Kenneth A. Schenkman, M.D., Ph.D.

Dr. Schenkman is internationally-known in bio-engineering and has several patents related to optical spectroscopy for assessing tissue oxygenation and mitochondrial function. He is an active critical care clinician, and has a funded laboratory with a focus on translational research at the interface between critical care medicine and bioengineering.In 1999 he developed and patented an analytic method for determining intracellular muscle oxygenation using reflectance optical spectroscopy.
Current Position
  • Associate Professor of Pediatrics and Anesthesiology, University of Washington, Seattle, Washington
    Adjunct Associate Professor, Department of Bioengineering, University of Washington School of Medicine, Seattle, Washington
  • Pediatric Intensive Care, Medical Director, Seattle Children's Hospital, Seattle, Washington
Education
1986  MD Indiana University School of Medicine, Indianapolis, IN
1996  Ph.D. Bioengineering, University of Washington Center for Bioengineering, Seattle, WA
Postgraduate Training

1986 - 89

Children's Hospital of Pittsburgh, University of Pittsburgh, School of Medicine, Pittsburgh, PA -- Intern and Resident, Pediatrics

1989 - 90

Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA -- Chief Resident, Pediatrics

1991 - 95

Children's Hospital and Medical Center, University of Washington School of Medicine, Seattle, WA -- Fellow, Pediatrics Critical Care Medicine

1994 - 95

Children's Hospital and Medical Center, University of Washington School of Medicine, Seattle, WA -- Senior Fellowship, Pediatric Critical Care Medicine

Board Certification
1989 Diplomate, American Board of Pediatrics
1996 Diplomate, Sub-board of Pediatric Critical Care Medicine
Professional Society Memberships
  • Society of Critical Care Medicine

  • American Academy of Pediatrics

  • American Association for the Advancement of Science

  • Society for Pediatric Research

  • Institute Institute of Electrical and Electronics Engineers for Electrical and Electric Engineering

  • American Physiological Society

  • American Heart Association Council on Cardiopulmonary and Critical Care

Research

Dr. Schenkman and his research team investigate cardiac and skeletal muscle intracellular oxygenation and mitochondrial function in response to hypoxis hypoxia and the application off of near-infraredoptical spectroscopy for non-invasive monitoring of muscle and cerebral oxygenation and mitochondrial function in the clinical setting.

Selected Publications

  1. Marcinek, DJ, Schenkman KA, Ciesielski WA, and Conley KE. Mitochondrial coupling in vivo in mouse skeletal muscle. Am J Physiol Cell Physiol, 286:C457-463, 2004.

  2. Ciesielski WA, Arakaki LSL, and Schenkman KA. Temperature and pH effects on myoglobin optical absorbance spectra. Proceedings of the SPIE International Symposium on Biomedical Optics. 5702-27(4), 2005.

  3. Ejike JC, Arakaki LSL, Beard DA, Ciesielski WA, Feigl EO, and Schenkman KA. Myocardial oxygenation and adenosine release in isolated guinea pig hearts during changes in contractility. Am J Physiol Heart Circ Physiol, 288: H2062-H2067, 2005.

Patents
  1. Arakaki LSL, Burns DH, Feigl EO, Kushmerick M, Marble DR, and Schenkman KA:  Real-time in vivo measurement of myoglobin oxygen saturation. United States Patent #5,931,779: U.S. Patent & Trademark Office, Issued August 3, 1999.

  2. Schenkman KA, Arakaki LSL, and Ciesielski WA:  Optical measure of mitochondrial function in blood-perfused tissue.  United States Patent applied for, May 11, 2006.

  3. Marcinek DJ, Conley KE, and Schenkman KA:  Method and system for determining the contribution of  hemoglobin and myoglobin to in vivo optical spectra.  United States Patent applied for, August 3, 2006.

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