John McGuire, M.D.

Assistant Professor of Pediatrics and Anesthesiology, University of Washington, Seattle Washington

Pediatric Intensive Care, Physician, Seattle Children's Hospital, Seattle, Washington

1993 MD

Northwestern University, Evanston, IL

Memorial Hospital, Northwestern University Department of Pediatrics, Chicago, IL

Resident, Pediatrics

Children's Memorial Hospital and Northwestern University Medical School, Chicago, IL

Fellow, Pediatric Critical Care Medicine

• American Thoracic Society

• American Society for Matrix Biology

1. Matrilysin in Lung Epithelial Cell Migration, NIH/NHLBI-Mentored Clinical Scientist Development Award, 2003 - 2008, K08 HL068780-01

2. Mechanisms in the Remodeling of Lung Structure, NIH-NHLBI-Program Project Grant, 2003 - 2008

3. NIH Extramural Loan Repayment Program for Pediatric Research, 2003 - 2007

4. Arnold Lee Smith Endowed Professorship for Research Faculty Development, 2006 - 2008

1. McGuire, J.K., Li, Q.L. and Parks, W.C. Matrilysin mediates E-cadherin ectodomain shedding in injured lung epithelium. Am J Pathol 2003: 162:1831-1843.

2. Surendran, K., Simon, T.C., Liapis, H., and McGuire, J.K. Matrilysin (MMP-7) expression in renal tubular damage: association with Wnt-4. Kidney Int June 2004: 65:2212-2222.

3. Thill, P.J., McGuire, J.K., Baden, H.P., Green, T.P. and Checchia, P.A. Non-invasive positive pressure ventilation in children with lower airways obstruction. Ped Crit Care Med 5:337-342, 2004.

4. Checchia, P.A., McGuire, J.K., Morrow, S., Daher, N., Huddleston, C. and Levy, F. A risk assessment scoring system predicts survival following the Norwood procedure. Pediatr Cardiol 27: 62-66, 2006.

5. Jain, S., Suarez, A.A., McGuire, J.K., Watson, M. and Liapis, H. Altered patterns of gene expression associated with congenital renal dysplasia. Pediatric Nephrology. December 2006. Submitted.

6. Swee, M.H., Wilson, C.L., McGuire, J.K. and Parks, W.C. Matrilysin (MMP-7) is Essential for Rapid Repair and Neutrophil Influx in Experimental Colitis. Gastroenterology February, 2007 Submitted.