel EW, Raible DW, Simon J, Ou H: Quinoline derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line.  Presented at the Midwinter Meeting of the Association for Research in Otolaryngology, 2011.
  • Wu P, Esterberg R, Ou H: Hydrogen peroxide production can be measured in lateral line hair cells using HyPer [Tg(myosin6b:HyPer)] expressing zebrafish. Presented at the Midwinter Meeting of the Association for Research in Otolaryngology, 2013.
  • Thomas A, Wu P, Raible D, Rubel E, Simon J, Ou H: Small molecule inhibitors of cisplatin-induced hair cell death: Results of a 10,000 compound screen in the zebrafish lateral line. Presented at the Midwinter Meeting of the Association for Research in Otolaryngology, 2013.
  • Thomas A, Wu P, Ou H: Copper-induced hair cell death in the zebrafish lateral line requires functional mechanotransduction.  Presented at the Midwinter Meeting of the Association for Research in Otolaryngology, 2013.

Research Support:

Evaluation of candidate otoprotective compounds in the mouse utricle
Principal Investigator, National Organization for Hearing Research Foundation (NOHR) Grant

Evaluation of candidate otoprotective compounds in the mouse utricle
Principal Investigator, University of Washington Royalty Research Fund (RRF) Grant

Development of a standardized scale for ototoxicity
Principal Investigator, American Society of Pediatric Otolaryngology Research Grant

As with many medical diseases, prevention of hearing loss may ultimately prove to be more effective than treatment. I am interested in developing strategies to halt hearing loss in its early stages by preventing the death of hair cells in the inner ear. My research thus revolves around understanding mechanisms of hair cell injury, and developing medical treatments for the prevention of ototoxic injury.

Top of page

 
 
 
 
   
 
 
   
     

 
   
Site by Publication Services