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Education
PhD in Pharmaceutics, State University of New
York at Buffalo
Research Interests
- in vivo expression regulation and function
of cytochrome P450 enzymes as they relate to intestinal and hepatic
first-pass drug metabolism
- drug transport across the blood-brain and blood-spinal
cord barrier and cellular compartmentation within the brain
- pharmacokinetics and pharmacodynamics of neuroactive
agents, in particular anticonvulsants and opioid analgesics.
Courses Taught
- Pceut 501: Advanced Pharmacokinetics I
- Pceut 503: Drug Transport & Delivery
- Pceut 506: Pharmacokinetic Principles
- Pceut 510: Pharmacokinetics of Drug Interactions
Experience
Dr. Shen is a Member in the Clinical Research
Division at Fred Hutchinson Cancer Research Center, where he directs
the a pain pharmacology research group. He held faculty appointments
at the University of Kansas Medical Center and State University
of New York at Buffalo prior to his joining the faculty at the University
of Washington in 1984.
Activities
Dr. Shen is a Fellow of the American Association
of Pharmaceutical Scientists (AAPS), and a member of several other
scientific societies, including American Society of Pharmacology
and Experimental Therapeutics (ASPET), American Society of Clinical
Pharmacology and Therapeutics (ASCPT), American Society of Pain
(APS) and International Association for the Study of Pain (IASP).
He is on the editorial board of Journal of Pharmaceutical Sciences,
AAPS Journal and Pharmaceutical Research. He has served as advisor
or consultant to governmental agencies (e.g. National Institutes
of Health, Food and Drug Administration) and drug industry.
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Professor, Department of Pharmacy
and Pharmaceutics
Chair, Department of Pharmacy
(206) 685-2920
ds@u.washington.edu
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