Network for Emergency Care Clinical Trials: Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) - Data Coordinating Center (DCC) (U24)

The purpose of this funding opportunity announcement (FOA) is to invite applications for the Data Coordinating Center (DCC) for Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN).  SIREN will enable conduct of high-quality, multi-site clinical trials to improve the outcomes for patients with neurologic, cardiac, respiratory, hematologic, and trauma emergency events. SIREN will consist of one Clinical Coordinating Center (CCC), one Data Coordinating Center (DCC) and up to 10 clinical centers (Hubs).   The DCC will have responsibility for data management, data quality, statistical analysis, Data Safety Monitoring Board(s) (DSMB) and reporting to regulatory and oversight groups. SIREN will implement a total of at least four large (>1,000 patient) simple, pragmatic clinical trials in the emergency department and pre-hospital settings.  The clinical trials will be meritorious, peer–reviewed projects which will be awarded under separate funding announcements. 

This FOA solicits applications for the SIREN Data Coordinating Center. Separate FOAs are issued to solicit applications for the Clinical Coordinating Center (RFA-NS-16-014) and Clinical Hubs (RFA-NS-16-016).  

Application Instructions

Please submit:

1. a one-page letter of intent with a description of proposed aims and approach
2. Biosketch or CV of the PI
3. A letter of support from the Dean or Chair. This letter of support signifies that the Dean or Chair have ensured that the nominee and application are likely to be of sufficient quality to be competitive nationally

to research@uw.edu by 5:00 PM Thursday, April 7, 2016. Full proposals are due to the sponsor 6/1/16, so you will need to have your materials in to the Office of Sponsored Programs by 5/24/16 for processing, if given the go ahead by the Proposal Review Committee.