Office of Research
NHGRI Genome Sequencing Program Analysis Centers (U01)
NHGRI seeks to establish NHGRI Genome Sequencing Program Analysis Centers (GSPAC), which will undertake computational analyses of the data produced by the NHGRI Genome Sequencing Program (GSP; See "Companion Funding Opportunities") with the purpose of extracting genomic and biological knowledge.
Specifically, the GSPACs will have two roles. First, they will undertake novel, investigator-initiated analyses that will cut across the individual projects and grants that are the primary data producing constituents of the overall GSP. These analyses may also use data generated by other large-scale genomics projects. GSPACs will develop improved or novel analyses and methods for all non-automated aspects of characterizing sequence variants in the data, after lower level data processing and variant calling. NHGRI has particular interest in questions about identifying associations between variants and disease phenotypes; analyses using existing functional data to leverage associations and/or make functional inferences; means to improve study design; and other higher level analyses.
Second, the GSPACs will work together with the other GSP components on cross-program analyses that are directly relevant to goals defined in the Companion Funding Opportunities, which currently include defining the point at which a common disease/rare variant genome sequencing study is “comprehensive” or complete, and developing specifications for sample sets that could serve as common controls for common disease genome sequencing studies.
Application Instructions
Please submit:
- a one-page letter of intent with a description of proposed aims and approach
- Biosketch or CV of the PI
- A letter of support from the Dean or Chair. This letter of support signifies that the Dean or Chair have ensured that the nominee and application are likely to be of sufficient quality to be competitive nationally
to research@uw.edu by 5:00 PM Thursday, July 2, 2015. Full proposals are due to the sponsor 8/25/15, so you will need to have your materials in to the Office of Sponsored Programs by 8/17/15 for processing, if given the go ahead by the Proposal Review Committee.
Inquiries and Contact Information
Investigators who identify a grant, award or fellowship program that restricts the number of applications that can be submitted from an Institution should immediately contact their Chairperson, Associate Dean for Research (or Dean, if no ADR) and the Office of Research (see below) if they intend to prepare a response. Failure to do so, or to meet the deadlines for submission of pre-proposal, will preclude submission of the application through the Office of Sponsored Programs.
For general inquiries, or to request a listing of a limited submission opportunity that should be but is not already listed, please email us at limitedsubs@uw.edu.