research

Biomedical Research

The research environment at the University of Washington is incredibly rich, energetic and supportive. The research activities within the Division of Pulmonary and Critical Care Medicine are consequently diverse and continually evolving to remain on the leading edge of science. To compliment this diversity, we have considerable depth in six key areas of research. While these core programs are described below as self-supporting groups, one of the great strengths of our divisional research is that all of the research programs draw knowledge, tools and support from the other groups.  These interactions create a very robust research environment that is supportive of fellows and junior faculty and is exceptionally productive.

We have tremendous strength in our Lung Immunity and Repair Program that is based at the Center for Lung Biology at the University of Washington. The mission of the Center for Lung Biology is to provide a nexus for performing, coordinating, enhancing, and stimulating basic research directed toward understanding fundamental mechanisms of lung development, repair, and disease. We have several other prominent research laboratories that also focus on molecular and cell biology. These laboratories concentrate on areas such as acute lung injury and defense mechanisms against pulmonary infections. We also have a long history and tremendous expertise in physiologic research concentrating on pulmonary vasculature and the coordination of ventilation and perfusion in the lung. These research programs are concentrated within the Integrative Respiratory Physiology Program that integrates molecular, cellular, and genetic biology into whole lung physiology. We have a strong research program performing epidemiology and outcomes research that has focused on the Clinical Investigation of Acute Lung Injury and Acute Respiratory Distress Syndrome in the past and is expanding into a number of other areas, including outcomes of critical care, end-of-life care, chronic obstructive lung disease, asthma, cystic fibrosis, lung transplantation, cost-effectiveness research in both academic and community hospitals and sleep disordered breathing. Our Division faculty were one of the first to recognize the importance of translation research in pulmonary and critical care. We have pioneered much of the development in this field and have established a formal Translational Research Program to support the career development of fellows and faculty interested in science that incorporates both bench and clinical research. One of our strongest programs that has developed directly from our Translational program is our Genetic Epidemiology of Critical Care. The research is strongly supported by the wealth of research being performed at the University of Washington in genetics and clinical database development. The Seattle community and the University of Washington are world leaders in global health and our Division is beginning to build its own Global Health Program to address the research and clinical needs for pulmonary and critical care in under-resourced regions.

The University of Washington is one of the most highly funded academic institutions in the country and our Division contributes significantly in this arena. Over the last five years, our faculty has contributed an annual average of 25 book chapters and 119 articles to a wide variety of scientific journals, as well as 55 abstracts each year to national and international scientific meetings. Our faculty also contribute by acting as members of study sections for the National Institutes of Health and other research funding agencies. Finally, our faculty provide national leadership in such organizations as the American Thoracic Society, the American College of Chest Physicians and the American Academy of Sleep Medicine.

 

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