2000 Publications

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• Papers
• Books and book chapters
• Abstracts

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Papers

• Batal R, Tremblay M, Barrett PHR, Jacques H, Fredenrich A, Mamer O, Davignon J, Cohn JS. Plasma kinetics of apoCIII and apoE in normolipidemic and hypertriglyceridemic subjects. J Lipid Res. 2000; 41: 706-718. [C]
• Bell, B. M. The marginal likelihood for parameters in a discrete Gauss-Markov process. IEEE Transactions on Signal Processing 48:870-873, 2000. [T]
• Caumo A, Bergman RN, Cobelli C. Insulin sensitivity from meal tolerance tests in normal subjects: a minimal model index. J Clin Endocrinol Metab. 2000 Nov;85(11):4396-402.
• Davis TME, Daly F, Walsh J, Ilett K, Beilby J, Dusci L, Barrett PHR. Pharmacokinetics and pharmacodynamics of gliclazide in Caucasian and Australian Aboriginal patients with type 2 diabetes. J Clin Pharmacol 2000; 49: 223-230. [C]
• Davis TME, Binh TQ, Thu LTA, Rossi R, Danh PT, Barrett PHR, Beilby J. Pharmacokinetics of retinyl palmitate and retinol after intramuscular retinyl palmitate administration in severe falciparum malaria. Clin Sci 2000; 99: 433-441. [C]
• Hoffman, R. P., Vicini P, W. I. Sivitz, and C. Cobelli. Pubertal adolescent male-female differences in insulin sensitivity and glucose effectiveness determined by the one compartment minimal model, Pediatric Research 48: 384-388, 2000. [C]
• Konrad T, Steinmuller T, Vicini P, Toffolo G, Grewerus D, Schuller A, Bechstein WO, Usadel KH, Cobelli C, Mahon A, Wittmann W, Klar E, Golling M, Neuhaus P. Evidence for impaired glucose effectiveness in cirrhotic patients after liver transplantation. Metabolism 49: 367-72, 2000. [C]
• Konrad T, Steinmuller T, Vicini P, Toffolo G, Grewerus D, Schuller A, Bechstein WO, Usadel KH, Cobelli C, Neuhaus P. Regulation of glucose tolerance in patients after liver transplantation: impact of cyclosporin versus tacrolimus therapy. Transplantation 27; 69: 2072-8, 2000. [C]
• Konrad T, Zeuzem S, Toffolo G, Vicini P, Teuber G, Briem D, Lormann J, Lenz T, Herrmann G, Berger A, Cobelli C, Usadel K. Severity of HCV-induced liver damage alters glucose homeostasis in noncirrhotic patients with chronic HCV infection, Digestion 62: 52-59, 2000. [C]
• Konrad, T., S. Zeuzem, Vicini P, G. Toffolo, D. Briem, J. Lormann, G. Herrmann, A. Berger, K. Kusterer, G. Teuber, C. Cobelli and K.H. Usadel. Evaluation of factors controlling glucose tolerance in patients with HCV infection before and after 4 months therapy with interferon-alpha. European Journal of Clinical Investigation 30: 111-121, 2000. [C]
• Magni, P, Bellazzi, R, Sparacino, G and C.Cobelli. Bayesian identification of a population compartmental model of C-peptide kinetics. Annals of Biomedical Engineering, vol: 28,pp. 812-823, 2000. [C]
• Nielsen MF, Nyholm B, Caumo A, Chandramouli V, Schumann WC, Cobelli C, Landau BR, Rizza RA, Schmitz O. Prandial glucose effectiveness and fasting gluconeogenesis in insulin-resistant first-degree relatives of patients with type 2 diabetes. Diabetes. 2000 Dec;49(12):2135-41.
• Nucci G, Cobelli C. Models of subcutaneous insulin kinetics. A critical review. Comput Methods Programs Biomed. 2000 Jul;62(3):249-57. Review. [C]
• Parhofer KG, Barrett PHR, Demant T, Schwandt P. Acute effects of LDL-Apheresis on metabolic parameters of apolipoprotein B. J Lipid Res 2000; 41: 1596-1603. [C]
• Parhofer KG, Barrett PHR, Schwandt P. Atorvastatin improves postprandial lipoprotein metabolism in normolipidemic subjects. J Clin Endo Metab. 2000; 85: 4224-4230. [C]
• Sparacino G, Bardi F, Cobelli C. Approximate entropy studies of hormone pulsatility from plasma concentration time series: influence of the kinetics assessed by simulation. Ann Biomed Eng. 2000 Jun;28(6):665-76. [T]
• Sparacino G, Tombolato C, Cobelli C. Maximum-likelihood versus maximum a posteriori parameter estimation of physiological system models: the C-peptide impulse response case study. IEEE Trans Biomed Eng. 2000 Jun;47(6):801-11. [T]
• Twisk J, Gillian-Daniel DL, Wang L, Tebon A, Barrett PHR, Attie AD. The role of the LDL receptor in apolipoproteinB secretion. J Clin Invest 2000; 105 521-532. [C]
• Ummenhofer WC, Arends RH, Shen DD, Bernards CM. Comparative spinal distribution and clearance kinetics of intrathecally administered morphine, fentanyl, alfentanil, and sufentanil. Anesthesiology. 2000 Mar;92(3):739-53. [C]
• Vicini, P., H.-T. Su and J.J. DiStefano, III. Identifiability and interval identifiability of mammillary and catenary compartmental models with some known rate constants, Mathematical Biosciences 167: 145-161, 2000. [C]
• Vicini, P., and M.J. Kushmerick. Cellular energetics analysis by a mathematical model of energy balance: estimation of parameters in human skeletal muscle. American Journal of Physiology: Cell Physiology 279: C213-C224, 2000. [C]
• Watts GF, Moroz P, Barrett PHR. Kinetics of very low density lipoprotein apolipoprotein B100 in normolipidemic subjects: Pooled analysis of stable isotope studies. Metab 2000; 49: 1204-1210. [C]
• Welty FK, Lichtenstein AH, Barrett PHR, Dolnikowski GG, Schaefer EJ. Effects of apolipoprotein E genotype on apolipoprotein B-48 and apoB-100 kinetics using stable isotopes in humans. Arterioscler Thromb Vasc Biol 2000; 20: 1807-1810. [C]
• Wolfe BM, Barrett PHR, Laurier L, Huff MW. Effects of continuous conjugated estrogen and micronized progesterone therapy upon lipoprotein metabolism in postmenopausal women. J Lipid Res. 2000; 41: 368-375. [C]

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Books and book chapters

• None published this year.

Abstracts

• Barrett, PHR, Chan D, Dane-Stewart C, Stuckey B, Mamo JCL, Redgrave TG, Watts GF. Chylomicron remnant kinetics in postmenopausal women with and without diabetes. Intl. Athero. Soc. Stockholm, Athero 2000. 151:2. [C]
• Barrett, PHR. Pulse-chase studies: Estimating apolipoprotein secretion and post-translational degradation rates. Intl. Athero. Soc. Stockholm, Athero 2000. 151:286. [C]
• Batal R, Tremblay M, Barrett PHR, Jacques H, Davignon J, Cohn J. Overproduction of apoE in patients with type III hyperlipoproteinemia and in patients with other forms of hypertriglyceridemia. Intl. Athero. Soc. Stockholm, Athero 2000. 151: 243 [C]
• Burnett JR, Barrett PHR, Telford DE, Huff MW. The ACAT inhibitor avasimibe increases the fractional clearance rate of postprandial triglyceride-rich lipoproteins. Intl. Athero. Soc. Stockholm, Athero 2000. 151: 134. [C]
• Callegari, T., A. Caumo, C. Cobelli. The Bayesian Two-Compartment Minimal Model of Glucose Kinetics During Standard IVGTT: SAAM II Vs. ADAPT II Implementation. In CD-ROM Proceedings of the World Congress on Medical Physics and Biomedical Engineering, July 23-28, 2000 [C]
• Carr M A, Hokanson JE, Zambon, Deeb SS, Barrett PHR, Purnell JQ, Brunzell JD. Intraabdominal fat accounts for a portion of the gender differences in hepatic lipase activity and LDL/HDL heterogeneity. Circ 2000. [C]
• Chan D, Barrett PHR, Mori TA, Beilin LJ, Redgrave TG, Watts GF. Effect of atorvastatin on apolipoprotein B-100 kinetics in visceral obesity. Intl. Athero. Soc. Stockholm, Athero 2000. 151: [C]
• Chan D, Watts GF, Barrett PHR, James T, Mamo J, Mori TA, Redgrave TG. Effect of atorvastatin on chylimicron remnant metabolism in obese subjects studied with a stable isotope breath test. Intl. Athero. Soc. Stockholm, 2000. 151:137. [C]
• Chan D, Watts GF, Barrett PHR, Mamo J, Mori TA, Martins I, Redgrave TG. Chylomicron remnant metabolism in obese men with and without hypertriglyceridemia. Intl. Athero. Soc. Stockholm, 2000. 151:95. [C]
• Ching H, Pereira E, Stuckey BGA, Barrett PHR, Redgrave TG, Watts GF. Vascular reactivity of the peripheral circulation in pre-menopausal women and post-menopausal women with and without type 2 diabetes. Sydney 2000 [C]
• Ching H, Pereira E, Stuckey BGA, Redgrave TG, Barrett PHR, Watts GF. Vascular reactivity of the peripheral circulation in postmenopausal women with and without type 2 diabetes. Sydney 2000 [C]
• Dane-Stewart C, Watts GF, Mamo JCL, Redgrave TG, Barrett PHR, Dimmitt S. Effect of simvastatin on remnant lipoproteins in heterozygous familial hypercholesterolemia. Intl. Athero. Soc. Stockholm, Athero 2000. 151:38. [C]
• Dodds, M. G., and Vicini P. Assessing convergence in pharmacokinetic Bayesian analysis. Annals of Biomedical Engineering 28: Supplement 1, T-9.24, 2000. [T]
• Foster, D.M. Problems in studying lipoprotein kinetics. Annals of Biomedical Engineering 28: Supplement 1, T-9.12, 2000. [C]
• Lukas, J.C. Pharmacokinetic parameter identifiability and population covariate model determination: to Bayes or not to Bayes? Annals of Biomedical Engineering 28: Supplement 1, T-9.25, 2000. [T]
• Lukas, J.C., and R. Calvo. A diffusion-improved model of ligand-receptor dynamics in vivo: pharmacodynamical simulations of parameter ranges with linear forcing lead to a chaotic attractor. Annals of Biomedical Engineering 28: Supplement 1, T-4-4, 2000. [C]
• Lukas, J.C., M. Watrous and G. L. Drusano. Comparison of NONMEM and NPEM with POP3CM, a new hierarchical parametric empirical Bayes model, using levofloxacin data. Annals of Biomedical Engineering 28: Supplement 1, T-9.27, 2000. [C]
• Magni, P., R. Bellazzi, G. Sparacino, C. Cobelli. Almost-Blind Deconvolution for Input Estimation in Physiological Systems. In CD-ROM Proceedings of the World Congress on Medical Physics and Biomedical Engineering, July 23-28, 2000. [C]
• Parhofer KG, Barrett PHR, Schwandt. Atorvastatin increases the catabolism of chylomicron remnants in normolipidemic subjects. International Atherosclerosis Society, Stockholm, Athero 2000. 151:8. [C]
• Parhofer KG, Barrett PHR, Schwandt. Effect of atorvastatin on postprandial lipoprotein metabolism in normolipidemic subjects. Circ 2000. [C]
• Prigeon RL, S Quddusi, BW Paty, P Vicini, MP Hulquist, DA D’Alessio. Glucagon-like peptide-1 (GLP-1) increases total body glucose effectiveness in humans as measured by the two-compartment minimal model. Journal Of Investigative Medicine 48 (1): 414 Suppl. S Jan 2000 [C]
• Spilker, M. E., A. A. Yao and Vicini P. Tumor diagnosis using population modeling techniques and MRI technology. Annals of Biomedical Engineering 28: Supplement 1, T-9.33, 2000. [C]
• Stuckey BGA, Barrett PHR, Martins IJ, Redgrave TG, Ching H, Pereira E, Dane-Stewart C, Watts GF. Chylomicron remnant kinetics in pre-menopausal women and post-menopausal women with and without type 2 diabetes. Sydney 2000 [C]
• Vicini, P. Disease state and disease progression models. International Journal of Pharmaceutical Medicine 14: 194, 2000. [D]
• Vicini, P. New technologies in pharmacokinetic simulation studies. Digest of Papers of the 2000 World Congress on Medical Physics and Biomedical Engineering and the Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, July 2000, TH-E324-04. [D]
• Vicini, P. A comparison of approximate likelihood and EM methods for population pharmacokinetic analysis. Digest of Papers of the 2000 World Congress on Medical Physics and Biomedical Engineering and the Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, July 2000, MO-E326-04. [C]
• Vicini, P. A comparison on benchmark cases of population kinetic analysis maximum likelihood and two-stage methods. Annals of Biomedical Engineering 28: Supplement 1, T-9.10, 2000. [C]
• Vicini, P. and M. J. Kushmerick. Analysis of cellular energetics by a mathematical model of biochemical energy balance: estimation of cellular parameters in human skeletal muscle. APStracts 7:0087C, 2000. [C]
• Watts DF, Barrett PHR, Chan D, Stuckey B, Martins I, Redgrave TG. Chylomicron remnant metabolism studied with a new stable isotope breath test in centrally obese subjects. Intl. Athero. Soc. Stockholm, Athero 2000. [C]

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