EDUCATION
AND TRAINING
A.B. in Biochemical Sciences, Princeton
University, Princeton, NJ, 1974.
M.D., University of California, San Diego, La
Jolla, CA, 1979.
Residency in Internal Medicine, Hospital of the
University of Pennsylvania,
Philadelphia, PA, 1983.
Fellowship in Pharmacology, University of
Florida, Gainesville, FL, 1980.
Fellowship in Pulmonary and Critical Care
Medicine, University of Washington, Seattle, WA,
1985.
Fellowship in Respiratory Medicine, Hammersmith
Hospital, Royal Postgraduate Medical School,
University of London, England, 1987.
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CURRENT RESEARCH
INTERESTS
Cytoprotective effect of erythropoietin and other NO mediators in acute lung injuries
Influence of carbonic anhydrase, carbon dioxide, nitric oxide and red cell hemoglobin on V/Q matching, gas exchange,
alveolar fluid reabsorption, and hypoxic vascular regulation in normal and diseased lungs
Adaptation and maladaptation in animals and humans to high altitude hypoxia: renal and pulmonary responses
with emphasis on acute mountain sickness and high altitude pulmonary edema
Comparative aspects of gas exchange, acid-base, cardiovascular and renal physiology in fish
and other non-mammalian vertebrates
Bronchoscopic lung volume reduction by brief regionally targeted applications of heated water vapor.
REPRESENTATIVE PUBLICATIONS
Swenson ER, Gibbs JS, Maggiorini M, Mongovin S, Mairbaurl H, Bartsch P. Pathogenesis of high altitude pulmonary edema:
Inflammation is not a pathogenetic factor. J Am Med Assoc. 287:2228-2235, 2002.
Brogan TV, Robertson HT, Lamm W, Souders J, Swenson ER. Carbon dioxide added late in inspiration reduces V/Q heterogeneity without causing respiratory acidosis.
J Appl Physiol. 96:1894-1898, 2004.
Swenson KE, Eveland R, Gladwin MT, Swenson ER. Nitric oxide (NO) in normal and hypoxic vascular regulation of the spiny dogfish, Squalus acanthias.
J Exp Zool 303:154-60, 2005.
Kregenow DA, Rubenfeld G, Hudson LD, Swenson ER. Hypercapnic acidosis and mortality in acute lung injury. Crit Care Med 34:1-7, 2006.
Deem S, Min J, Eveland R, Moulding J, Swenson ER. Red blood cells prevent inhibition of hypoxic pulmonary vasoconstriction by nitrite in isolated, perfused rat lungs.
Am J Physiol 292:H963-70, 2007.
Shimoda L, Sylvester JT, Swenson ER. Inhibition of hypoxia-induced Ca++ responses in PA smooth muscle cells by acetazolamide is independent of carbonic anhydrase inhibition.
Am J Physiol 292:L1002-12, 2007.
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