Office of Research

Network for Emergency Care Clinical Trials: Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) - Network Clinical Center (Hub) (U24)

Limited Submissions

The purpose of this funding opportunity announcement (FOA) is to invite applications for Clinical Centers (Hubs) in Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN).  SIREN will enable conduct of high-quality, multi-site clinical trials to improve the outcomes for patients with neurologic, cardiac, respiratory, and hematologic, and trauma emergency events. SIREN will consist of one Clinical Coordinating Center (CCC), one Data Coordinating Center (DCC) and up to 10 clinical centers (Hubs). A Hub will typically be an academic center or tertiary referral center which will actively enroll patients into every clinical trial performed in SIREN, regardless of disease focus.  A Hub will additionally provide scientific leadership and administrative oversight to its multiple satellite sites ("Spokes").  Together the Hub and Spokes will provide access to a large and varying patient population for clinical trials. SIREN will implement a total of at least four large (>1,000 patient) simple, pragmatic clinical trials in the emergency department and pre-hospital settings. The clinical trials will be meritorious, peer–reviewed projects which will be awarded under separate funding announcements.

 

This FOA solicits applications for the SIREN Hubs. Since the Spokes are identified, recruited and overseen by the applicant Hubs, there is no separate FOA for Spokes. Separate FOAs are issued to solicit applications for the Clinical Coordinating Center (RFA-NS-16-014) and Data Coordinating Center (RFA-NS-16-015).  

Application Instructions

Please submit:

  1. a one-page letter of intent with a description of proposed aims and approach
  2. Biosketch or CV of the PI
  3. A letter of support from the Dean or Chair. This letter of support signifies that the Dean or Chair have ensured that the nominee and application are likely to be of sufficient quality to be competitive nationally

 

to research@uw.edu by 5:00 PM Thursday, April 7, 2016. Full proposals are due to the sponsor 6/1/16, so you will need to have your materials in to the Office of Sponsored Programs by 5/24/16 for processing, if given the go ahead by the Proposal Review Committee.

Opportunity Details

Program web page

Program Announcement No.

RFA-NS-16-016

Deadlines
04/07/2016 UW Internal Deadline Closed
05/24/2016 OSP Deadline
06/01/2016 Sponsor Deadline
Sponsor

National Institutes of Health (NIH)

Funding amount

$552,000

Maximum Number of Applications

1

Eligible groups
  • All campus

Inquiries and Contact Information

Investigators who identify a grant, award or fellowship program that restricts the number of applications that can be submitted from an Institution should immediately contact their Chairperson, Associate Dean for Research (or Dean, if no ADR) and the Office of Research (see below) if they intend to prepare a response. Failure to do so, or to meet the deadlines for submission of pre-proposal, will preclude submission of the application through the Office of Sponsored Programs.

For general inquiries, or to request a listing of a limited submission opportunity that should be but is not already listed, please email us at limitedsubs@uw.edu.