Office of Research

Breakthrough Science Initiative Awards Program

Ono Pharma Foundation announces the start of the ninth year of the annual Breakthrough Science Initiative Awards Program (Ono Initiative) in the United States and Canada. Proposals from Principal Investigators will be considered for high-risk and high-reward science research projects which have the potential to lead to science discoveries/solutions and, based on further research, to breakthrough treatments for patients.

Target research of Chemical Biology is not specified by the Ono Initiative. For 2025, subjects of interest include but are not limited to:

  • Modulating interactome and cell/tissue crosstalk
  • Manipulating biomolecular condensates and protein quality control systems
  • Deep understanding and emerging applications of chemical glycobiology
  • New concepts of drug delivery and localization to tissue/cell/organelle
  • Understanding and leveraging allostery in biology

The foundation welcomes projects outside of these subjects.

Application Instructions

Please submit as one combined pdf labeled with PI’s Lastname, Firstname:

  1. A one‐page letter of intent with a description of proposed aims and approach.
  2. If the final application requires a diversity statement or statement of broader impacts, please summarize your plans to address the specific requirements on an additional page.
  3. CV (not biosketch) of the PI including past grant funding.

to limitedsubs@uw.edu by 5:00 PM Wednesday, December 18, 2024. If given the go‐ahead by the Limited Submissions review committee, a required LOI is due to the sponsor 2/14/2025. If invited to send a full proposal, the deadline is 5/8/2025 with the OSP deadline of 4/28/2025.

Opportunity Details

Program web page

Program Announcement No.

2025

Deadlines
12/18/2024 UW Internal Deadline Closed
02/14/2025 Sponsor Deadline
Sponsor

Ono Pharma Foundation

Funding amount

$900,000 (over 3 years)

Maximum Number of Applications

2

Eligible groups
  • All campus

Inquiries and Contact Information

Investigators who identify a grant, award or fellowship program that restricts the number of applications that can be submitted from an Institution should immediately contact their Chairperson, Associate Dean for Research (or Dean, if no ADR) and the Office of Research (see below) if they intend to prepare a response. Failure to do so, or to meet the deadlines for submission of pre-proposal, will preclude submission of the application through the Office of Sponsored Programs.

For general inquiries, or to request a listing of a limited submission opportunity that should be but is not already listed, please email us at limitedsubs@uw.edu.