Office of Research
Cancer Prevention Clinical Trials Network (CP-CTNet): CP-CTNet Sites (UG1 Clinical Trial Required)
Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) proposes and will support the Cancer Prevention Clinical Trials Network (CP-CTNet), for which the goals are as follows:
- Design and conduct of early phase clinical trials to assess the safety, tolerability, and cancer preventive potential of agents and interventions of varying classes, many of which target molecules or processes known to be important during carcinogenesis. These trials include phase 0 (micro-dosing), phase I (dose-finding), and phase II (preliminary efficacy) clinical trials;
- Characterization of the effects of these agents and interventions on their molecular targets, as well as on other biological events associated with cancer development (such as cell proliferation, apoptosis, growth factor expression, oncogene expression, immune response) and correlation of these effects with clinical endpoints.
- Development of further scientific insights into the mechanisms of cancer prevention by the agents examined, including the development of novel potential markers as determinants of response.
CP-CTNet consists of two types of components:
- CP-CTNet Sites (covered by this FOA and through funding of previous RFA-CA-18-029); and
- One CP-CTNet Data Management, Auditing, and Coordinating Center (funded previously).
The CP-CTNet Sites will provide scientific leadership in development and conduct of early phase cancer prevention clinical trials as well as in the management and analysis of the data.
Application Instructions
Please submit:
- a one-page letter of intent with a description of proposed aims and approach
- CV (not NIH format) of the PI
- A letter of support from the Dean or Chair. This letter of support signifies that the Dean or Chair have ensured that the nominee and application are likely to be of sufficient quality to be competitive nationally
to research@uw.edu by 5:00 PM Thursday August 1 2019. Proposals are due to the 8/29/19 so you will need to have your materials in to the Office of Sponsored Programs by 8/20/19 for processing, if given the go ahead by the Proposal Review Committee.
Inquiries and Contact Information
Investigators who identify a grant, award or fellowship program that restricts the number of applications that can be submitted from an Institution should immediately contact their Chairperson, Associate Dean for Research (or Dean, if no ADR) and the Office of Research (see below) if they intend to prepare a response. Failure to do so, or to meet the deadlines for submission of pre-proposal, will preclude submission of the application through the Office of Sponsored Programs.
For general inquiries, or to request a listing of a limited submission opportunity that should be but is not already listed, please email us at limitedsubs@uw.edu.