PBIO SEMINAR SERIES

Tyrosination: an enigmatic covalent modification of tubulin linked to tumor growth and to neuronal organization

Wednesday - February 07, 2007
06-07 Seminar Series

Didier Job MD
Director, Cytoskeleton Laboratory INSERM-CEA, Grenoble Institute of Neurosciences
Speaker's website

Host: Wordeman

My main interests have concerned physico-chemical aspects of tubulin assembly and of microtubule self-organization, microtubule regulation by associated proteins (principally STOP proteins) and covalent modifications of tubulin. We have used biochemical approaches as well as genetic systems such as yeast or transgenic mice, to decipher the function of microtubule effectors and evaluate their potential interest in pathology.