Research

Matthew Keifer, MD, MPH

Professor, UW Departments of Medicine and Environmental & Occupational Health Sciences, PNASH Center Prevention and Intervention Core Leader

Pacific Northwest Agricultural Safety and Health Center
Department of Environmental and Occupational Health Sciences
Box 357234
Seattle, WA 98195-7234


Contact: (206) 616-1958, (800) 330-0827, pnash@u.washington.edu

 

Education

1977 BA University of Notre Dame (Anthropology)
1978 University Este School of Medicine
1982 MD University of Illinois School of Medicine (Medicine)
1989 MPH University of Washington (Public Health)

Dr. Keifer is currently the Prevention and Intervention Core Leader of the Pacific Northwest Agricultural Safety and Health Center. His work with the Center has included a skin disease prevention program for farm workers and orchard owners, prevention of ladder injuries among orchard workers, and survey of data sources in the region.

He is an internist and occupational medical specialist. He practices and teaches occupational and internal medicine at the Harborview Medical Center, one of the four primary hospitals in the University of Washington medical system. He regularly acts as an attending physician at the Harborview Occupational and Environmental Medicine Program and attends on general medicine wards one full month per year. His fluency in Spanish has allowed him to establish and conduct a monthly occupational medicine clinic at the Yakima Valley Farm Workers Clinic in Toppenish, Washington under the auspices of the Chemically Related Illness Center of Excellence headquartered at Harborview Medical Center.

Dr. Keifer came to the University of Washington in 1992 after serving two years in Nicaragua as a consulting epidemiologist for the Nicaraguan Ministry of Health with support from the CARE International Safe Use Pesticide Program. His masters level research focused on methods for assessing underreporting to a pesticide poisoning registry, and other research during and since has examined the neurobehavioral and neurological effects of organophosphate pesticide poisoning exposure. He has continued to pursue research in health effects of pesticides and is currently the Director of the Fogarty International Scholars program.

For more information regarding Dr. Keifer, please visit his faculty page.

Selected Publications

Hofmann JN, Carden A, Fenske RA, Ruark HE, Keifer MC. Evaluation of a clinic-based cholinesterase test kit for the Washington State Cholinesterase Monitoring Program. Am J Ind Med. 2008 Jul; 51(7): 532-8. PMID: 18459125

Crowe JL, Keifer MC, Salazar MK. Striving to provide opportunities for farm worker community participation in research. J Agric Saf Health. 2008 Apr;14(2):205-19. PMID: 18524285.

Phung DT, Nguyen HT, Mock C, Keifer M. Occupational injuries reported in a population-based injury survey in Vietnam. Int J Occup Environ Health. 2008 Jan-Mar;14(1): 35-44. PMID: 18320730

Keifer MC, Firestone J. Neurotoxicity of pesticides. J Agromedicine. 2007 Dec;(1):17-25. PMID: 18032333

Thepaksorn P, Daniell WE, Padungtod C, Keifer MC. Occupational accidents and injuries in Thailand. Int J Occup Environ Health. 2007 Jul-Sep;13(3):290-4. PMID: 17915543

McCauley LA, Anger WK, Keifer MC, Langley R, Robson MG, Rohlman D. Free in PMC Studying health outcomes in farmworker populations exposed to pesticides. Environ Health Perspect. 2006 Jun;114(6):953-60. Review.PMID: 16760000

Hofmann J, Snyder K, Keifer M. A descriptive study of workers' compensation claims in Washington State orchards. Occup Med (Lond). 2006 Jun;56(4):251-7. Epub 2006 Apr 20.
PMID: 16627546

Weyrauch KF, Boiko PE, Keifer M. Building informed consent for cholinesterase monitoring among pesticide handlers in Washington State. Am J Ind Med. 2005 Sep;48(3):175-81. PMID: 16094612

Salazar MK, Keifer M, Negrete M, Estrada F, Synder K.  Occupational risk among orchard workers: a descriptive study. Fam Community Health. 2005 Jul-Sep;28(3):239-52. PMID: 15958882

Thetkathuek A, Keifer M, Fungladda W, Kaewkungwal J, Padungtod C, Wilson B, Mankhetkorn S. Spectrophotometric determination of plasma and red blood cell cholinesterase activity of 53 fruit farm workers pre- and post-exposed chlorpyrifos for one fruit crop. Chem Pharm Bull (Tokyo). 2005 Apr;53(4):422-4. PMID: 15802843

Miranda J, McConnell R, Wesseling C, Cuadra R, Delgado E, Torres E, Keifer MC, and Lundberg I. Muscular strength and vibration thresholds during two years after acute poisoning with organophosphate insecticides. Occup Environ Med. 2004 January; 61(1): e4. PMCID: PMC1757809

Keifer MC, Effectiveness of interventions in reducing pesticide overexposure and poisonings. Am J Prev Med 18:80-89 2000

McConnell R, Delgad-Tellez E, Cuadra R, Torres E, Keifer MC, Almendarez J, Miranda J, El-Fawal H, Wolff M, Simpson D, Lundberg I. Organophosphate neuropathy due to methamidophos: biochemical and neurophysiological markers. Arch Toxicol 73:296-300 1999

Engel LS, Keifer MC, Checkoway H, Robinson LR, Vaughan TL. Neurophysiological function in farm workers exposed to organophosphate pesticides. Arch Environ Health 53(1):7-13 1998.

Keifer MC, The clinical laboratory in the diagnosis of overexposure to agrochemicals. Lab Med Vol 29 No 11:689-695 1998

Zahm SH, Blair A, and the Farm Workers Epidemiology Research Group (Keifer M, member). Cancer feasibility studies among migrant farm workers. Am J Industrial Medicine 1997:32:301-302.

Keifer MC, editor. Human Health Effects of Pesticides. Occupational Medicine State of the Art Reviews, 12 (2) 1997

Yuknavage K, Fenske RA, Kalman D, Keifer MC, Furlong CE. Simulated dermal contamination with capillary samples and field cholinesterase biomonitoring. J Tox Environ Health 51:315-55 1997

Keifer MC, Mihuran RK. Chronic Neurological Effects of Pesticide Overexposure. Occupational Medicine State of the Art Reviews, 12(2)291-304, 1997

Keifer MC, Arne KH. Toxicity Testing of Pesticides Sold in the United States. Occupational Medicine State of the Art Reviews, 12(2):365-370, (1997).

Back to top

© 2009, Pacific Northwest Agricultural Safety and Health Center (PNASH) Center
(206) 616-1958, (800) 330-0827, pnash@u.washington.edu

Department of Environmental and Occupational Health Sciences
School of Public Health, University of Washington
Box 357234, Seattle, WA 98195-7234


Home | Overview | Research | Education | Publications | Opportunities | Links