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2006 Publications

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Papers

Books and book chapters

  • Bellazzi R, Bicciato S, Cobelli C, Di Camillo B, Ferrazzi F, Magni P, Sacchi L, Toffolo G. Analisi di dati di DNA microarray: fondamenti, selezione di geni, classificazione. Cerrutti S., Marchesi C, Eds. Metodi avanzati di elaborazione di segnali biomedici. (vol. 23, pp. 393-412). BOLOGNA: Pàtron (ITALY, 2004), pg. 393-412.
  • Bellazzi R, Bicciato S, Cobelli C, Di Camillo B, Ferrazzi F, Magni P, Sacchi L, Toffolo G. Analisi di dati di DNA microarray: reti di regolazione. Cerrutti S., Marchesi C, Eds. Metodi avanzati di elaborazione di segnali biomedici. (vol. 23, pp. 413-429). BOLOGNA: Pàtron (ITALY, 2004), pg. 413-429.
  • Vicini P. Pharmacokinetics and Pharmacodynamics. In: "Encyclopedia of Medical Devices and Instrumentation", Second Edition, J. G. Webster (Ed.), p. 269-278, Wiley-Interscience, Hoboken, 2006.
  • Vicini P. Bridging preclinical and clinical development: disease progression modeling in translational research. In: Dose Optimization in Drug Development, R. Krishna (Ed.), p. 15-33, Taylor and Francis Informa Healthcare, 2006.
  • Vicini P. Computer simulations in pharmacokinetics and pharmacodynamics: rediscovering systems physiology in the 21st century. In: Computer Applications in Pharmaceutical Research and Development, S. Ekins (Ed.), p. 513-528, John Wiley and Sons, 2006.

Abstracts

  • Akhavan A, Guruli G, McHugh K, Bies RR, Reddy ST, Nelson JB, Pflug BR. Combination atrasentan-taxane therapy for treatment of prostate cancer in-vitro and in-vivo.  American Urological Association Annual meeting, May 2006, Atlanta USA (abstract #817).
  • Barrett PHR, Nguyen MN, Chan DC, Watts GF. Comparison of the effects of fish oils and atorvastatin on apoCIII metabolism in obesity. International Atherosclerosis Society Meeting, Rome, 2006
  • Bender G, Gosset J, DeJongh J, Bies R, Danhof M.  Simulations to guide mechanism based PK-PD modeling of a synergistic interaction in an animal model of neuropathic pain.  Leiden Amsterdam Center for Drug Research Quadrennial meeting on In-Vivo and In-Vitro Measurement and Modeling of Pharmacodynamics.  Noordwijkerhout, Netherlands, April 26-29, 2006.
  • Bertoldo A, Pietra L, Moresco R.M., Panzacchi A, Gilardi M.G., Matarrese M., Turolla E., Fazio F., Cobelli C. Quantitative in vivo imaging of microglia activation using [11C]PK11195 and two reference tissue models. Proceedings of the NRM06 - 6th Neuroreceptor Mapping Symposium, Copenhagen, Denmark, July 6-8, 2006.
  • Bertoldo A, Vicini P, Cobelli C. The glucose minimal model: population vs individual parameter estimation. 6th IFAC Symposium on Modelling and Control in Biomedical Systems (Including Biological Systems), Reims - France, September 20-22, 2006.
  • Bigos K, Pollock BG, Coley KC,  Marder S, Miller D, Kirshner M, Bies RR. Sources of Variability in Olanzapine Exposure from the CATIE study.  Society for Biological Psychiatry Annual meeting May 2006, Toronto, Canada.
  • Bock G, Dalla Man C, Chittilapilly E, Campioni M, Basu R, Toffolo G, Cobelli C, Rizza R. The ability of non-glucose nutrients to modulate postprandial insulin and glucagon secretion is intact in people with pre-diabetes. Diabetologia, 49 (suppl. 1), 2006
  • Bock GM, Dalla Man C, Campioni C, Chittlapilly E, Basu R, Toffolo G, Cobelli C, Rizza RA. Does the pathogenesis of fasting and postprandial hyperglicemia differ in people with prediabetes? Diabetes, 55 (suppl. 1), 2006.
  • Bovo V, Bertoldo A, Cobelli C, Price JC. Comparison of Parametric Imaging Methods for [11C]-DASB Serotonin Transporter Binding Studies. Proceedings of the NRM06 - 6th Neuroreceptor Mapping Symposium, Copenhagen, Denmark, July 6-8, 2006.
  • Bovo V, Bertoldo A, Cobelli C, Price JC. Parametric Images of [11C]-DASB Binding to Serotonin Transporters by Generalized Weighted Linear Least Squares. Proceedings of the 12th Annual Meeting of the Human Brain Mapping, Florence, Italy, June 11-15, 2006.
  • Brehm A, Krssak M, Anderwald C, Bernroider E, Shulman GI, Dalla Man C, Cobelli C, Nowotny P, Waldhäusl W, Roden M. Hepatic glycogen storage in type 2 diabetes mellitus after a standard meal. Acta Med Aust 30, Suppl. 60: p8
  • Chan DC, Watts GF, Nguyen MN, Barrett PHR. Effects of fish oils and atorvastatin on the kinetics of HDL apoAI and apoAII in men with visceral obesity. International Atherosclerosis Society Meeting, Rome, 2006
  • Chew ML, Bies RR. Anticholinergic Activity of 107 Common Medications.  AAPS Annual Meeting, San Antonio TX, November 2006.
  • Chew ML, Pollock BG, Coley KC, Marder S, Miller D, Kirshner M, Bies RR. Sources of variability in quetiapine exposure from the CATIE study.  Society for Biological Psychiatry Annual Meeting May 2006, Toronto, Canada.
  • Chierici M, Pillonetto G, Toffolo G, Cobelli C. Glucose production by deconvolution in intravenous and oral glucose tolerance tests: role of output variable. Trans. of 28th annual international conference of IEEE Engineering in Medicine and Biology Society
  • Cohen O, Basu R, Dalla Man C, Campioni M, Bock G, Basu A, Toffolo G, Cobelli C, Rizza RA. How accurately do fasting and 2 hour glucose concentrations alone or with more complex measurements of body composition and function predict postprandial glycemic exposure? Diabetes, 55 (suppl. 1), 2006.
  • Denti P, Bertoldo A., Vicini P, Cobelli C. Identification of IVGTT minimal glucose model by nonlinear mixed-effects approaches. Proceedings of the 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS), New York City, USA, August 30 to September 3, 2006.
  • Di Camillo B, Jurman G, Merler S, Toffolo G, Cobelli C, Furlanello C. Function-based discovery of temporal patterns and regulatory modules from high throughput gene expression data. International Conference on Computational Methods in Systems Biology. The Microsoft Research - University of Trento, Centre for Computational and Systems Biology. 18 and 19 October 2006  TRENTO - ITALY
  • Di Camillo B, Toffolo G, Cobelli C. A gene network simulator integrating Boolean regulation in a continuous dynamic model. 5th European Conference on Computational Biology - ECCB '06 Eilat, Israel, September 10-13, 2006
  • Di Camillo B, Toffolo G, Cobelli C. Importance of integration in modeling dynamic data of gene expression. Biobanks for functional genomics: integrating data, integrating models. March 7-8, 2006, ITC-irst Trento.
  • Di Camillo B, Toffolo G, Nair SK, Cobelli C. Significance analysis of microarray transcript levels in time-series experiments. in Proceedings of Bioinformatics Italian Society, Bologna 28-29 April 2006, abstract n° 44.
  • Facchinetti A, Sparacino G, Zanderigo F, Cobelli C. Prediction of Glucose Concentration from CGM Data through AR Time-Series Models: Role of Sampling Frequency and Other Design Variables". Proceedings of Diabetes Technology Meeting 2006. November 2006 Atlanta, Georgia, USA.
  • Facchinetti A, Sparacino G, Zanderigo F, Cobelli C. Reconstructing by Deconvolution Plasma from Continuous Monitoring Sensor Glucose: Domain of Validity of a Plasma-Interstitium Compartmental Model. Proceedings of EMBS 2006. New York, USA, 30 August-3 September 2006.
  • Feng Y, Gastonguay MR, Pollock BG, Frank E, Kepple G, Bies RR.  The impact of the concentration near or below the limit of quantitation on the model estimation/prediction efficiency.  AAPS Annual Meeting, San Antonio TX, November 2006.
  • Feng Y, Pollock BG, Coley KC, Marder S, Miller D, Kirshner M, Bies RR. Assessing sources of variability in risperidone pharmacokinetics: a population analysis of risperidone using sparse concentration sampling from the CATIE study.  Society for Biological Psychiatry Annual meeting May 2006, Toronto, Canada.
  • Florea I, Bertoldo A, Pietra L, Moresco RM, Carpinelli A, Panzacchi A, Garibotto V, Perani D, Gilardi MC, Fazio F, Cobelli C. Kinetic analysis of [11C]MP4A for measurement of cerebral acetylcholine esterase activity without arterial blood sampling. Proceedings of the NRM06 - 6th Neuroreceptor Mapping Symposium, Copenhagen, Denmark, July 6-8, 2006.
  • Ji J, Watts GF, Johnson AG, Chan DC, Ooi EMM, Rye KA, Serone AP, Barrett PHR. High density lipoprotein transport in the metabolic syndrome: application of a new model for HDL particle kinetics. International Atherosclerosis Society Meeting, Rome, 2006
  • Ji J, Barrett PHR, Johnson AG, Chan DC, Serone AP, Rye KA, Watts GF. Lipid transfer proteins and apolipoprotein B-100 metabolism in the metabolic syndrome treated with fenofibrate. International Atherosclerosis Society Meeting, Rome, 2006.
  • Nguyen MN, Chan DC, Watts GF, Barrett PHR. Use of Intralipid for kinetic analysis of HDL apoCIII: evidence for a homogeneous kinetic pool of apoCIII in plasma. International Atherosclerosis Society Meeting, Rome, 2006.
  • Ooi EMM, Watts GF, Ji J, Rye KA, Johnson AG, Chan DC, Serone AP, Barrett PHR. Role of plasma phospholipid transfer protein activity in determining HDL kinetics in vivo. International Atherosclerosis Society Meeting, Rome, 2006.
  • Ooi EMM, Watts GF, Ji J, Rye KA, Johnson AG, Chan DC, Serone AP, Barrett PHR. Balancing feedback and lipoprotein transport in the metabolic syndrome. International Atherosclerosis Society Meeting, Rome, 2006.
  • Peruzzo D, Bertoldo A, Zanderigo F, Cobelli C. Automatic selection of arterial input function on dynamic contrast-enhanced MRI images: comparison of different methods. Proceedings of the 14th Scientific Meeting& Exhibition of the International Society for Magnetic Resonance in Medicine, Seattle, WA, USA, 6-12 May 2006.
  • Telford DE, Sutherland BG, Edwards JY, Andrews JD, Barrett PHR, Huff MW. The Molecular Mechanisms For The Reduction Of LDL ApoB100 By Ezetimibe Plus Simvastatin Involve Enhanced LDL ApoB100 Clearance Mediated By A Synergistic Increase In Hepatic Expression Of LDL Receptors. Atherosclerosis, Thrombosis and Vascular Biology Meeting, Denver, 2006
  • Telford DE, Sutherland BG, Edwards JY, Andrews JD, Barrett PHR, Huff MW. Ezetimibe plus Simvastatin decreases LDL apolipoprotein B via enhanced clearance mediated by increased hepatic expression of LDL receptors. Atherosclerosis, Thrombosis and Vascular Biology Meeting, Denver, 2006
  • Tomasi G, Bertoldo A, Cobelli C. Parametric imaging of [11C]MP4A: comparison of different methods on simulated data. Neuroreceptor Mapping 2006, Copenhagen, Denmark
  • Tomasi G, Bertoldo A, Cobelli C. Parametric imaging of acetylcholinesterase activity with PET: evaluation of different methods. 6th IFAC Symposium on Modelling and Control in Biomedical Systems (Including Biological Systems), Reims - France, September 20-22, 2006.
  • Tomasi G, Bertoldo A, Cobelli C. Parametric Imaging Of Acetylcholinesterase Activity With Pet: Evaluation Of Different Methods. IFAC MCBMS 2006, Reims, France.
  • Tomasi G, Bertoldo A, Fazio F, Cobelli C. Parametric imaging of [11C]MP4A: comparison of different methods on simulated data. Proceedings of the NRM06 - 6th Neuroreceptor Mapping Symposium, Copenhagen, Denmark, July 6-8, 2006.
  • Tortorici MA, Kochanek PM, Bies RR, Venkataramanan R, Poloyac SM. Mild and moderate hypothermia alters CYP2E1 and CYP3A4 enzyme kinetics in human hepatic microsomes.  AAPS Annual Meeting, San Antonio TX, November 2006.
  • Vicini P. The population approach identity crisis: the search for innovation in modeling and simulation. PAGE 15 (2006) Abstr 942 [http://www.page-meeting.org/?abstract=942]
  • Zanderigo F, Bertoldo A, Pillonetto G, Cobelli C. Detection of dispersion from bolus-tracking MRI improves cerebral blood flow quantification: a simulation study. Proceedings of the 14th Scientific Meeting & Exhibition of the International Society for Magnetic Resonance in Medicine, Seattle, WA, USA, 6-12 May 2006.
   
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