Faculty
Mart Mannik, M.D.
Emeritus Professor of Medicine
Division of Rheumatology
1967-2001 Head, Division of Rheumatology
EDUCATION AND TRAINING
M.D., Western Reserve University School of Medicine, Cleveland, OH, 1959
Residency in Medicine, Massachusetts General Hospital, Boston, MA, 1959-61
Guest Investigator at the Rockefeller University and Assistant Physician to the Hospital of the Rockefeller, New York, NY, 1961-63
Clinical Associate at the National Institute of Arthritis and Metabolic Diseases, Rheumatology Branch, Bethesda, MD, 1963-65
PREVIOUS RESEARCH INTERESTS
The study of autoantibodies involved in development of renal disease in patients with systemic lupus erythematosus. The investigation of autoantibodies that contribute to the inflammation in joints of patients with rheumatoid arthritis.
REPRESENTATIVE PUBLICATIONS
Mannik M, Merrill CE, Stamps LD, Wener MH. Multiple autoantibodies form the glomerular immune deposits in patients with systemic lupus erythematosus. J Rheumatol 30; 1495-1504:2003.
Mannik M, Merrill CE, Wener MH. Antibodies to human myeloperoxidase in glomerular immune deposits of systemic lupus erythematosus. Lupus 9; 607-613: 2000.
Mannik M, Wener MH. Antibodies to the collagen-like region of C1q are deposited in renal glomeruli of patients with proliferative lupus glomerulonephritis. Arthritis Rheum 40;1504-1511:1997.
Mannik M, Kapil S, Merrill CM. In patients with rheumatoid arthritis IgG binding to denatured collagen type II is in part mediated by IgG-fibronectin complexes. J Immunol 158;1446-1452:1997.
Mannik M. Presence of covalent bonds between immune deposits and other macromolecules in murine renal glomeruli. Clin Exp Immunol 103;285-288:1996.
Mannik M, Person RE. Deep penetration of antibodies into the articular cartilage of patients with rheumatoid arthritis. Rheumatol Int 14;95-102:1994