Datasets

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• acknowledge the Resource Facility for Population Kinetics at http://www.rfpk.washington.edu
• acknowledge National Institutes of Health grant EB-01975

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Please note that the data are provided "as is" as a service to the research community and no representation is made by anyone of their accuracy, correctness or suitability for any particular use.

Aarons L, Vozeh S, Wenk M, Weiss P, Follath F. Population pharmacokinetics of tobramycin. Br J Clin Pharmacol. 1989 Sep;28(3):305-14: Population pharmacokinetics of tobramycin.

Best NG, Tan KK, Gilks WR, Spiegelhalter DJ. Estimation of population pharmacokinetics using the Gibbs sampler. J Pharmacokinet Biopharm. 1995 Aug;23(4):407-35: Neonatal pharmacokinetics of gentamicin (randomly subsampled from Thomson et al., 1988)

Cobelli C, Toffolo G, Ferrannini E. A model of glucose kinetics and their control by insulin: compartmental and noncompartmental approaches. Math Biosci 72: 291-315, 1984. Tracer glucose kinetics during basal state and euglycemic clamp

Grasela TH Jr, Donn SM. Neonatal population pharmacokinetics of phenobarbital derived from routine clinical data. Dev Pharmacol Ther. 1985;8(6):374-83: Neonatal pharmacokinetics of phenobarbital

Holford N, Black P, Couch R, Kennedy J, Briant R. Theophylline target concentration in severe airways obstruction - 10 or 20 mg/L? A randomised concentration-controlled trial. Clin Pharmacokinet. 1993 Dec;25(6):495-505: Theophylline treatment for severe airway obstruction

Kataria BK, Ved SA, Nicodemus HF, Hoy GR, Lea D, Dubois MY, Mandema JW, Shafer SL. The pharmacokinetics of propofol in children using three different data analysis approaches. Anesthesiology. 1994 Jan;80(1):104-22: Pharmacokinetics of propofol in children

Saccomani MP, Bonadonna RC, Caveggion E, DeFronzo RA, Cobelli C. Bicarbonate kinetics in humans: identification and validation of a three-compartment model. Am J Physiol. 1995 Jul;269(1 Pt 1):E183-92. Data from impulse-dose studies of labeled bicarbonate in healthy subjects

Sparacino G, Tombolato C, Cobelli C. Maximum-likelihood versus maximum a posteriori parameter estimation of physiological system models: the C-peptide impulse response case study. IEEE Trans Biomed Eng. 2000 Jun;47(6):801-11. Biosynthetic C-peptide kinetics in steady state

Thomson AH, Way S, Bryson SM, McGovern EM, Kelman AW, Whiting B. Population pharmacokinetics of gentamicin in neonates. Dev Pharmacol Ther. 1988;11(3):173-9: Neonatal pharmacokinetics of gentamicin (whole)

Upton RA, Thiercelin JF, Guentert TW, Wallace SM, Powell JR, Sansom L, Riegelman S. Intraindividual variability in theophylline pharmacokinetics: statistical verification in 39 of 60 healthy young adults. J Pharmacokinet Biopharm. 1982 Apr;10(2):123-34: Oral pharmacokinetics of theophylline

Verme CN, Ludden TM, Clementi WA, Harris SC. Pharmacokinetics of quinidine in male patients. A population analysis. Clin Pharmacokinet. 1992 Jun;22(6):468-80: Oral pharmacokinetics of quinidine

Vicini P, Caumo A, Cobelli C. The hot IVGTT two-compartment minimal model: indexes of glucose effectiveness and insulin sensitivity. Am J Physiol. 1997 Nov;273(5 Pt 1):E1024-32. Labeled Standard Intravenous Glucose Tolerance Test.

Vicini P, Cobelli C. The iterative two-stage population approach to IVGTT minimal modeling: improved precision with reduced sampling. Am J Physiol Endocrinol Metab. 2001 Jan;280(1):E179-86. Glucose and insulin during a standard intravenous glucose tolerance test in healthy adults

Vicini P, Zachwieja JJ, Yarasheski KE, Bier DM, Caumo A, Cobelli C. Glucose production during an IVGTT by deconvolution: validation with the tracer-to-tracee clamp technique. Am J Physiol. 1999 Feb;276(2 Pt 1):E285-94. Glucose, tracer glucose and insulin during an insulin-modified intravenous glucose tolerance test in normal adults

Wakefield JC, Smith AFM, Racine-Poon A, Gelfand AE. Bayesian analysis of linear and non-linear population models by using the Gibbs sampler. Applied Statistics 43(1): 201-221, 1994: Pharmacokinetics of cadralazine in cardiac failure patients