Physiology and Biophysics

Seminars

Sep
24
Tue
2019
“Linking Metabolism to the Extracellular Matrix” – Presented by Center for Cardiovascular Biology and Mitochondria and Metabolism Center @ South Lake Union
Sep 24 @ 9:00 am – 10:00 am
Steven P. Jones, PhD, Professor of Medicine and University Scholar, University of Louisville, School of Medicine, Director, Diabetes and Obesity; Center, Division of Environmental Medicine
Sep
25
Wed
2019
“Neuronal Substrates for Auditory Perception and Decision Making” – Presented by Department of Otolaryngology – Head and Neck Surgery and Virginia Merrill Bloedel Hearing Research Center @ Center on Human Development and Disability (CHDD)
Sep 25 @ 10:00 am – 11:00 am
Yale E. Cohen, PhD, Professor Otolaryngology: Head and Neck Surgery Director, Hearing Sciences Center and The Auditory Research Laboratory University of Pennsylvania School of Medicine
STROKE: “An Update on Endovascular Treatments in Acute Ischemic Stroke” – Presented by CME Neurology Lecture Series @ Harborview Medical Center
Sep 25 @ 12:00 pm – 1:00 pm
Sep
26
Thu
2019
“HIV and Reproductive Health: Navigating the Space Between a Hard Place and a Rock” – Presented by Department of Medicine – 2019 Chief of Medicine Scholars @ Health Sciences Building
Sep 26 @ 8:00 am – 9:00 am
Rena Patel, MD, Assistant Professor Division of Allergy and Infectious Diseases Department of Medicine, University of Washington
“Phenotyping Sepsis Induced Acute Kidney Injury” – Presented by Department of Medicine Grand Rounds – 2019 Chief of Medicine Scholars @ Health Sciences Building
Sep 26 @ 8:00 am – 9:00 am
Pavan Bhatraju, MD, MSc, Assistant Professor Division of Pulmonary, Critical Care and Sleep Medicine Department of Medicine, University of Washington
“The Spectrum of Thrombotic Microangiopathies: from Autoimmune TTP to Transplant-Associated TMA” – Presented by Department of Medicine – 2019 Chief of Medicine Scholars @ Health Sciences Building
Sep 26 @ 8:00 am – 9:00 am
Ang Li, MD, Acting Instructor Division of Hermatology, Department of Medicine University of Washington
PBIO seminar series: [no speaker scheduled]
Sep 26 @ 9:30 am – 10:30 am
“A Multi-Scale Perspective on Vagus Nerve and Brain Development: From Gut to Glia to Non-Invasive Monitoring and Manipulation of Brain-Body Communication” – Presented by Department of Neurology Grand Rounds @ Health Sciences Building
Sep 26 @ 4:30 pm – 5:30 pm
Martin Frasch, MD, PhD, Research Assistant Professor Department of Obstetrics and Gynecology Research Affiliate, Center on Human Development and Disability, University of Washington
Oct
3
Thu
2019
PBIO seminar series: [no speaker scheduled]
Oct 3 @ 9:30 am – 10:30 am
Oct
10
Thu
2019
PBIO seminar series: [no speaker scheduled]
Oct 10 @ 9:30 am – 10:30 am
Oct
17
Thu
2019
PBIO seminar series: [no speaker scheduled]
Oct 17 @ 9:30 am – 10:30 am
Oct
24
Thu
2019
PBIO seminar series: [no speaker scheduled]
Oct 24 @ 9:30 am – 10:30 am
Oct
29
Tue
2019
2019 Lamport Lecture: Brian Kobilka @ Hogness Auditorium
Oct 29 @ 4:00 pm – 5:00 pm
Structural insights into the dynamic process of G protein coupled receptor activation Brian Kobilka, MD Professor Department of Molecular and Cellular Physiology Stanford University School of Medicine Hélène Irwin Fagan Chair in Cardiology host: Stan Froehner abstract: G protein coupled receptors (GPCRs) conduct the majority of transmembrane responses to hormones and neurotransmitters, and mediate the senses of sight, smell and taste. The b2 adrenergic receptor (b2AR), the M2 muscarinic receptor and the mu-opioid receptor are prototypical Family A GPCRs. We have obtained three-dimensional structures of these receptors in inactive and active conformations, as well as a structure of the b2AR in complex with the G protein Gs. Comparison of these structures provides insights into common mechanisms for propagation of conformational changes from the agonist binding pocket to the G protein coupling interface. Crystal structures of inactive and active states may give the impression that GPCRs behave as simple two-state systems. However, cellular signaling assays reveal that many GPCRs signal through more than one G protein isoform, and through G protein independent pathways. This complex functional behavior provides evidence for the existence of multiple functionally distinct conformational states. We have used fluorescence, EPR and NMR spectroscopy to study the dynamic properties of several GPCRs. I will discuss what we these studies have taught us about allosteric regulation of GPCR structure by G proteins and ligands.    
Nov
7
Thu
2019
PBIO seminar series: [no speaker scheduled]
Nov 7 @ 9:30 am – 10:30 am
Nov
14
Thu
2019
PBIO seminar series: [no speaker scheduled]
Nov 14 @ 9:30 am – 10:30 am
Nov
21
Thu
2019
PBIO seminar series: [no speaker scheduled]
Nov 21 @ 9:30 am – 10:30 am
Dec
5
Thu
2019
PBIO seminar series: Elena Gracheva
Dec 5 @ 9:30 am – 10:30 am
Elena Gracheva, PhD Associate Professor of Physiology and of Neuroscience Yale   host: John Tuthill
Jan
9
Thu
2020
PBIO seminar series: [no speaker scheduled]
Jan 9 @ 9:30 am – 10:30 am
Jan
16
Thu
2020
PBIO seminar series: [no speaker scheduled]
Jan 16 @ 9:30 am – 10:30 am
Jan
23
Thu
2020
PBIO seminar series: [no speaker scheduled]
Jan 23 @ 9:30 am – 10:30 am
Jan
30
Thu
2020
PBIO seminar series: [no speaker scheduled]
Jan 30 @ 9:30 am – 10:30 am
Feb
6
Thu
2020
PBIO seminar series: Bita Moghaddam
Feb 6 @ 9:30 am – 10:30 am
Feb
13
Thu
2020
reserved for Neuro Grad Program recruitment
Feb 13 @ 9:30 am – 10:30 am
Feb
20
Thu
2020
PBIO seminar series: [no speaker scheduled]
Feb 20 @ 9:30 am – 10:30 am
Feb
27
Thu
2020
PBIO seminar series: [no speaker scheduled]
Feb 27 @ 9:30 am – 10:30 am
Mar
5
Thu
2020
PBIO seminar series: [no speaker scheduled]
Mar 5 @ 9:30 am – 10:30 am
Mar
12
Thu
2020
PBIO seminar series: [no speaker scheduled]
Mar 12 @ 9:30 am – 10:30 am
Apr
2
Thu
2020
hold for Hille Lecture
Apr 2 @ 9:30 am – 10:30 am
Apr
9
Thu
2020
hold for Hille Lecture
Apr 9 @ 9:30 am – 10:30 am
Apr
16
Thu
2020
hold for Hille Lecture
Apr 16 @ 9:30 am – 10:30 am