2005 Publications

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• Books and book chapters
• Abstracts

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Papers

• Adams JC, Dills RL, Morgan MS, Kalman DA, Pierce CH. A physiologically based toxicokinetic model of inhalation exposure to xylenes in Caucasian men.
  Regul Toxicol Pharmacol. 2005 Nov;43(2):203-14. Epub 2005 Oct 5.
• Bertoldo A, Price J, Mathis C, Mason S, Holt D, Kelley C, Cobelli C, Kelley DE. Quantitative assessment of glucose transport in human skeletal muscle: dynamic positron emission tomography imaging of [O-methyl-11C]3-O-methyl-D-glucose.
  J Clin Endocrinol Metab. 2005 Mar;90(3):1752-9. Epub 2004 Dec 21.
• Bies RR, Mulsant BH, Rosen J, Huber KA, Wilson NL, Kirshner MA, Pollock BG. Population pharmacokinetics as a method to detect variable risperidone exposure in patients suffering from dementia with behavioral disturbances. Am J Geriatr Pharmacother. 2005 Jun;3(2):87-91.
• Carey PE, Gerrard J, Cline GW, Dalla Man C, English PT, Firbank MJ, Cobelli C, Taylor R. Acute inhibition of lipolysis does not affect postprandial suppression of endogenous glucose production. Am J Physiol Endocrinol Metab. 289:E941-7, 2005.
• Carpin S, Pillonetto G. Motion planning using adaptive random walks, IEEE Transactions on Robotics and Automation, 21(1). Pages 129-136, 2005
• Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH. Apolipoprotein B-100 kinetics and static plasma indices of triglyceride-rich lipoprotein metabolism in overweight men. Clin Biochem. 2005 Sep;38(9):806-12.
• Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH. Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism. Clin Chem. 2005 Mar;51(3):578-85. Epub 2005 Jan 13.
• Dalla Man C, Campioni M, Polonsky KS, Basu R, Rizza RA, Toffolo G, Cobelli C. Two-Hour Seven-Sample Oral Glucose Tolerance Test and Meal Protocol: Minimal Model Assessment of {beta}-Cell Responsivity and Insulin Sensitivity in Nondiabetic Individuals. Diabetes. 2005 Nov;54(11):3265-73.
• Dalla Man C, Caumo A, Basu R, Rizza R, Toffolo G, Cobelli C. Measurement of Selective Effect of Insulin on Glucose Disposal from Labeled Glucose Oral Test Minimal Model. Am J Physiol Endocrinol Metab. 2005 Jun 21; [Epub ahead of print]
• Dalla Man C, Yarasheski KE, Caumo A, Robertson H, Toffolo G, Polonsky KS, Cobelli C. Insulin Sensitivity by Oral Glucose Minimal Models: Validation against Clamp. Am J Physiol Endocrinol Metab. 2005 Jul 12; [Epub ahead of print]
• Dash RK, Bell BM, Kushmerick MJ, Vicini P. Estimating in vitro mitochondrial oxygen consumption during muscle contraction and recovery: a novel approach that accounts for diffusion. Ann Biomed Eng. 2005 Mar;33(3):343-55.
• Di Camillo B, Sanchez-Cabo F, Toffolo G, Nair SK, Trajanoski Z, Cobelli C. A quantization method based on threshold optimization for microarray short time series. BMC Bioinformatics. 2005 Dec 1;6 Suppl 4:S11.
• Dodds MG, Visich JE, Vicini P. Population Pharmacokinetics of Recombinant Factor XIII in Cynomolgus Monkeys. AAPS J. 2005 Oct 27;7(3):E693-703.
• Dodds MG, Hooker AC, Vicini P. Robust population pharmacokinetic experiment design. J Pharmacokinet Pharmacodyn. 2005 Feb;32(1):33-64.
• Farvid MS, Ng TW, Chan DC, Barrett PH, Watts GF. Association of adiponectin and resistin with adipose tissue compartments, insulin resistance and dyslipidaemia. Diabetes Obes Metab. 2005 Jul;7(4):406-13.
• Godara G, Cannon GW, Cannon GM Jr, Bies RR, Nelson JB, Pflug BR. Role of endothelin axis in progression to aggressive phenotype of prostate adenocarcinoma. Prostate. 2005 Mar 30; [Epub ahead of print]
• Goyens PL, Spilker ME, Zock PL, Katan MB, Mensink RP. Development of a compartmental model to quantify alpha-linolenic acid conversion after longer-term intake of multiple tracer boluses. J Lipid Res. 2005 Apr 16; [Epub ahead of print]
• Hooker A, Vicini P.
  Simultaneous population optimal design for pharmacokinetic-pharmacodynamic experiments. AAPS J. 2005 Nov 1;7(4):E759-85.
• Jenner JL, Seman LJ, Millar JS, Lamon-Fava S, Welty FK, Dolnikowski GG, Marcovina SM, Lichtenstein AH, Barrett PH, deLuca C, Schaefer EJ. The metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein (a) in human beings. Metabolism. 2005 Mar;54(3):361-9.
• Kane-Gill SL, Feng Y, Bobek MB, Bies RR, Pruchnicki MC, Dasta JF. Administration of enoxaparin by continuous infusion in a naturalistic setting: analysis of renal function and safety. J Clin Pharm Ther. 2005 Jun;30(3):207-13.
• Keenan TM, Hooker A, Spilker ME, Li N, Boggy GJ, Vicini P, Folch A. Automated identification of axonal growth cones in time-lapse image sequences. J Neurosci Methods. 2005 Sep 17; [Epub ahead of print]
• Kharasch ED, Whittington D, Hoffer C, Krudys K, Craig K, Vicini P, Sheffels P, Lalovic B. Paradoxical role of cytochrome P450 3A in the bioactivation and clinical effects of levo-alpha-acetylmethadol: importance of clinical investigations to validate in vitro drug metabolism studies. Clin Pharmacokinet. 2005;44(7):731-51.
• Krudys KM, Dodds MG, Nissen SM, Vicini P. Integrated model of hepatic and peripheral glucose regulation for estimation of endogenous glucose production during the hot IVGTT. Am J Physiol Endocrinol Metab. 2005 May;288(5):E1038-46. Epub 2005 Jan 4.
• Matthan NR, Jalbert SM, Lamon-Fava S, Dolnikowski GG, Welty FK, Barrett HR, Schaefer EJ, Lichtenstein AH. TRL, IDL, and LDL apolipoprotein B-100 and HDL apolipoprotein A-I kinetics as a function of age and menopausal status. Arterioscler Thromb Vasc Biol. 2005 Aug;25(8):1691-6.
• McDonald GB, McCune JS, Batchelder A, Cole S, Phillips B, Ren AG, Vicini P, Witherspoon R, Kalhorn TF, Slattery JT. Metabolism-based cyclophosphamide dosing for hematopoietic cell transplant. Clin Pharmacol Ther. 2005 Sep;78(3):298-308.
• Millar JS, Maugeais C, Ikewaki K, Kolansky DM, Barrett PH, Budreck EC, Boston RC, Tada N, Mochizuki S, Defesche JC, Wilson JM, Rader DJ. Complete deficiency of the low-density lipoprotein receptor is associated with increased apolipoprotein B-100 production. Arterioscler Thromb Vasc Biol. 2005 Mar;25(3):560-5. Epub 2005 Jan 6.
• Ng TW, Watts GF, Farvid MS, Chan DC, Barrett PH. Adipocytokines and VLDL metabolism: independent regulatory effects of adiponectin, insulin resistance, and fat compartments on VLDL apolipoprotein B-100 kinetics? Diabetes. 2005 Mar;54(3):795-802.
• Ng TW, Watts GF, Stuckey BG, Ching HL, Chan DC, Uchida Y, Sakai N, Yamashita S, Martins IJ, Redgrave TG, Barrett PH. Does pravastatin increase chylomicron remnant catabolism in postmenopausal women with type 2 diabetes mellitus? Clin Endocrinol (Oxf). 2005 Dec;63(6):650-6.
• Ooi EM, Watts GF, Farvid MS, Chan DC, Allen MC, Zilko SR, Barrett PH. High-density lipoprotein apolipoprotein A-I kinetics in obesity. Obes Res. 2005 Jun;13(6):1008-16.
• Pereverzev YV, Prezhdo OV, Forero M, Sokurenko EV, Thomas WE.
  The two-pathway model for the catch-slip transition in biological adhesion. Biophys J. 2005 Sep;89(3):1446-54. Epub 2005 Jun 10.
• Spilker ME, Seng KY, Yao AA, Daldrup-Link HE, Shames DM, Brasch RC, Vicini P. Mixture model approach to tumor classification based on pharmacokinetic measures of tumor permeability. J Magn Reson Imaging. 2005 Oct;22(4):549-58.
• Sunehag AL, Toffolo G, Campioni M, Bier DM, and Haymond MW. Effects of dietary macronutrient intake on insulin sensitivity and secretion and glucose and lipid metabolism in healthy, obese adolescents. J Clin Endocrinol Metab, 90:4496­502, 2005
• Telford DE, Lipson SM, Barrett PH, Sutherland BG, Edwards JY, Aebi JD, Dehmlow H, Morand OH, Huff MW. A novel inhibitor of oxidosqualene:lanosterol cyclase inhibits very low-density lipoprotein apolipoprotein B100 (apoB100) production and enhances low-density lipoprotein apoB100 catabolism through marked reduction in hepatic cholesterol content. Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2608-14.
• Thomas WE, Forero M, Yakovenko O, Nilsson L, Vicini P, Sokurenko E, Vogel V. Catch Bond Model Derived from Allostery Explains Force-Activated Bacterial Adhesion. Biophys J. 2005 Nov 4; [Epub ahead of print]
• Whitfield AJ, Barrett PH, Robertson K, Havlat MF, van Bockxmeer FM, Burnett JR. Liver dysfunction and steatosis in familial hypobetalipoproteinemia. Clin Chem. 2005 Jan;51(1):266-9. Epub 2004 Oct 28.

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Books and book chapters

• Vicini P, Bonate P. Preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development. In: "Preclinical Drug Development", D. R. Taft and M. Rogge, Eds., p. 199-220, Taylor and Francis, New York, 2005.

Abstracts

• Allister EM, JY Edwards, PHR Barrett, EE Mulvihill, MW Huff. Naringenin mimics the kinetics of insulin-induced inhibition of apoB100- containing lipoprotein assembly in HepG2 cells through a mechanism independent of the insulin receptor. Arterio Thromb Vasc Biol 2005; 25: e53.
• Barrett H, Nguyen M, Chan D, et al. Comparison of effects of fish oils and atorvastatin on HDL metabolism in obesity. Atherosclerosis Supplements 6 (1): 47-47 Apr 2005
• Basu R, Dallaman C, Campioni M, et al. The effects of age on insulin secretion and action differ in elderly men and women. Diabetes 54: A369-A370 Suppl. 1 2005
• Bovo V, Bertoldo A, Cobelli C. Impact of unmetabolized tracer function modeling on quantification of [carbonyl-11C]WAY-100635 PET images. J Cereb Blood Flow Metab 25: S630-S630
• Bovo V, Bertoldo A, Cobelli C. Binding potential underestimation with reference tissue models: Insight from [carbonyl-11C]WAY-100635 simulation studies. J Cereb Blood Flow Metab 25: S641-S641
• Campioni M, Dallaman C, Toffolo G, et al. Impact of sleep duration on diurnal glucose tolerance. Diabetes 54: A333-A333 Suppl. 1 2005
• Campioni M, Toffolo G, Spiegel K, et al. Morning to evening decrease in insulin sensitivity and beta-cell responsivity to identical meals. Diabetes 54: A333-A333 Suppl. 1 2005.
• Carey PE, Gerrard J, Cline GW, Dalla Man C, English PT, Firbank MJ, Cobelli C, Taylor R. Acute inhibition of lipolysis does not affect postprandial suppression of endogenous glucose production. Diabetolgia 48 (supp1), 2005, A221, 2005.
• Chierici M, Toffolo G, Basu R, Rizza RA, Cobelli C. Effect of age and gender on glucose production during intravenous glucose tolerance test. Diabetologia 48: A226-A226 616 Suppl. 1, 2005
• Dalla Man C, Chittlapilly E, Campioni M, Basu R, Toffolo G, Rizza RA, Cobelli C. Assessment of insulin sensitivity and beta-cell responsivity by oral minimal models: mixed meal against OGTT. Diabetologia 48: A198-A198 536 Suppl. 1, 2005
• Dalla Man C, Rizza RA, Cobelli C. A Simulation Model of the Glucose-Insulin System in Postprandial State. Proceedings  Of 1st Clinical Diabetes Technology Meeting, San Francisco, CA, April 15-16, 2005.
• Di Camillo B, Sanchez-Cabo F, Nair SK, Toffolo G, Cobelli C. Identification of gene regulatory modules using entropy and mutual information. in Proceedings of Bioinformatics Italian Society, Milan, 17-19 March 2005, Abstract 31.
• Di Camillo B, Sanchez-Cabo F, Toffolo G, Trajanoski Z, Cobelli C. Optimization of the quantization approach in reverse engineering of microarray data. In: Proceedings of European Mathematical Society Summer School 2005: Statistics in Genetics and Molecular Biology, University of Warwick, UK, 10-16 September  2005.
• Feng Y, Green B, Duffull SB, Kane SL, Bobek MB, Bies RR. Application of Monte Carlo simulations to identify an appropriate dosage strategy for patients receiving a continuous intravenous infusion of enoxaparin. Clinical Pharmacology and Therapeutics 77 (2): P88-P88 Suppl. S, Feb 2005.
• Feng Y, Pollock BG, Reynolds C, Bies RR. Paroxetine pharmacokinetics in geriatric patients. AAPS PharmSci, Abstract M1116 2005.
• Gupta D, Regnier M, Vicini P. Mathematical model selection in muscle contraction. Abstract 1173 (P5.139), BMES Annual Fall Meeting, September 28 - October 1, 2005, Baltimore, MD.
• Hooker A, Kerwin WS, Vicini P. Simultaneous population D-optimal designs for contrast enhanced MRI measurements of atherosclerotic plaque neovasculature. PAGE (Population Approach Group in Europe) Fourteenth meeting, Pamplona, Spain, 16-17 June, 2005, http://www.page-meeting.org/
• Krudys K, Greenbaum CJ, Pihoker K, Vicini P. Population Analysis Of The Oral Glucose Tolerance Test In Relatives Of Type I Diabetics: Preliminary Results. MUFPADA (Midwest Users Forum in Population Approaches to Data Analysis), Indianapolis, IN, April 28-29, 2005.
• Li J, Kimko H, Bies RR, Peck C, Su HL, McKenna K. Population pharmacodynamic modeling of zolmitriptan following administration of conventional tablets. Clin Pharmacol Ther 2005:77:2:P90
• Ooi EMM, Watts GF, Chan DC, Barrett PHR. HDL kinetics in overweight-obese subjects with stable isotopy: Relative significance of catabolism and production in determining apolipoprotein AI plasma concentration. Arterio Thromb Vasc Biol 2005; 25: e74.
• Ooi EMM, Watts GF, Barrett PHR, Clifton PM, Nestel PJ. Effects of phytosterols on lipoprotein metabolism in subjects with the metabolic syndrome. Arterio Thromb Vasc Biol 2005; 25: e75.
• Pencek RR, Bertoldo A, Kelley C, et al. PET assessment of muscle specific regulation of glucose uptake in humans. Diabetes 54: A382-A382 Suppl. 1 2005
• Pencek RR, Bertoldo A, Kelley C, et al. Dynamic PET Imaging of [O-methyl-C-11]3-O-methyl-D-Glucose: Interactions between skeletal muscle group and insulin in the control of glucose transport. Diabetes 54: A92-A92 Suppl. 1 2005
• Pillonetto G, Saccomani MP. Estimating inputs of nonlinear dynamical systems using differential algebra techniques. Proceedings of the 16th World IFAC Congress, Prague, July 3-8, 2005.
• Rea RS, Bigos K, Bies R, Capitano B, Smith R. Suboptimal aminoglycoside dosing in critically ill patients. Crit Care Med 2005;33:(Suppl)A171.
• Sanchez-Cabo F, Di Camillo B, Hackl H, Toffolo G, Cobelli C, Trajanoski Z. A reverse engineering algorithm to reconstruct gene networks from short time series expression data. In: Proceedings of European Mathematical Society Summer School 2005: Statistics in Genetics and Molecular Biology, University of Warwick, UK, September 10-16, 2005.
• Sawacha Z, Cristofori G, Donà G, Guarnieri G, Corazza S, Avogaro A, Cobelli C. A New 3d-Four Segment Markerset For  Description Of Foot And Ankle Kinematic. Book of Abstracts European Society of Movement Analysis for Adults and Children (ESMAC), Barcelona, September 22 -24, 2005, Spain.
• Sawacha Z, Cristofori G, Guarnieri G, Corazza S, Cobelli C, Avogaro A. A 3d Four Segment Anatomy Based Protocol For The Description Of Foot And Ankle Kinematics. Book of Abstract GCMAS 2005, April 6-9, 2005, Portland, Oregon, USA.
• Silber HE, Jauslin PM, Gieschke R, Frey N, Vicini P, Simonsson USH, Karlsson MO. A physiology based model for the glucose-insulin regulation in healthy volunteers and diabetic patients following intravenous glucose provocations. PAGE (Population Approach Group in Europe) Fourteenth meeting, Pamplona, Spain, 16-17 June, 2005, http://www.page-meeting.org/
• Sprecher DL, Johnson AG, Pearce G, Watts GF, Barrett PHR. Effects of a Peroxisome Proliferator Activated Receptor (PPAR) Delta Agonist on Apolipoprotein B-100 Kinetics in the Metabolic Syndrome. Circulation Suppl. 2005
• Whitfield AJ, Barrett PHR, Robertson K, Parhofer KG, van Bockxmeer FM, Burnett JR. Postprandial lipoprotein metabolism in familial hypobetalipoproteinemia due to truncated apoB variants. Arterio Thromb Vasc Biol 2005; 25: e50.
• Zanderigo F, Sparacino G, Kovatchev B, Cobelli C. Glucose Prediction Algorithms from Continuous Monitoring Data: Assessment of Accuracy via Continuous Glucose-Error Grid Analysis (CG-EGA). Proceedings of Diabetes Technology Meeting 2005. November 10-12, 2005, San Francisco, California, USA.