research

H. Thomas Robertson

Professor, Medicine and Physiology and Biophysics

MD

Faculty Web Page

Last Updated:  September 7, 2010


Research Focus

My career research focus has been the study of pulmonary gas exchange, with my most recent work utilizing both imaging techniques and microsphere deposition techniques to study the spatial distribution of regional ventilation and perfusion in a number of animal models. A second research interest has been study of the cardiovascular and pulmonary responses to exercise in both normal subjects and patients with pulmonary, cardiac and renal disorders.

 

Relevant Publications

Robertson HT, Haley NR, Guthrie M, Cardenas D, Eschbach JW, Adamson JW: Recombinant erythropoietin improves exercise capacity in anemic hemodialysis patients. Am J Kid Dis 15:325-332, 1990.

Glenny RW, Robertson HT: Fractal properties of pulmonary blood flow: Characterization of spatial heterogeneity. J Appl Physiol 69:532-545, 1990

Hopkins SR, McKenzie DC, Schoene RB, Glenny RW, Robertson HT. Pulmonary gas exchange during exercise in athletes: I. Ventilation-perfusion mismatch and diffusion limitation. J Appl Physiol 77:912-917, 1994.

Robertson HT, Glenny RW, Stanford D, McInnes LM, Luchtel DL, Covert D. High-resolution maps of regional ventilation utilizing inhaled fluorescent microspheres. J. Appl. Physiol.82:943-953, 1997.

Glenny RW, Bernard S, Robertson HT. Pulmonary blood flow remains fractal down to the level of gas exchange. J Appl Physiol 89:742-748, 2000.

Glenny RW, Lamm WE, Bernard S, An D, Chornuk M, Pool SL, Wagner WW, Hlastala MP, Robertson HT. Selected contribution: redistribution of pulmonary perfusion during weightlessness and increased gravity. J Appl Physiol 89:1239-1248, 2000

Robertson HT, Pellegrino R, Pini D, Oreglia J, DeVita S, Brusasco V, Agostoni P. Exercise response following rapid intravenous infusion of saline in healthy humans. J Appl Physiol.97:697-703, 2004.

Robertson HT, Kreck TC, Krueger MA. The spatial and temporal heterogeneity of regional ventilation: Comparison of measurements by two high-resolution methods. Resp Physiol Neurobiol 148:85-95, 2005.

Robertson HT, Neradilek B, Polissar NL, Glenny RW. Sporadic coordinated shifts of regional ventilation and perfusion in juvenile pigs with normal gas exchange. J Physiol, 583:743-752, 2007.

Robertson HT, Krueger MA, Lamm WJ, Glenny RW. High-Resolution Spatial Measurements of Ventilation-Perfusion Heterogeneity in Rats. J Appl Physiol 108: 1395-1401, 2010

 

Active Funding

Funding source

Project Title

Investigator Role

Funding dates

NIH

3D Imaging & Modeling

Co-Investigator

08/2010-07/2015


Current Mentees

Name

Degree

Project

None




Past Mentees

Name

Degree

Current title

Location

Robb Glenny

 MD

Professor

University of Washington, Seattle WA

Erik Swenson

MD

Professor

University of Washington, Seattle WA


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