Timothy R. Watkins, M.D., MSc


Clinical Assistant Professor
Division of Pulmonary and Critical Care Medicine
Assistant Member, Research Division
Puget Sound Blood Center

Contact Information

Harborview Medical Center
Campus Box 359762
325 - 9th Avenue
Seattle, WA 98104
Academic Office: (206) 744-3356
Fax: (206) 744-8584
Research Page

Puget Sound Blood Center, Research Institute
921 Terry Avenue, Seattle, WA 98104
Office: (206) 568-2246  /  Fax: (206) 587-6056

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Education and Training

B.S. in Biology, Ohio University, Athens Ohio 1996.

M.D., Ohio State University College of Medicine and Public Health, Columbus, Ohio. 2000.

Residency, Internal Medicine, University of Wisconsin, Madison Wisconsin, 2003.

Chief Resident, Internal Medicine, University of Wisconsin, Madison, Winconsin, 2004.

Fellowship, Pulmonary and Critical Care Medicine, University of Washington, Seattle, WA, 2007.

MSc in Public Health - Epidemiology, University of Washington, Seattle, WA, 2011.

ACLS certified

Research Interests

Dr. Watkins performs clinically-oriented translational research, studying outcomes following critical illness and injury, examining specifically how blood product transfusions might contribute to adverse clinical outcomes. His research areas of interest include examining the clinical and biologic relationships between blood product transfusions and the development of lung injury, sepsis, and multiple organ failure. He is focusing on elements of blood product processing, storage, and even blood donor health-related factors in order to identify mechanisms to improve transfusion safety in critically ill and injured populations. These groups seem especially vulnerable to transfusion-associated complications.

Dr. Watkins currently holds a career development award from the National Institutes of Health, National Institute of General Medical Sciences, investigating the effect of blood product storage time on the development of trauma-associated lung injury. Through this project he is also working to determine whether cell-derived microparticles are a meaningful component of the RBC storage lesion, and is investigating their potential role as important biomarkers of adverse outcomes in transfused trauma patients.

Representative Publications

Watkins TR, Rubenfeld GD, Martin TR, Nester TA, Caldwell E, Billgren J, Ruzinski J, Nathens AB. Effects of leukoreduced blood on acute lung injury after trauma: a randomized controlled trial. Crit Care Med 2008;36:1493-9.

Seymour CW, Kahn JM, Cooke CR, Watkins TR, Heckbert SR, Rea TD. Prediction of critical illness during out-of-hospital emergency care. JAMA 2010;304(7):747-54.

Stapleton RD, Martin TR, Weiss NS, Crowley JJ, Gundel SJ, Nathens AB, Ruzinski JY, Caldwell E, Curtis JR, Heyland DK, Watkins TR, Parsons PE, Martin JM, Wurfel MM, Hallstrand TS, Sims KA, Neff MJ . A phase II randomized placebo-controlled trial of omega-3 fatty acids for the treatment of acute lung injury. Crit Care Med 2011;39(7):1655-62.

Parsons EC, Hough CL, Seymour CW, Cooke CR, Rubenfeld GD, Watkins TR for the NHLBI ARDS Clinical Network. Red blood cell transfusion and outcomes in patients with acute lung injury, sepsis, and shock. Critical care 2011;15(5):R221.

Watkins TR, Nathens AB, Cooke CR, Psaty BM, Maier RV, Cuschieri J, Rubenfeld, GD. Acute Respiratory Distress Syndrome after Trauma: Development and Validation of a Predictive Model. Crit Care Med 2012;40(8):2295-2303.


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