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Division of Rheumatology
1959 NE Pacific St
Health Science Bldg BB561
Campus Box 356428
Seattle, WA 98195

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Phone: 206-543-3414

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Mart Mannik, M.D.


Emeritus Professor of Medicine
Division of Rheumatology
1967-2001 Head

Division of Rheumatology

1959 NE Pacific Street
Box 356428
Seattle, WA 98195-6428
Phone: 206-543-3414
Fax: 206-685-9397




  • M.D., Western Reserve University School of Medicine, Cleveland, OH, 1959
  • Residency in Medicine, Massachusetts General Hospital, Boston, MA, 1959-61
  • Guest Investigator at the Rockefeller University and Assistant Physician to the Hospital of the Rockefeller, New York, NY, 1961-63
  • Clinical Associate at the National Institute of Arthritis and Metabolic Diseases, Rheumatology Branch, Bethesda, MD, 1963-65




The study of autoantibodies involved in development of renal disease in patients with systemic lupus erythematosus. The investigation of autoantibodies that contribute to the inflammation in joints of patients with rheumatoid arthritis.





Mannik M, Merrill CE, Stamps LD, Wener MH. Multiple autoantibodies form the glomerular immune deposits in patients with systemic lupus erythematosus. J Rheumatol 30; 1495-1504:2003.

Kohro-kawata J, Wener MH, Mannik M. The effect of high salt concentration on detection of serum immune complexes and autoantibodies to C1q in patients with systemic lupus erythematosus. J Rheumatol. 2002 Jan;29(1)84-9.

D'Arcy CA, Mannik M. Serum sickness secondary to treatment with the murine-human chimeric antibody IDEC-C2B8 (Rutuximah). Arthritis Rhem 44;1717-8: 2001.

Mannik M, Merrill CE, Wener MH. Antibodies to human myeloperoxidase in glomerular immune deposits of systemic lupus erythematosus. Lupus 9; 607-613: 2000.

Mannik M, Wener MH. Antibodies to the collagen-like region of C1q are deposited in renal glomeruli of patients with proliferative lupus glomerulonephritis. Arthritis Rheum 40;1504-1511:1997.

Mannik M, Kapil S, Merrill CM. In patients with rheumatoid arthritis IgG binding to denatured collagen type II is in part mediated by IgG-fibronectin complexes. J Immunol 158;1446-1452:1997.

Mannik M. Presence of covalent bonds between immune deposits and other macromolecules in murine renal glomeruli. Clin Exp Immunol 103;285-288:1996.

Mannik M, Person RE. Deep penetration of antibodies into the articular cartilage of patients with rheumatoid arthritis. Rheumatol Int 14;95-102:1994



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