Gerard Cangelosi, Ph.D.
Assistant Professor, Pathobiology
(University of California, Davis, 1983)
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Email: cangelos@u.washington.edu |
Pathogens of the genus Mycobacterium cause tuberculosis, leprosy, MAC
(M. avium complex) disease, and other significant diseases of humans. Our
research is aimed at understanding the characteristics of the pathogens that
facilitate exposure, infection, persistence, and drug resistance. Current
research includes 1) mutational and functional genomic analysis
of mycobacterial phase variation phenomena that affect virulence, drug
resistance, and biofilm formation; 2) application of genomic techniques
to improve our understanding of routes of MAC and TB acquisition; and 3) improved
methods for detecting mycobacterial pathogens in clinical and environmental
samples.