PBIO SEMINAR SERIES

Control of the duration of inhibitory signals in the auditory system

Wednesday - April 30, 2008
07-08 SEMINAR SERIES

Larry Trussell
Professor  Oregon Hearing Research Center / Vollum Institute - OHSU
Speaker's website

Host: Andres Barria

The preserving and encoding the relative timing of electrical signals is a key element of auditory processing, and depends greatly on synaptic inhibition mediated by glycine and GABA. In exploring what determines the lifespan of inhibitory postsynaptic signals, we have identified factors intrinsic to receptors, as well as major roles for transmitter diffusion and control of vesicle content