2019 Translational Research Grant

The foundation encourages research on the biological basis of cancer disparities experienced by patients from minority ethnic or racial populations in areas related to causes, aggressiveness, treatment or relapse. Cancers in which ethnic and racial disparities have previously been demonstrated include: lung and bronchus, colon and rectum, breast, prostate, uterine, cervix, stomach and liver.

The V Foundation for Cancer Research seeks to support translational research projects within the scope of all types of cancers.

• Definition of a translational research project: Translational projects should move a novel strategy from the laboratory into a human clinical trial or use specimens from a clinical trial to develop biomarkers or mechanisms. The research should apply in some direct way to human beings within the time frame of less than 3 years. If biomarker research is undertaken, a validation set or independent clinical trial is essential. A plan for biomarker validation, if applicable, must be included in any proposal. The endpoint of the project should be the planning or initiation of a new clinical trial.

Eligibility Requirements

Eligibility: 

The nominated applicant must be the lead Principal Investigator (PI) on the Translational Award research team. The applicant must meet all of the following criteria to be eligible to submit an application:

• The nominee must be nominated by their Cancer Center Director if the research institution is a cancer center. If the research institution is not a cancer center, then the provost, dean or other senior research administrative official who is responsible for the internal nominee selection process may make the nomination. We do not review unsolicited applications.
• Applicant must be employed at a non-profit research institution (e.g. 501c3, Section 170).
• By the Due Date of the Application, the applicant who will lead the research team must have all the following:
• Be a scientist in a tenure-track faculty position at their cancer research institution. Non-promotable, adjunct, affiliated, temporary, part-time or acting faculty positions are not eligible for Principal Investigator nomination to lead the Translational Research Team.
• Applicants must be either a US or Canadian Citizen, or have a legal permit to work in the USA (either temporary or permanent).

Funding:

• $600,000 total paid in three annual installments of $200,000/year.
• A maximum of 10% of the grant may be used annually to offset the indirect costs of the project.
• This award is not listed on Exhibit A. The endorsed applicant must have Fred Hutch Director’s Office approval for unrecovered F&A costs before submitting an application, and should work with their Division Administrator to complete this task.

Application Instructions

Please submit:

1. a one-page letter of intent with a description of proposed aims and approach
2. Biosketch (not NIH format) or CV of the PI
3. A letter of support from the Dean or Chair. This letter of support signifies that the Dean or Chair have ensured that the nominee and application are likely to be of sufficient quality to be competitive nationally

to research@uw.edu by 5:00 PM Monday March 29, 2019. The UW limited submissions review committee will review and rank pre-proposals, then send the rankings to the Fred Hutch review committee for final decisions.