Faculty
Gordon A. Starkebaum, M.D.
Professor of Medicine
Division of Rheumatology
Rheumatology Section Head
VA Puget Sound Health Care System
Associate Dean
OFFICE ADDRESS
VA Puget Sound Health Care System
1660 South Columbian Way
Box 358280
Seattle, WA 98108
gasl@u.washington.edu
Telephone: (206) 764-2260
FAX (206) 764-2250
EDUCATION AND TRAINING
M.D., Columbia University College of Physicians and Surgeons, New York, NY, 1970
Rotating Internship, Harborview Medical Center, Seattle, WA, 1970-71
Residency in Medicine, University of Washington, Seattle, WA, 1973-75
Fellowship in Rheumatology, University of Washington, Seattle, WA, 1975-77
CURRENT RESEARCH INTERESTS
Proliferation of large granular lymphocytes in patients with rheumatoid arthritis and Felty’s syndrome.
Evaluation and treatment of immune-mediated neutropenia.
Role of hepatitis C in rheumatic disease.
REPRESENTATIVE PUBLICATIONS
Starkebaum G, Price TH, Lee MY, Arend WP: Autoimmune neutropenia in systemic lupus erythematosus. Arthritis Rheum 21:504-512, 1978.
Loughran TP, Kadin ME, Starkebaum G, Abkowitz JL, Clark EA, Disteche C, Lum G, Slichter SJ: Leukemia of large granular lymphocytes: association with clonal chromosomal abnormalities and autoimmune neutropenia, thrombocytopenia and hemolytic anemia. Ann Intern Med 102:169-175, 1985.
Starkebaum G, Harlan JM: Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine. J Clin Invest 77:1370-1376, 1986.
Loughran TP Jr, Starkebaum: Large granular lymphocyte leukemia: report of 38 cases and review of the literature. Medicine 66:397-405, 1987.
Loughran TP, Starkebaum G, Kidd P, Nieman P: Clonal proliferation of large granular lymphocytes in rheumatoid arthritis. Arthritis Rheum 31:31-36, 1988.
Loughran TP Jr, Kidd PG, Starkebaum G. Sustained improvement of large granular lymphocyte leukemia treated with low-dose methotrexate. Blood 84:2164-2170, 1994.
Davey MP, Starkebaum G, Loughran TP Jr: CD3+ leukemic large granular lymphocytes utilize diverse T-cell receptor Vb genes. Blood 85:146-150, 1995.
Starkebaum G, Loughran TP Jr, Gaur LK, Davis P, Nepom BS. Immunogenetic similarities between patients with Felty's syndrome and those with clonal expansions of large granular lymphocytes in rheumatoid arthritis. Arthritis Rheum 40:624-626, 1997.
Dawson TM, Starkebaum G, Wood BL, Willkens RF, Gown AM. Epstein-Barr virus, methotrexate and lymphoma in patients with rheumatoid arthritis and primary Sjögren’s Syndrome – a case series. J Rheumatol 28:47-53, 2001
Starkebaum G. Rheumatoid arthritis, methotrexate, and lymphoma: risk substitution, or cat and mouse with Epstein-Barr virus? [editorial] J Rheumatol 28:2573-5, 2001.
Hsu FC, Starkebaum G, Boyko EJ, Dominitz JA. Prevalence of rheumatoid arthritis and hepatitis C in those age 60 and older in a US population based study. J Rheumatol 30:455–8, 2003.
Starkebaum G, Sasso EH. Hepatitis C and B Cells: Induction of autoimmunity and lymphoproliferation may reflect chronic stimulation through cell-surface receptors. [editorial] J Rheumatol 31:416-18, 2004.
Starkebaum G. Rheumatoid arthritis and lymphoma: risky business for B cells. J Rheumatol 2007; 34:243-6.