jacob hildebrandt, phd

Jacob Hildebrandt, PhD

Professor, Physiology, and Biophysics
Division of Pulmonary and Critical Care Medicine

Contact Information

University of Washington Medical Center
1959 N.E. Pacific, Campus Box 356522
Seattle, WA 98195-6522

Academic Office: (206) 543-3166
Fax: (206) 685-8673


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Education and Training

B.A. in Physics and Chemistry, University of British Columbia, Vancouver, B.C, Canada, 1957.

M.Sc. in Biophysics, University of British Columbia, Vancouver, B.C, Canada, 1960.

Ph.D. in Physiology and Biophysics, University of Washington, Seattle, WA, 1966.

Research Interests

Using the tools of physiological research, physics, and mathematics to investigate pulmonary vascular mechanics, microvascular heterogeneity, effects of liquid ventilation, heterogeneity of ventilation, bronchial circulation, respiratory mechanics, diffusion limitation and modeling in physiology.

Representative Publications

VanLobensels EM, Anderson JC, Hildebrandt J, Hlastala MP. Modeling diffusion limitation of gas exchange in lungs containing perfluorocarbon. J Appl Physiol 86:273-284, 1999.

Mates EA, Hildebrandt J, Jackson JC, Tarczy-Hornoch P, Hlastala MP: Shunt and ventilation perfusion distribution during partial liquid ventilation in healthy piglets. J App Physiol 82: 933-942, 1997.

Li MH, Hildebrandt J, Hlastala MP: Quantitative analysis of transpleural flux in the isolated lung. J App Physiol 82:545-551, 1997.

Carvalho P, Hildebrandt J, Charan NB: Effects of progressive tension pneumothorax on pulmonary and bronchial arterial blood flow. J App Physiol 81:1664-1669, 1996.

Mutoh T, Lamm WJE, Embree LJ, Hildebrandt J, Albert RK: Volume infusion produces abdominal distension, lung compression, and chest wall stiffening in pigs. J App Physiol 72:575-582, 1992.


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