Physiology and Biophysics

Seminars

May
10
Thu
2018
2018 Crill Lecture – J. Anthony Movshon @ HSB T-639
May 10 @ 2:00 pm – 3:00 pm
“Elements of visual form perception” J. Anthony Movshon, PhD

Professor, Department of Ophthalmology

Professor, Department of Neuroscience and Physiology

Thursday, May 10, 2018 2:00 p.m. T-639 HSB
May
17
Thu
2018
PBIO Seminar Series: Brent Doiron, Ph.D. @ HSB G-328
May 17 @ 9:30 am – 10:30 am

New Cortex.  Who dis(inhibition)?

  Brent Doiron, PhD Professor Department of Mathematics University of Pittsburgh host: Adrienne Fairhall seminar abstract: New Cortex.  Who dis(inhibition)?   It is now clear that the inhibitory circuitry within cortical networks is very complex, with multiple cell types interacting with one another and pyramidal neurons in complicated and cell specific ways.  The theoretical community has been slow to adapt to this new circuit reality, and much of our results are obtained from analysis of simpler recurrent excitatory-inhibitory circuits. Two often cited functional roles of inhibition is to: 1) stabilize the dynamics of recurrently coupled excitatory networks, and 2) enact gain control of excitatory neuron responses to a driving stimulus.  In classic excitatory-inhibitory networks mechanisms that place the network in a high gain state necessarily flirt with network instability.  We analyze how recurrent networks of pyramidal neurons (PN), parvalbumin-expressing (PV), somatostatin-expressing (SOM), and vasoactive intestinal polypeptide-expressing (VIP) interneurons compartmentalize stability and gain control through distinct inhibitory and disinhibitory pathways.  This permits a disassociation of stability and gain control in the circuit.  We further show how PC to SOM connections can be crucial in state dependent gain amplification with a simultaneous decrease of shared variability (noise correlations).  In sum, by expanding the complexity of inhibitory architecture cortical circuits can navigate distinct functional roles of inhibition through a “division of labor” with the inhibitory circuit.  This imparts a robustness to the functional operations of the circuit that is absent in the often fine-tuned reduced excitatory-inhibitory framework.
May
24
Thu
2018
PBIO Seminar Series: Ariel Rokem @ HSB G-328
May 24 @ 9:30 am – 10:30 am
seminar: T.B.A. Ariel Rokem, PhD Senior Data Scientist eScience Institute, University of Washington host: Fairhall
May
31
Thu
2018
PBIO Seminar Series: Nicholas Whitehead @ HSB G-328
May 31 @ 9:30 am – 10:30 am
Simvastatin: unexpected or logical therapy for muscular dystrophy? Nicholas P Whitehead, Ph.D. University of Washington host: Stanley C. Froehner
Jun
7
Thu
2018
PBIO Seminar Series: Amy Bastian @ HSB G-328
Jun 7 @ 9:30 am – 10:30 am

Learning and Relearning Movement

Human motor learning depends on a suite of brain mechanisms that are driven by different signals and operate on timescales ranging from minutes to years. Understanding these processes requires identifying how new movement patterns are normally acquired, retained, and generalized, as well as the effects of distinct brain lesions. The lecture focuses on normal and abnormal motor learning and how we can use this information to improve rehabilitation for individuals with neurological damage Amy Bastian, Ph.D. Professor of Neuroscience Johns Hopkins University Host: John Tuthill
Aug
8
Wed
2018
“Update on the management of acute ischemic stroke” – Presented by UW CME Neurology Lecture Series @ Harborview Medical Center
Aug 8 @ 12:00 pm – 1:00 pm
David L. Tirschwell, MD Attending, Neurology University of Washington
Aug
9
Thu
2018
“Three Things to Discuss on Parkinson’s Disease” – Presented by Department of Neurology Grand Rounds @ Health Sciences Building
Aug 9 @ 4:30 pm – 5:30 pm
Ali Samii, MD, Professor Department of Neurology Co-Director, Movement Disorder Fellowship University of Washington
Aug
13
Mon
2018
“The Role of RNA-Binding Protein, Muscleblind-Like 1, in Cardiac Wound Healing and Remodeling” – Doctoral Dissertation @ South Lake Union
Aug 13 @ 3:00 pm – 4:00 pm
Christina J. Jones Department of Pharmacology Advisor: Dr. Randall Moon
“Evolution of cognition and language: Perspectives from human and nonhuman primate neural systems” – Presented by Department of Physiology & Biophysics @ Health Sciences Building
Aug 13 @ 3:30 pm – 4:30 pm
Professor Christopher I. Petkov Laboratory of Comparative Neuropsychology Newcastle University, U.K.
Aug
16
Thu
2018
“Cortical Circuits for Sensory Processing and Behavior” – Presented by Department of Physiology & Biophysics @ Health Sciences Building
Aug 16 @ 10:00 am – 11:00 am
David Margolis, PhD Department of Cell Biology & Neuroscience Rutgers University New Brunswick, NJ
“Update on Spinal Cord Emergencies” – Presented by Department of Neurology Grand Rounds @ Health Sciences Building
Aug 16 @ 4:30 pm – 5:30 pm
Randall M. Chesnut, MD, FCCM, FACS, FAANS Integra Endowed Professor of Neurotrauma Department of Neurological Surgery and Orthopaedic Surgery University of Washington
Aug
20
Mon
2018
“Deciphering the Gene Regulatory Interactions Driving Immune Evasion in Cancer” – Faculty Candidate Seminar – Presented by Department of Immunology @ South Lake Union
Aug 20 @ 3:30 pm – 4:30 pm
Paola Betancur, Ph.D. Postdoctoral Fellow/Instructor Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine
Aug
22
Wed
2018
“A Case of Progressive Weakness and Diplopia” – Presented by UW CME Neurology Lecture Series @ Harborview Medical Center
Aug 22 @ 12:00 pm – 1:00 pm
David Ivanick, MD Resident, Neurology University of Washington
Aug
23
Thu
2018
“Human pluripotent stem cell models of heart development and disease” – Presented by Institute for Stem Cell & Regenerative Medicine @ South Lake Union
Aug 23 @ 12:00 pm – 1:00 pm
David A. Elliott, PhD Tem Leader; Cardiac Regeneration Murdoch Children’s Research Institute
“Toxins and the Nervous System” – Presented by Department of Neurology Grand Rounds @ Health Sciences Building
Aug 23 @ 4:30 pm – 5:30 pm
Lucio G. Costa, Professor Department of Env. and Occ. Health Sciences University of Washington
Aug
24
Fri
2018
“Responsible Management of Data: Lessons from a Statewide Biobank” – 2018 Biomedical Research Integrity Program @ Health Sciences Building, Hogness Auditorium
Aug 24 @ 4:00 pm – 5:00 pm
Elizabeth Boyd, PhD Vice President for Research Administration Fred Hutchinson Cancer Research Center
Aug
29
Wed
2018
“Surgical Treatments in pseudotumor cerebri” – Presented by UW CME Neurology Lecture Series @ Harborview Medical Center
Aug 29 @ 12:00 pm – 1:00 pm
Michael Levitt, MD, Assistant Professor Neurological Surgery, Radiology and Mechanical Engineering University of Washington
“Resident memory T cells” – Presented by Department of Immunology – Faculty Candidate Seminar @ South Lake Union
Aug 29 @ 3:30 pm – 4:30 pm
Lalit Beura, PhD, Post-doctoral Associate Department of Microbiology & Immunology University of Minnesota
Aug
30
Thu
2018
“TBA” – Presented by Department of Neurology Grand Rounds @ Health Sciences Building
Aug 30 @ 4:30 pm – 5:30 pm
Thomas Grabowski, Professor, Radiology and Neurology Director, Memory and Brain Wellness Center & Integrated Brain Imaging Center University of Washington
Sep
4
Tue
2018
“Development of an electronic health record registry to support implementation of collaborative care for perinatal depression” – Presented by Department of Family Medicine @ Roosevelt 1 Building
Sep 4 @ 12:00 pm – 1:00 pm
Ian M Bennett, MD, PhD, Professor Family Medicine Psychiatry & Behavioral Sciences
“A journey into Influenza Antigenic Space Using Systems Serology” – Presented by Fred Hutch VIDD Scientific Seminar Series @ Fred Hutchinson Cancer Research Center
Sep 4 @ 3:00 pm – 4:00 pm
Tomer Hertz, PhD Senior Lecturer (Assistant Professor) Department of Microbiology, Immunology & Genetics Faculty of Health Sciences Ben Gurion University of Negev
Sep
5
Wed
2018
“The good, the bad and the ugly of blood pressure and stroke prevention” – UW CME Neurology Lecture Series @ Harborview Medical Center
Sep 5 @ 12:30 pm – 1:30 pm
Sandeep Khot, MD, Associate Professor Department of Neurology University of Washington
Sep
6
Thu
2018
“Advances in Lung Cancer Treatment” – Presented by Department of Medicine Grand Rounds @ Health Sciences Building
Sep 6 @ 8:00 am – 9:00 am
Keith Eaton, MD, PhD, Professor Division of Oncology Department of Medicine, UW
“Some ‘Newish’ Things in Clinically Relevant Neuroscience” @ Health Sciences Building
Sep 6 @ 4:30 pm – 5:30 pm
Bruce R. Ransom, MD, PhD, Professor and Chairman Department of Neurology, Adjunct Professor, Department of Physiology & Biophysics, UW
Sep
7
Fri
2018
“TB Systems Biology: Tools to Take On A Killer” – Presented by UW School of Medicine – Chair Candidate Research Seminar @ Health Sciences Building
Sep 7 @ 12:00 pm – 1:00 pm
David R. Sherman, Ph.D., Associate Director and Professor, Center for Infectious Disease Research Affiliate Professor of Global Health in the UW Schools of Medicine and Public Health
Sep
10
Mon
2018
“MRI, microCT, or both? Exploiting the full potential of the Radiology toolbox for lung research” – Presented by Department of Radiology @ Health Sciences Building
Sep 10 @ 1:00 pm – 2:00 pm
Greetje Vande Velde, <ScEng, PhD Assistant Professor in Imaging and Pathology The KU Leuven (University of Leuven)
“Defending Scientific Integrity in a Post-Truth Era: Lessons from Canada’s ‘War on Science'” @ Hogness Auditorium, Health Sciences Building
Sep 10 @ 4:00 pm – 5:00 pm
Wendy Palen, PhD, Associate Professor Department of Biological Sciences Simon Frasier University
Sep
11
Tue
2018
“FlowJo Basic and Advances software tutorials” – Presented by Cell Analysis Facility Flow and Imaging Cytometry Core Lab @ South Lake Union
Sep 11 @ 11:00 am – 12:00 pm
Jack Panopoulos, Ph.D. Applicatin Scientist FlowJo, LLC
“FlowJo Basic and Advanced software tutorials” – Advanced FlowJo High Dimensionality tools – Presented by Cell Analysis Facility @ South Lake Union
Sep 11 @ 1:00 pm – 2:00 pm
Jack Panopoulos, Ph.D. Application Scientist FlowJo, LLC
Sep
12
Wed
2018
“Lymphocyte Differentiation and Activation: A View from Regulomes” – Presented by Department of Immunology Faculty Candidate Seminar @ South Lake Union
Sep 12 @ 3:30 pm – 4:30 pm
Han-Yu Shih, Ph.D, Postdoctoral Fellow National institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH)