Assistant Professor of Pharmaceutics
E-Mail: ni2@u.washington.edu

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Research Interests:

Drug diposition and drug safety during pregnancy; Expression of P450 enzymes during pregnancy; Role of P450 enzymes in fetal development;
Pharmacokinetic modeling and molecular mechanisms of drug-drug interactions

Biography:

Dr Isoherranen received her bachelor's degree in chemistry and her master's degree in Analytical Chemistry in 1998 from the University of Helsinki, Finland. She obtained a PhD from the Hebrew University of Jerusalem in 2003 and continued her training as a post-doctoral fellow with Ken Thummel at the University of Washington. She joined the Department of Pharmaceutics as an Acting Assistant Professor on November 2004.

Research in Dr Isoherranen's lab focuses on characterization of the mechanisms that contribute to changes in drug disposition during pregnancy. The research also includes evaluation of drug safety during pregnancy and the role of P450 enzymes in teratogenicity and fetal development. In addition, Dr Isoherranen's lab is conducting research on the molecular mechanisms of enzyme inhibition and the in vitro to in vivo predictions of enzyme inhibition.