Recent News & Events

 

 

Lucrezia Colonna Awarded 2015 Perkins Coie Award

Dr. Lucrezia Colonna, PhD and Researcher with the Elkon Lab, has been selected as the recipient of the 2015 Perkins Coie Award for Discovery. Her project “Investigating the Protective Role of Intracellular Complement C3 in the Prevention of Lupus Autoimmunity.” The Perkins Coie Discovery Grants have supported translational research at the UW since 2007.

 

You can find out more about the Elkon Lab and the Divsion's Publications on our website.

 

Dr. Grant Hughes named Fellowship Program Director & Associate Professor

 

The Division of Rheumatology is excited to announce that Dr. Grant Hughes has been promoted to the position of Associate Professor and Fellowship Program Director. Dr. Hughes was a Fellow with the Division from 2003-2005 and was an Assistant Professor from 2005-2009. You can find more information about the Fellowship Program here.

 

Dr. Gregory Gardner served as Fellowship Program Director for over 10 years. The Fellowship program benefited greatly from his leadership and will continue to as Dr. Gardner will be acting Associate Program Director.

 

 

In Memoriam: Dr. Louis Healey

The Division of Rheumatology is sad to annouce the passing of Dr. Louis Healey. Dr. Peter SImkin, Professor Emeritus, describes his career with and contributions to the Division of Rheumatology below.

 

"Dr. Louis Healey died at home during the week after Christmas, 2014.

 

Dr. Healey, known as Andy interned in Medicine at King County Hospital (now Harborview), returned to his native New York for training in Rheumatology, and then practiced briefly on Long Island before John Decker recruited him to join the faculty of the University of Washington.  Here, he confirmed the hypothesis that “Filipino Hyperuricemia” represents a genetic defect in the renal transport of uric acid but becomes pathologic only when its bearers adopt a Western diet.  He also began his career-long interest in the paired problems of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA).  He was a well-respected  teacher and student of joint diseases who at times was the only clinician on the faculty.


In 1969, he left the University to enter practice at the Virginia Mason Clinic.  There, with his practice partner Ken Wilske, Andy continued his studies of PMR and GCA and developed the concept of “inverting the pyramid” to treat rheumatoid arthritis. This concept of a “step down bridge” is still seen as a landmark change to a more aggressive regimen aimed at the target of full remission in early disease.

 

Andy was a prolific writer. The US National Library of Medicine currently cites 138 contributions to him. His papers reflect incisive thought, sparing use of the English language, and a quick sense of humor.  These qualities served him well during the 6 years he served as editor of the King County Medical Society Bulletin in the early 1970’s.
Throughout his years in private practice, Andy remained a valued contributor on the clinical faculty of the University of Washington where he ultimately became Clinical Professor Emeritus.  His work was recognized nationally by the American College of Rheumatology which first named him a Master Clinician and later went on to give him its Distinguished Clinician Scholar award in 1991."

 

 

Elkon Lab Awarded Multiple Grants

Dr. Elkon, Professor & Division Head, has been awarded multiple grants to support his research.

 

  • A NIH R21 for his project: “Mechanisms of Ultraviolet Inflammation in Lupus”.  This project received funding for 2 years.
  • A Royalty Research Fund for his project "Association between Type I Interferons and Systemic Lupus Erythematosus" This project will be funded for 2 years.
  • An Alliance for Lupus Research for the project researching "The cyclic GAMP pathway in SLE" This project will be funded 3 years.
  • A NIH R01 for the project "Innate Immune Response to Hepatocyte Death". Dr. Elkon will be Co-Investigator on this project working with Dr. Nicholas Crispe. The project recieved funding for 5 years.

 

You can find more information on the Elkon Lab here.

 

2015 ACGME Rheumatology Fellows

We are excited to announce our 2015 ACGME Fellows.

 

Dr. Hsin-Hsuan Juo.

Dr. Juo will join us from Fu Jen Catholic University School of Medicine in Taiwan. She completed her residency at Danbury Hospital in Danbury, CT.

 

Dr. Jeonghun Moon.

Dr. Moon will join us from Yonsei University, Wonju College of Medicine in the Republic of Korea. He completed his residency at the Albert Einstein College of Medicine in New York City, NY.

 

 

Dr. Jenna Thomason.

Dr. Thomason will join us from the Emory University School of Medicine. She completed her residency at the University of Washington in Seattle, WA.

 

You can learn more about our Fellowship Program here.

 

March 2015 Visiting Speakers

In March 2015 the Division of Rheumatology will be hosting multiple visiting speakers.

 

On Monday March 9th, Dr. Erika Noss will visit from Harvard Medical School & Brigham and Women's Hospital. She will present "Joint Fibroblast Function in Rheumatoid Arthritis: Tales of SNPs & Cadherin". Please note that Dr. Noss's presentation will take place at the South Lake Union campus.

 

On Tuesday March 31st, Dr. Daniel Furst will visit from the University of California, Los Angeles. He will present on "GI Complications in Systemic Sclerosis". Dr. Furst's presentation will take place in the Health Sciences Building, Room RR-110.

 

 

You can find presentation times and more information on our Rheumatology Conferences page.

 

 

Dr. John Stone- 2015 Lane Lecture Speaker

 
Dr. John Stone was the 2015 Lane Lecture speaker. He is currently the Director of Clinical Rheumatology at Massachusetts General Hospital.

Dr. Stone spoke at the Lane Lecture & Reception on March 5th regarding Updates on IGG4 Disease. On March 5th he also presented at the UW Department of Medicine Grand Rounds as well as a Rheumatology specific conference talk.

You can view pictures from the 2015 Lane Lecture & Reception here. You can also find Dr. Stone's Lecture on the Department of Medicine's YouTube site.

 

February 2015 Visiting Speakers

 

In February 2015 the Division of Rheumatology will be hosting multiple visiting speakers.

 

On Friday February 13th, Dr. Una Makris will visit from the University of Texas, Southwestern. She wil present "Back Pain In Older Adults: A Quantitative & Qualitative Perspective".

 

On Tuesday February 17th Dr. Laura Durcan will visit from John Hopkins. She will present "Hydoxychloriquine Blood Levels in Systemic Lupus Erythematosus: How Measurement Improves Adherence".

 

On Tuesday February 24th, Dr. James Andrews will visit from the University of California at San Francisco. He will present on "Muscle Strength, Body Composition, and Physical Disability in SLE".

 

All presentations will take place in the UW Health Sciences Building in room RR-110. You can find presentation times and more information on our Rheumatology Conferences page.

 

Rheumatology Research Foundation - Paula de Merieux Fellowship Training Award

 

RRF Logo

 

The UW Division of Rheumatology is proud to announce our division has been awarded the Paula de Merieux Fellowship Training Award by the Rheumatology Research Foundation. This Award is to provide support to an underrepresented minority or female fellow in Rheumatology to help ensure a diverse and highly trained workforce for those affected with rheumatic diseases.

 

 

UW & Seattle Children's Hospital Joint ForceTake First Place in Jingle Bell Run Fundraising

The UW and Seattle Children's Joint Forces placed first in fundraising amongst all healthcare teams at the 2014 Jingle Bell Run. They had a total of 48 team members representing both institutions - including the Rhuematology Division. The team was made up of faculty, fellows, staff, and friends!

 

Jingle Bell Run 2014

 

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UW Presents 41 Abstracts at ACR Meeting in Boston

The 2014 American College of Rheumatology (ACR) Meeting was held in Boston, Massachusetts from November 15-19. The Division of Rheumatology had a total of 41 abstracts that were presented this year. Our faculty were recognized as the seventh most productive presenters at this national gathering among other Top Ten NIH Institutes.

 

2014 ACR Abstracts

 

Some Abstracts Presented at the 2014 ACR:

 

  • Jie An, Joshua Woodward, Reynold Karr, Thomas Teal, Keith Elkon. The second messenger, Cyclic GMP-AMP dinucleotide (cGAMP) and the enzyme, cyclic GMP-AMP synthase (cGAS), are expressed in Systemic Lupus Erythematosus.
  • Lucrezia Colonna, Christian Lood, YuFeng Peng, Xizhang Sun, Lena Tanaka, Sandip Panicker, Keith B. Elkon. Intracellular Complement C3 Is Exposed on the Cell Surface upon Apoptosis Induction and Participates in the Clearance of Apoptotic Cells By Phagocytes.
  • Tal Gazitt, Jeremy Sokolove. Netosis Induced Histone Citrullination Facilitates Onset and Propagation of Rheumatoid Arthritis.
    • Presented in the first plenary session
  • Natalia Giltiay, Geraldine Shu, Anthony Shock, Edward Clark. Regulation of the Responses of Human B Cell Subsets to Innate Immune Signals By Epratuzumab, a Humanized Monoclonal Antibody Targeting CD22.
  • Jordan Brodsky, Meghan Greenfield, Erin Patton. Osteoporosis Screening and Fracture Risk Assessment Tool Usage Among House Staff.
  • Christian Lood, Xizhang Sun, Lena Tanaka, Jeffrey Ledbetter, Keith Elkon. RNA-containing Immune Complexes shift Human Neutrophils from Phagocytosing Cells to Efficient Releasers of Oxidized DNA in a Process requiring Crosstalk between TLRs and FcgRIIA.
  • Bernard Ng. Factors Associated with Methotrexate Treatment Duration, Including Subcutaneous Use, in Patients with Rheumatoid Arthritis: Observations from the VA Database.
  • Ingeborg Sacksen, Mark Wener, Scott Pollock. Precision of Ultrasound Skin Thickness Measurements: Influence of Examiner and Ultrasound Transducer.
  • Clay Sontheimer, Lucrezia Colonna, Yenly Nguyen, Keith Elkon, YuFeng Peng. Distinct Contributions of C1q and C3 in Preventing Immunogenicity of Apoptotic Cells in Lupus.
  • Clayton Sontheimer, Keith Elkon. Ultraviolet B Generates Type 1 Interferon and Induces Autoantibody-Mediated Disease in a Mouse Model of Cutaneous Lupus.

 

 

New Faculty in Rheumatology

Dr. Natalia Giltiay joined the Division of Rheumatology as Research Assistant Professor September 2014. Dr. Giltiay completed her M.S. in Molecular Biology at Sofia University in Sofia, Bulgaria and Ph.D. in Immunology at the Bulgarian Academy of Sciences. She received her postdoctoral training in the Department of Immunology, Cleveland Clinic Lerner Research Institute. In 2010, she moved to Seattle joining the laboratory of Dr. Edward Clark in the UW Department of Immunology, where she became Acting Instructor. Dr. Giltiay has an extensive background in icellular and molecular mmunology and murine autoimmune models. Her primary research interests are in the field of B lymphocyte biology and B cell regulation with particular emphasis on the signaling mechanisms involved in the survival, differentiation and activation of B cells and how dysregulation of these signals might contribute to the development of systemic autoimmune diseases, such as SLE and SjS.

Dr. Nicole Kieffer is a Georgetown-trained clinical rheumatologist who is joining the rheumatology division at University of Washington. Dr. Kieffer will primarily be seeing patients at the Roosevelt Clinic. Her focus is to provide excellent clinical care for patients with rheumatic disease.

Dr. Amy Tolsdorf attended medical school at the University of Connecticut, where she first discovered her love of Rheumatology. She thereafter moved to Seattle to complete her Internal Medicine Residency and Fellowship in Rheumatology at the University of Washington. During fellowship she also attended school full-time at the UW master’s program in Epidemiology. This year, as a new attending, she looks forward to finishing the master’s program while also having more time for clinical care of patients in the inpatient and outpatient settings.

 

 

Dr. Elkon Awarded LSDF Grant

Dr. Keith Elkon was recently awarded a $250,000 grant from the Life Sciences Discovery Fund (LSDF). LSDF announced nearly $750,000 in Proof of Concept grants to Washington state for-profit and non-profit organizations to promote translation of health-related technologies from the laboratory to the commercial marketplace.

 

Project Title: Targeted Therapy to Inhibit cGAS stimulated Type I IFN Production

Objective: To synthesize and test new drugs for treating systemic lupus erythematosus

 

 

 

Dr. Gordon Starkebaum Appointed as ACR Masters

It gives me great pleasure to announce that Gordon Starkebaum has been appointed as Master of the American College of Rheumatology. As per ACR, the ACR Master “is one of the highest honors the College bestows. The designation of Master is conferred on ACR members, age 65 or older, who have made outstanding contributions to the field of rheumatology through scholarly achievement and/or service to their patients, students, and profession. This honor is usually bestowed upon no more than 20 members per year.”

It is unusual, but Gordon truly has excelled in all four fields of service: clinical care, research, teaching and administration. He joins a distinguished cadre of UW faculty to receive this honor.

Gordon will receive the award at the ACR meeting in Boston. Please join us there and also at a UW dinner to TBA where we can congratulate Gordon.

 

- Keith Elkon, MD, Professor of Medicine and Division Head

 

 

 

Open Rheumatology Job Positions

We have recently posted one new position for a Clinician / Clinician that will primarily be located at Harboview Medical Center. There are other job positions that are still open.

 

Please click here to view the current positions available.