Office of Research

The Experimental Therapeutics Clinical Trials Network (ETCTN) Pharmacokinetic Resource Laboratories (U24 Clinical Trial Not Allowed)

Limited Submissions

The purpose of this Funding Opportunity Announcement (FOA) issued by The National Cancer Institute (NCI) is to create Pharmacokinetics Resource Laboratories (PK Laboratories) that will support the Experimental Therapeutics Clinical Trials Network (ETCTN). The PK Laboratories will be expected to organize specimen collection and subsequent analysis of pharmacokinetic endpoints, drug-drug interactions, cytochromes P450 (CYP) interactions, and food effects in ETCTN studies of NCI Investigational New Drug (IND) agents. The overarching goal of the ETCTN PK Laboratories is to advance the clinical development of NCI-IND agents through achieving comprehensive understanding of pharmacokinetic behavior of these agents studied in ETCTN protocols. The ETCTN Pharmacokinetic Resource Laboratories will assure the availability of physicians, clinical pharmacologists, nurses and scientists who have the appropriate expertise in pharmacokinetic studies for early drug development and translational research. This FOA seeks U24 cooperative agreement applications from multidisciplinary groups that will conduct all pharmacokinetic studies for ETCTN early phase clinical trials filed to the IND applications in NCI’s Division of Cancer Treatment and Diagnosis (DCTD), Cancer Therapy Evaluation Program (CTEP). 

Application Instructions

Please submit:

  1. a one-page letter of intent with a description of proposed aims and approach
  2. CV (not NIH format)  of the PI
  3. A letter of support from the Dean or Chair. This letter of support signifies that the Dean or Chair have ensured that the nominee and application are likely to be of sufficient quality to be competitive nationally

 

to research@uw.edu by 5:00 PM Thursday March 7, 2019. Proposals are due to the sponsor 5/22/19, so you will need to have your materials in to the Office of Sponsored Programs by 5/14/19 for processing, if given the go ahead by the Proposal Review Committee.

Opportunity Details

Program web page

Program Announcement No.

RFA-CA-19-008

Deadlines
03/07/2019 UW Internal Deadline Closed
05/14/2019 OSP Deadline
05/22/2019 Sponsor Deadline
Sponsor

National Institutes of Health (NIH)

Funding amount

$1,920,000

Maximum Number of Applications

1

Eligible groups
  • All campus

Inquiries and Contact Information

Investigators who identify a grant, award or fellowship program that restricts the number of applications that can be submitted from an Institution should immediately contact their Chairperson, Associate Dean for Research (or Dean, if no ADR) and the Office of Research (see below) if they intend to prepare a response. Failure to do so, or to meet the deadlines for submission of pre-proposal, will preclude submission of the application through the Office of Sponsored Programs.

For general inquiries, or to request a listing of a limited submission opportunity that should be but is not already listed, please email us at limitedsubs@uw.edu.