2002 Publications

Make a selection to see details:

• Papers
• Books and book chapters
• Abstracts

All links listed below will open in a new window. Close the new window to return to this page.

Papers

• Barrett PH, Watts GF. Shifting the LDL-receptor paradigm in familial hypercholesterolemia: novel insights from recent kinetic studies of apolipoprotein B-100 metabolism. Atheroscler Suppl. 2002 Mar;2(3):1-4. Review. [C]
• Beard DA, Liang SD, Qian H. Energy balance for analysis of complex metabolic networks. Biophys J. 2002 Jul;83(1):79-86.
• Bellazzi R, Larizza C, Montani S, Riva A, Stefanelli M, d'Annunzio G, Lorini R, Gomez EJ, Hernando E, Brugues E, Cermeno J, Corcoy R, de Leiva A, Cobelli C, Nucci G, Del Prato S, Maran A, Kilkki E, Tuominen J. A telemedicine support for diabetes management: the T-IDDM project. Comput Methods Programs Biomed. 2002 Aug;69(2):147-61. [C]
• Borradaile NM, de Dreu LE, Barrett PH, Huff MW. Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters. J Lipid Res. 2002 Sep;43(9):1544-54. [C]
• Breda E, Toffolo G, Polonsky KS, Cobelli C. Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times. Diabetes. 2002 Feb;51 Suppl 1:S227-33. [T]
• Burke J, Xu S. Complexity of a Noninterior Path-Following Method for the Linear Complementarity Problem. Journal of Optimization Theory and Applications 2002 Jan; 112 (1): 53-76.
• Burnett JR, Barrett PH. Apolipoprotein B metabolism: tracer kinetics, models, and metabolic studies. Crit Rev Clin Lab Sci. 2002;39(2):89-137. Review. [C]
• Callegari T, Caumo A, Cobelli C. Generalization of map estimation in SAAM II: validation against ADAPT II in a glucose model case study. Ann Biomed Eng. 2002 Jul-Aug;30(7):961-8. [T]
• Chan DC, Watts GF, Redgrave TG, Mori TA, Barrett PH. Apolipoprotein B-100 kinetics in visceral obesity: associations with plasma apolipoprotein C-III concentration. Metabolism. 2002 Aug;51(8):1041-6. [C]
• Chan DC, Watts GF, Barrett PH, Beilin LJ, Redgrave TG, Mori TA. Regulatory effects of HMG CoA reductase inhibitor and fish oils on apolipoprotein B-100 kinetics in insulin-resistant obese male subjects with dyslipidemia. Diabetes. 2002 Aug;51(8):2377-86. [C]
• Chan DC, Watts GF, Barrett PH, Beilin LJ, Mori TA. Effect of atorvastatin and fish oil on plasma high-sensitivity C-reactive protein concentrations in individuals with visceral obesity. Clin Chem. 2002 Jun;48(6 Pt 1):877-83. [C]
• Chan DC, Watts GF, Mori TA, Barrett PH, Beilin LJ, Redgrave TG. Factorial study of the effects of atorvastatin and fish oil on dyslipidaemia in visceral obesity. Eur J Clin Invest. 2002 Jun;32(6):429-36. [C]
• Chan DC, Watts GF, Barrett PH, Mori TA, Beilin LJ, Redgrave TG. Mechanism of action of a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor on apolipoprotein B-100 kinetics in visceral obesity. J Clin Endocrinol Metab. 2002 May;87(5):2283-9. [C]
• Chan DC, Watts GF, Barrett PH, Martins IJ, James AP, Mamo JC, Mori TA, Redgrave TG. Effect of atorvastatin on chylomicron remnant metabolism in visceral obesity: a study employing a new stable isotope breath test. J Lipid Res. 2002 May;43(5):706-12. [C]
• Chan DC, Watts GF, Barrett PH, Mamo JC, Redgrave TG. Markers of triglyceride-rich lipoprotein remnant metabolism in visceral obesity. Clin Chem. 2002 Feb;48(2):278-83. [C]
• Cohn JS, Tremblay M, Batal R, Jacques H, Veilleux L, Rodriguez C, Barrett PH, Dubreuil D, Roy M, Bernier L, Mamer O, Davignon J. Effect of atorvastatin on plasma apoE metabolism in patients with combined hyperlipidemia. J Lipid Res. 2002 Sep;43(9):1464-71. [C]
• Dalla Man C, Caumo A, Cobelli C. The oral glucose minimal model: estimation of insulin sensitivity from a meal test. IEEE Trans Biomed Eng. 2002 May;49(5):419-29. [C]
• Dane-Stewart CA, Watts GF, Mamo JC, Barrett PH, Martins IJ, Dimmitt SB, Redgrave TG. Effect of Simvastatin on markers of triglyceride-rich lipoproteins in familial hypercholesterolaemia. Eur J Clin Invest. 2002 Jul;32(7):493-9. [C]
• Davis TM, Binh TQ, Thu le TA, Long TT, Johnston W, Robertson K, Barrett PH. Glucose and lactate turnover in adults with falciparum malaria: effect of complications and antimalarial therapy. Trans R Soc Trop Med Hyg. 2002 Jul-Aug;96(4):411-7. [C]
• Dwyer KP, Barrett PH, Chan D, Foo JI, Watts GF, Croft KD. Oxazolinone derivative of leucine for GC-MS: a sensitive and robust method for stable isotope kinetic studies of lipoproteins. J Lipid Res. 2002 Feb;43(2):344-9. [C]
• Ehrmann DA, Breda E, Cavaghan MK, Bajramovic S, Imperial J, Toffolo G, Cobelli C, Polonsky KS. Insulin secretory responses to rising and falling glucose concentrations are delayed in subjects with impaired glucose tolerance. Diabetologia. 2002 Apr;45(4):509-17.
• Hoffman RP, Vicini P, Cobelli C. Comparison of insulin sensitivity and glucose effectiveness determined by the one- and two-compartment-labeled minimal model in late prepubertal children and early adolescents. Metabolism. 2002 Dec;51(12):1582-6. [C]
• Huff MW, Telford DE, Edwards JY, Burnett JR, Barrett PH, Rapp SR, Napawan N, Keller BT. Inhibition of the apical sodium-dependent bile acid transporter reduces LDL cholesterol and apoB by enhanced plasma clearance of LDL apoB. Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1884-91. [C]
• Jauregizar N, Calvo R, Suarez E, Quintana A, Raczka E, Lukas JC. Pharmacokinetics and pharmacological effect of lerisetron, a new 5-HT3 antagonist, in rats. J Pharm Sci. 2002 Jan;91(1):41-52.
• Kee P, Rye KA, Taylor JL, Barrett PH, Barter PJ. Metabolism of apoA-I as lipid-free protein or as component of discoidal and spherical reconstituted HDLs: studies in wild-type and hepatic lipase transgenic rabbits. Arterioscler Thromb Vasc Biol. 2002 Nov 1;22(11):1912-7. [C]
• Nucci G, Tessarin S, Cobelli C. A morphometric model of lung mechanics for time-domain analysis of alveolar pressures during mechanical ventilation. Ann Biomed Eng. 2002 Apr;30(4):537-45. [C]
• Olin-Lewis K, Krauss RM, La Belle M, Blanche PJ, Barrett PH, Wight TN, Chait A. ApoC-III content of apoB-containing lipoproteins is associated with binding to the vascular proteoglycan biglycan. J Lipid Res. 2002 Nov;43(11):1969-77. [C]
• Pierce CH, Chen Y, Dills RL, Kalman DA, Morgan MS. Toluene metabolites as biological indicators of exposure. Toxicol Lett. 2002 Mar 24;129(1-2):65-76. [C]
• Pillonetto G, Sparacino G, Cobelli C. Handling non-negativity in deconvolution of physiological signals: a nonlinear stochastic approach. Ann Biomed Eng. 2002 Sep;30(8):1077-87. [T]
• Pillonetto G, Sparacino G, Magni P, Bellazzi R, Cobelli C. Minimal model S(I)=0 problem in NIDDM subjects: nonzero Bayesian estimates with credible confidence intervals. Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E564-73. [T]
• Prinsen BH, Kaysen GA, Klomp LW, de Boer J, Barrett PH, Thornalley PJ, Battah S, Berger R, Rabelink TJ, der Velden MG. Idiopathic hypoalbuminemia explained by reduced synthesis rate and an increased catabolic rate. Clin Biochem. 2002 Oct;35(7):545-53. [C]
• Rashid S, Uffelman KD, Barrett PH, Lewis GF. Effect of atorvastatin on high-density lipoprotein apolipoprotein A-I production and clearance in the New Zealand white rabbit. Circulation. 2002 Dec 3;106(23):2955-60. [C]
• Rashid S, Barrett PH, Uffelman KD, Watanabe T, Adeli K, Lewis GF. Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the circulation. Arterioscler Thromb Vasc Biol. 2002 Mar 1;22(3):483-7. [C]
• Singhal P, Caumo A, Carey PE, Cobelli C, Taylor R. Regulation of endogenous glucose production after a mixed meal in type 2 diabetes. Am J Physiol Endocrinol Metab. 2002 Aug;283(2):E275-83. [C]
• Sparacino G, Milani S, Arslan E, Cobelli C. A Bayesian approach to estimate evoked potentials. Comput Methods Programs Biomed. 2002 Jun;68(3):233-48.
• Sparacino G, Shames DM, Vicini P, King JC, Cobelli C. Double isotope tracer method for measuring fractional zinc absorption: theoretical analysis. Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E679-87. [C]
• Sparacino G, Pillonetto G, Capello M, De Nicolao G, Cobelli C. WINSTODEC: a stochastic deconvolution interactive program for physiological and pharmacokinetic systems. Comput Methods Programs Biomed. 2002 Jan;67(1):67-77. [C]
• Tannock LR, Olin KL, Barrett PH, Wight TN, Chait A. Triglyceride-rich lipoproteins from subjects with type 2 diabetes do not demonstrate increased binding to biglycan, a vascular proteoglycan. J Clin Endocrinol Metab. 2002 Jan;87(1):35-40. [C]
• Triggs-Raine BL, Kirkpatrick RD, Kelly SL, Norquay LD, Cattini PA, Yamagata K, Hanley AJ, Zinman B, Harris SB, Barrett PH, Hegele RA. HNF-1alpha G319S, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an Oji-Cree community. Proc Natl Acad Sci USA. 2002 Apr 2;99(7):4614-9. [C]
• Sunehag AL, Toffolo G, Treuth MS, Butte NF, Cobelli C, Bier DM, Haymond MW. Effects of dietary macronutrient content on glucose metabolism in children. J Clin Endocrinol Metab. 2002 Nov; 87(11):5168-78. [C]
• Vicini P, Gastonguay MR, Foster DM. Model-based approaches to biomarker discovery and evaluation: a multidisciplinary integrated review. Crit Rev Biomed Eng. 2002;30(4-6):379-418. [T]
• Vicini P, Avogaro A, Spilker ME, Gallo A, Cobelli C.Epinephrine effects on insulin-glucose dynamics: the labeled IVGTT two-compartment minimal model approach. Am J Physiol Endocrinol Metab. 2002 Jul;283(1):E78-84. [C]
• Watts GF, Chan DC, Barrett PH. Adipose tissue compartments and the kinetics of very-low-density lipoprotein apolipoprotein B-100 in non-obese men. Metabolism. 2002 Sep;51(9):1206-10. [C]
• Watts GF, Barrett PH. High-density lipoprotein metabolism in familial hypercholesterolaemia: significance, mechanisms, therapy. Nutr Metab Cardiovasc Dis. 2002 Feb;12(1):36-41. [C]

[top of page]

Books and book chapters

• Parhofer K, Empen K, Barrett PHR. Effect of atorvastatin on postprandial lipoprotein metabolism in normolipidemic subjects. In Lipoprotein metabolism and atherosclerosis. Richter V, Rassoul, Reuter W, Thiery J, eds. Verlag, 2002; pp 371-377. [T]

Abstracts

• Allister EM, James AP, Mamo JCL, Barrett PHR, Soares M, Watts GF. The acute effects of insulin on chylomicron metabolism in viscerally obese and lean men. European Atherosclerosis Society, Salzburg, 2002
• Barrett PHR, Johnson AJ, Ji J, Croft K, Serone A, Loeher F, Watts GF. Differential effects of fenofibrate and atorvastatin on HDL apoAI transport and plasma apoCIII concentrations in the metabolic syndrome. Circulation Suppl. 2002; 106: II-184.
• Barrett PHR, Johnson AJ, Ji J, Croft K, Serone A, Loeher F, Watts GF. Differential effects of fenofibrate and atorvastatin on HDL apoAI transport and plasma apoCIII concentrations in the metabolic syndrome. American Heart Assoc. Chicago, 2002.
• Bies RR, Gastonguay MR, Coley KC, Kroboth PD, Pollock BG. Measuring consistency of pharmacotherapy exposure in observational clinical trials using a Cpred/Cobs ratio. AAPS PharmSci. Fall 2002
• Caumo A., Dalla Man C., Di Camillo B., Basu R., Rizza R., Toffolo G., Cobelli C. Minimal Model Indices of Peripheral and Hepatic Insulin Sensitivity from a Labelled Oral Glucose Test. Diabetes 2002 51(2): A350
• Chan DC, Watts GF, Barrett PHR, Beilin LJ, Mori TA. Effect of atorvastatin and fish oil on plasma high sensitive C-reactive protein, interleukin-6 and tumor necrosis factor-alpha levels in obese subjects. European Atherosclerosis Society, Salzburg, 2002.
• Chan DC, Watts GF, Barrett PHR, Mori TA, Beilin LJ, Redgrave TG. Combined effects of an HMGCoA reductase inhibitor and fish oil on apolipoprotein B100 kinetics in visceral obesity. European Atherosclerosis Society, Salzburg, 2002.
• Chan DC, Watts GF, Barrett PHR, Mori TA, Redgrave TG. A factorial study of the effects of atorvastatin and fish oil on chylomicron remnant metabolism studied kinetically with a breath test in obese men. European Atherosclerosis Society, Salzburg, 2002.
• Chan DC, Watts GF, Barrett PHR, O'Neill, Thompson GR. Associations between Plasma Markers of Cholesterol Homeostasis and Apolipoprotein B-100 Kinetics in the Metabolic Syndrome. 28th Annual Meeting of the Australian Atherosclerosis Society, Sydney, 2002.
• Chan DC, Watts GF, Mori TA, Barrett PHR, Redgrave TG, Beilin LJ. Randomized controlled trial of the effect of n-3 fatty acids supplementation on apolipoprotein B100 and chylomicron remnant metabolism in visceral obesity. European Atherosclerosis Society, Salzburg, 2002.
• Cohn JS, Tremblay M, Batal R, Jacques H, Veilleux L, Rodriguez C, Barrett PHR, Dubreuil D, Roy M, Bernier L, Mamer O, Davignon J. Plasma apoE production is reduced by atorvastatin treatment in patients with combined. European Atherosclerosis Society, Salzburg, 2002.
• Dalla Man C., Caumo A., Toffolo G., Cobelli C. Validation of The Oral Glucose Minimal Model. Proc. 2nd European Medical & Biological Engineering Conference, IFMBE Proc. Series Vienna, Dec 2002: 1158-1159
• Dalla Man C., Toffolo G., Cobelli C. Glucose kinetics during a meal: One vs two compartment minimal model. Proceedings of IEEE EMBS-BMES Second Joint Conference Houston TX, Oct. 2002: 2222-2223
• Geiss HC, Bremer S, Barrett PHR, Otto C, Parhofer KG. In vivo metabolism of LDL-subfractions. European Atherosclerosis Society, Salzburg, 2002.
• Gibbons PL, Batty KT, Barrett PHR, Davis TME, Ilett KF. Development of a pharmacokinetic-pharmacodynamic model of dihydroartemisinin in murine malaria. Australasian Pharmaceutical Science Association 2002 Conference, Melbourne, 2002.
• Hooker A, Kerwin WS, Spilker M, Vicini P. A new model-based approach to noninvasive measurement of plaque neovasculature in carotid atherosclerosis. Summary of 4th International Symposium on Measurement and Kinetics of In Vivo Drug Effects, 24-27 April, 2002, Noordwijkerhout, The Netherlands, Advances in Simultaneous Pharmacokinetic/Pharmacodynamic Modeling, M. Danhof, M. Karlsson and R. J. Powell, Eds., 26-27, 2002. [C]
• Hoffman RP, Vicini P, Cobelli C. Comparison of insulin sensitivity and glucose effectiveness determined by the one and two compartment labeled minimal model in late prepubertal children and early adolescents. Pediatric Research 51: 707 Part 2 Suppl. S, 2002. [C]
• Kerwin WS, Hooker AC, Vicini P, Ferguson MS, Hatsukami TS, Yuan C. Volume of neovasculature volume in carotid atherosclerosis is measured noninvasively by MRI. Circulation, Vol 106, No. 19 (Supplement II): II-524, 2002. [C]
• Nolin TD, Bies RR, Gastonguay MR, Frye RF. A model for the simultaneous description of the pharmacokinetics of chlorzoxazone and its primary metabolite 6-hydroxychlorzoxazone after a single oral dose. AAPS PharmSci- Fall 2002.
• Østerberg O, Ingwersen S, Plum A, Vicini P. Kinetics and effect on glucose disposal of human insulin and insulin aspart, an insulin analogue, from a model-based analysis of euglycemic glucose clamp studies. Diabetes 51: Supplement 2, A290: 1180, 2002. [C]
• Parhofer KG, Laubach E, Barrett PHR. Atorvastatin improves postprandial lipoprotein metabolism in hypertriglyceridemia. European Atherosclerosis Society, Salzburg, 2002.
• ParhoferKG, Laubach E, Barrett PHR. Effect of atorvastatin on postprandial lipoprotein metabolism in hypertriglyceridemia. Diabetes 2002 (51 Suppl. 2): A496
• Prinsen BHCMT, Romijn JA, Bisschop P, de Barse M, Sauerwein H, Berger R, Rabelink TJ, Barrett PHR, de Sain der Velden MGM. Endogenous cholesterol synthesis determines the rate of VLDL2 apolipoprotein B100 secretion and not VLDL1 apolipoprotein B100 secretion in humans. Circulation Suppl. 2002; 106: II-253.
• Prinsen BHCMT, Romijn JA, Bisschop P, de Barse M, Sauerwein H, Berger R, Rabelink TJ, Barrett PHR, de Sain der Velden MGM. Endogenous cholesterol synthesis determines the rate of VLDL2 apolipoprotein B100 secretion and not VLDL1 apolipoprotein B100 secretion in humans. American Heart Assoc. Chicago, 2002.
• Spilker ME, Vicini P, Ka-Loh L, Brasch RC. Extracting kinetic information from dynamic imaging protocols: a Bayesian approach to parametric image analysis. Proceedings of the Second Joint Engineering in Medicine and Biology 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society, 23-26 Oct. 2002, 2: 1092-1093, 2002.
• Vicini P, Dodds MG, Gastonguay MR. Assessing Convergence of Markov Chain Monte Carlo Simulations in Hierarchical Bayesian Models for Population Pharmacokinetics. Abstract R6238, 2002 AAPS Annual Meeting and Exposition. [C]
• Watts GF, Barrett PHR, Serone AP, Chan DC, Ji J, Croft KD, Johnson AG. Differential regulation of lipoprotein metabolism by atorvastatin and fenofibrate. European Atherosclerosis Society, Salzburg, 2002.
• Watts GF, Chan DC, Barrett PHR, O'Neil FH, Thompson GR. Effects of an HMGCoA reductase inhibitor on cholesterol absorption in obesity: Implications for the regulation of very-low-density lipoprotein B100 metabolism. European Atherosclerosis Society, Salzburg, 2002.
• Watts GF, Chan DC, Barrett PHR, O'Neill, Thompson GR. Effects of a HMG CoA Reductase Inhibitor on Cholesterol Absorption in Obesity : Implications for the Regulation of Very-Low-Density Lipoprotein B-100 Metabolism. 28th Annual Meeting of the Australian Atherosclerosis Society, Sydney, 2002.
• Whitfield AJ, Robertson K, Barrett PHR, van Bockxmeer FM, Burnett JR. A novel truncating apoB gene mutation, apoB-40.3, causing familial hypobetalipoproteinemia. 28th Annual Meeting of the Australian Atherosclerosis Society, Sydney, 2002.

[top of page]