EDUCATION AND TRAINING
B.S. in Zoology, Washington State University,
Pullman, 1960.
M.D., University of Washington, Seattle, 1964.
Internship in Internal Medicine, Bellevue
Hospital Center, Second Cornell Medical Division,
New York, NY, 1965.
Residency in Internal Medicine, The New York
Hospital, Cornell Medical Center, New York, NY
1966-67.
Fellowship in Pulmonary Diseases (American
Thoracic Society Fellowship), University of
Colorado Medical Center, Denver, 1971.
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CURRENT RESEARCH INTERESTS
To improve our understanding of the epidemiology
of acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS).
To investigate the evolution of the inflammatory
process in the blood and the lung to better
understand the pathogenesis of lung injury. To
investigate new treatment options for patients
with, or at risk for ALI and/or ARDS.
These investigations will allow early
identification of patients at particularly high
risk for development of ALI/ARDS, as well
as identifying the inflammatory mechanisms
involved in their time course interactions and
correlation with clinical characteristics or
events. These data are necessary for the
appropriate design of clinical intervention
trials. The ultimate goal of providing this
information would be to enhance our ability to
identify specific interventions which are likely
to beneficially affect patients at high risk for
ARDS and MODS.
REPRESENTATIVE
PUBLICATIONS
Matute-Bello G, Liles WC, Radella II F, Steinberg KP, Ruzinski JT, Hudson LD, Martin TR. Modulation of neutrophil apoptosis by granulocyte colony-stimulating factor and granulocyte/macrophage colony-stimulating factor during the course of acute respiratory distress syndrome. Crit Care Med 2000; 28:1-7
The ARDS Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342: 1301-1308
Park WY, Goodman RB, Steinberg KP, Ruzinski JT, Radella F II, Park DR, Pugin J, Skerrett SJ, Hudson LD, Martin TR. Cytokine balance in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 2001; 164:1896-1903
Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD. Incidence and outcomes of acute lung injury: Results from the King County Lung Injury Project. N Engl J Med 2005;353:1685-1693
The NIH NHLBI ARDS Network (Hudson LD, writing committee member and study co-chair). Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med 2006; 354:1671-1684
Treggiari MM, Martin DP, Yanez ND, Caldwell E, Hudson LD, Rubenfeld GD. Effect of intensive care unit organizational model and structure on outcomes in patients with acute lung injury. Am J Respir Crit Care Med; 2007; 176:685-690
Schnapp LM, Vaught M, Park DR, Rubenfeld G, Goodman RB, Hudson LD. Implementation and impact of a translational research training program in pulmonary and critical care medicine. Chest 2008 Nov 18 [Epub ahead of print] PMID: 19017887
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