Office of Research

Tissue Chip Testing Centers: Validating Microphysiological Systems (U24)

Limited Submissions

This Funding Opportunity Announcement (FOA) invites applications for Tissue Chip Testing Center(s) (TCTC) that will provide resources and infrastructure for the validation of tissue chips being developed as part of the NIH Tissue Chip (TC) Program or NIH Microphysiological Systems (MPS) Program. The MPS program supports a consortium of investigators developing accurate cellular and organ microsystems representative of human physiology for the evaluation of drug efficacy and toxicity (RFA-RM-11-022).  The developed in vitro MPS platforms are representative of major organs and tissues in the human body and need to be validated for their predictive capabilities in the assessment of biomarkers, and the bioavailability, efficacy, and toxicity of therapeutic agents prior to entry into clinical trials.  Validation of the tissue chips will be conducted through the TCTC that will be responsible for the testing of a select group of compounds using predefined assays and biomarkers according to pharmaceutical industry standards, and for the integration of the data into a public database.

Application Instructions

Please submit:

  1. a one-page letter of intent with a description of proposed aims and approach
  2. Biosketch or CV of the PI
  3. A letter of support from the Dean or Chair. This letter of support signifies that the Dean or Chair have ensured that the nominee and application are likely to be of sufficient quality to be competitive nationally

 

to research@uw.edu by 5:00 PM Thursday, April 21, 2016. Full proposals are due to the sponsor 5/17/16, so you will need to have your materials in to the Office of Sponsored Programs by 5/9/16 for processing, if given the go ahead by the Proposal Review Committee.

Opportunity Details

Program web page

Program Announcement No.

RFA-TR-16-006

Deadlines
04/21/2016 UW Internal Deadline Closed
05/09/2016 OSP Deadline
05/17/2016 Sponsor Deadline
Sponsor

National Institutes of Health (NIH)

Funding amount

$2,000,000

Maximum Number of Applications

1

Eligible groups
  • All campus

Inquiries and Contact Information

Investigators who identify a grant, award or fellowship program that restricts the number of applications that can be submitted from an Institution should immediately contact their Chairperson, Associate Dean for Research (or Dean, if no ADR) and the Office of Research (see below) if they intend to prepare a response. Failure to do so, or to meet the deadlines for submission of pre-proposal, will preclude submission of the application through the Office of Sponsored Programs.

For general inquiries, or to request a listing of a limited submission opportunity that should be but is not already listed, please email us at limitedsubs@uw.edu.