Tutorials

Accessing Tutorials:

In order to access the tutorials on individual and population kinetics developed at RFPK, you will need to fill out a short questionaire.

• Click on the tutorial title or PDF from the list below.
  Fill out the form.
• Click the submit button and you will have access to the complete tutorial or PDF.
• Each request requires filling out a form.

Select Tutorials:

• An Introduction to Bayesian Forecasting
  Print tutorial (126K PDF*)
  
  
• Basic Population PK-PD
  Print tutorial (371K PDF*)
  
  
• Design and Analysis of Modeling Studies: A Short Course Using the SAAM II Software System
  • part 1: Fundamentals
    Print tutorial (262K PDF*)
  • part 2: Creating Structural System Models
    Print tutorial (467K PDF*)
  • part 3: Model Identifiability
    Print tutorial (126K PDF*)
  • part 4: Fitting Models to Data: Parameter Estimation
    Print tutorial (355K PDF*)
  • part 5: Algebraic and Noncompartmental Models
    Print tutorial (492K PDF*)
  • part 6: Complex Modeling Issues
    Print tutorial (473K PDF*)
  • part 7: Pharmacokinetic and Metabolic Examples
    Print tutorial (566K PDF*)
  • part 8: Advanced Modeling Tools
    Print tutorial (325K PDF*)
  
  
• The SAAM II Minimal Models: A Library of Models of Glucose-Insulin Regulation (760 K PDF*)
  
  
• Improving Clinical Trial Design Via Simulation and Estimation Methods (292K PDF*) [No form required.]
  • Module 1: Background (175K PDF*)
  • Module 2: Methods (716K PDF*)
  • Module 3: Real World Examples of CTS (383K PDF*)
  • Module 4: Planning a Simulation Project (108K PDF*)
  
  
• Physiologically-based kinetic modeling: a tool to understand where drugs and poisons go, and how quickly they get there.
  
  
• Toxicokinetic Modeling:
  • Basic Toxicokinetics
  • Compartmental and Physiologic Modeling in Toxicology and Risk Assessment
  • Population Kinetic Modeling in Toxicology and Risk Assessment

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