J T BAKER INC Emergency#: 908-859-2151
222 RED SCHOOL LANE Reference#: 800/582-2537
PHILLIPSBURG NEW JERSEY MSDS Rev. Date: 12/20/96
U.S.A. 08865
J.T.BAKER INC. 222 RED SCHOOL LANE, PHILLIPSBURG, NJ 08865
M A T E R I A L S A F E T Y D A T A S H E E T
24-HOUR EMERGENCY TELEPHONE -- (908) 859-2151
CHEMTREC # (800) 424-9300 -- NATIONAL RESPONSE CENTER # (800) 424-8802
D6408 -10 DIMETHYLFORMAMIDE PAGE: 1
EFFECTIVE: 03/03/95 ISSUED: 12/20/96
MALLINCKRODT BAKER,INC., 222 RED SCHOOL LANE, PHILLIPSBURG, NJ 08865
==============================================================================
SECTION I - PRODUCT IDENTIFICATION
==============================================================================
PRODUCT NAME: DIMETHYLFORMAMIDE
COMMON SYNONYMS: N,N-DIMETHYLFORMAMIDE; DMF
CHEMICAL FAMILY: AMIDES
FORMULA: HCON(CH3)2
FORMULA WT.: 73.10
CAS NO.: 68-12-2
NIOSH/RTECS NO.: LQ2100000
PRODUCT USE: LABORATORY REAGENT
PRODUCT CODES: 9344,J766,9222,9223,5233,9221
==============================================================================
PRECAUTIONARY LABELING
==============================================================================
BAKER SAF-T-DATA* SYSTEM
________________________
HEALTH - 3 SEVERE (LIFE)
FLAMMABILITY - 2 MODERATE
REACTIVITY - 1 SLIGHT
CONTACT - 3 SEVERE (LIFE)
LABORATORY PROTECTIVE EQUIPMENT
_______________________________
GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES; CLASS B
EXTINGUISHER
U.S. PRECAUTIONARY LABELING
___________________________
POISON DANGER
COMBUSTIBLE. MAY BE FATAL IF SWALLOWED, INHALED, OR ABSORBED THROUGH SKIN.
EXCEPTIONAL HEALTH AND CONTACT HAZARDS. BEFORE USING, READ MATERIAL SAFETY
DATA SHEET (MSDS) FOR THIS MATERIAL.
KEEP AWAY FROM HEAT, SPARKS, FLAME. DO NOT GET IN EYES, ON SKIN, ON CLOTHING.
DO NOT BREATHE VAPOR. KEEP IN TIGHTLY CLOSED CONTAINER. USE WITH ADEQUATE
VENTILATION. WASH THOROUGHLY AFTER HANDLING. IN CASE OF FIRE, USE WATER
SPRAY, ALCOHOL FOAM, DRY CHEMICAL, OR CARBON DIOXIDE. IN CASE OF SPILL, SOAK
UP WITH SAND OR EARTH. FLUSH SPILL AREA WITH WATER.
CONTINUED ON PAGE: 2
J.T.BAKER INC. 222 RED SCHOOL LANE, PHILLIPSBURG, NJ 08865
M A T E R I A L S A F E T Y D A T A S H E E T
24-HOUR EMERGENCY TELEPHONE -- (908) 859-2151
CHEMTREC # (800) 424-9300 -- NATIONAL RESPONSE CENTER # (800) 424-8802
D6408 -10 DIMETHYLFORMAMIDE PAGE: 2
EFFECTIVE: 03/03/95 ISSUED: 12/20/96
==============================================================================
PRECAUTIONARY LABELING (CONTINUED)
==============================================================================
INTERNATIONAL LABELING
______________________
AVOID CONTACT WITH EYES. AFTER CONTACT WITH SKIN, WASH IMMEDIATELY WITH
PLENTY OF WATER. KEEP CONTAINER TIGHTLY CLOSED.
SAF-T-DATA* STORAGE COLOR CODE: RED (FLAMMABLE)
==============================================================================
SECTION II - COMPONENTS
==============================================================================
COMPONENT CAS NO. WEIGHT % OSHA/PEL ACGIH/TLV
_________ _______ ________ ________ _________
DIMETHYLFORMAMIDE 68-12-2 98-100 10 PPM 10 PPM
==============================================================================
SECTION III - PHYSICAL DATA
==============================================================================
BOILING POINT: 153 C (307 F) VAPOR PRESSURE (MMHG): 2.6
(AT 760 MM HG) (20 C)
MELTING POINT: -61 C (-77 F) VAPOR DENSITY (AIR=1): 2.5
(AT 760 MM HG)
SPECIFIC GRAVITY: 0.95 EVAPORATION RATE: <1
(H2O=1) (BUTYL ACETATE = 1)
SOLUBILITY(H20): COMPLETE (100%) % VOLATILES BY VOLUME: 100
(21 C)
PH: 8.0 (20% SOLUTION)
ODOR THRESHOLD (P.P.M.): N/A PHYSICAL STATE: LIQUID
COEFFICIENT WATER/OIL DISTRIBUTION: N/A
APPEARANCE & ODOR: CLEAR, COLORLESS LIQUID. AMMONIA ODOR.
CONTINUED ON PAGE: 3
J.T.BAKER INC. 222 RED SCHOOL LANE, PHILLIPSBURG, NJ 08865
M A T E R I A L S A F E T Y D A T A S H E E T
24-HOUR EMERGENCY TELEPHONE -- (908) 859-2151
CHEMTREC # (800) 424-9300 -- NATIONAL RESPONSE CENTER # (800) 424-8802
D6408 -10 DIMETHYLFORMAMIDE PAGE: 3
EFFECTIVE: 03/03/95 ISSUED: 12/20/96
==============================================================================
SECTION IV - FIRE AND EXPLOSION HAZARD DATA
==============================================================================
FLASH POINT (CLOSED CUP): 57 C (136 F) NFPA 704M RATING: 1-2-0
AUTOIGNITION TEMPERATURE: 444 C (833 F)
FLAMMABLE LIMITS: UPPER - 15.2 % LOWER - 2.2 %
FIRE EXTINQUISHING MEDIA
________________________
USE WATER SPRAY, ALCOHOL FOAM, DRY CHEMICAL OR CARBON DIOXIDE.
SPECIAL FIRE-FIGHTING PROCEDURES
________________________________
FIREFIGHTERS SHOULD WEAR PROPER PROTECTIVE EQUIPMENT AND SELF-CONTAINED
BREATHING APPARATUS WITH FULL FACEPIECE OPERATED IN POSITIVE PRESSURE
MODE. MOVE CONTAINERS FROM FIRE AREA IF IT CAN BE DONE WITHOUT RISK. USE
WATER TO KEEP FIRE-EXPOSED CONTAINERS COOL.
UNUSUAL FIRE & EXPLOSION HAZARDS
________________________________
VAPORS MAY FLOW ALONG SURFACES TO DISTANT IGNITION SOURCES AND FLASH BACK.
CLOSED CONTAINERS EXPOSED TO HEAT MAY EXPLODE. CONTACT WITH STRONG
OXIDIZERS MAY CAUSE FIRE.
TOXIC GASES PRODUCED
____________________
AMMONIA, OXIDES OF NITROGEN, CARBON MONOXIDE, CARBON DIOXIDE
EXPLOSION DATA-SENSITIVITY TO MECHANICAL IMPACT
_______________________________________________
NONE IDENTIFIED.
EXPLOSION DATA-SENSITIVITY TO STATIC DISCHARGE
______________________________________________
NONE IDENTIFIED.
==============================================================================
SECTION V - HEALTH HAZARD DATA
==============================================================================
THRESHOLD LIMIT VALUE (TLV/TWA): 30 MG/M3 (10 PPM)
THE TLV LISTED DENOTES TLV (SKIN).
SHORT-TERM EXPOSURE LIMIT (STEL): NOT ESTABLISHED
PERMISSIBLE EXPOSURE LIMIT (PEL): 30 MG/M3 (10 PPM)
THE PEL LISTED DENOTES PEL (SKIN).
CONTINUED ON PAGE: 4
J.T.BAKER INC. 222 RED SCHOOL LANE, PHILLIPSBURG, NJ 08865
M A T E R I A L S A F E T Y D A T A S H E E T
24-HOUR EMERGENCY TELEPHONE -- (908) 859-2151
CHEMTREC # (800) 424-9300 -- NATIONAL RESPONSE CENTER # (800) 424-8802
D6408 -10 DIMETHYLFORMAMIDE PAGE: 4
EFFECTIVE: 03/03/95 ISSUED: 12/20/96
==============================================================================
SECTION V - HEALTH HAZARD DATA (CONTINUED)
==============================================================================
TOXICITY OF COMPONENTS
______________________
ORAL RAT LD50 FOR DIMETHYLFORMAMIDE 2800 MG/KG
SKIN RAT LD50 FOR DIMETHYLFORMAMIDE 5000 MG/KG
INTRAPERITONEAL RAT LD50 FOR DIMETHYLFORMAMIDE 1400 MG/KG
INTRAVENOUS RAT LD50 FOR DIMETHYLFORMAMIDE 2000 MG/KG
CARCINOGENICITY: NTP: NO IARC: YES Z LIST: YES OSHA REG: YES
CARCINOGENICITY
_______________
DIMETHYLFORMAMIDE IS POSSIBLY CARCINOGENIC TO HUMANS (GROUP 2B).
REPRODUCTIVE EFFECTS
____________________
TESTS ON LABORATORY ANIMALS INDICATE MATERIAL MAY CAUSE FETAL DEATH.
EFFECTS OF OVEREXPOSURE
______________________
INHALATION: MAY BE FATAL. HEADACHE, NAUSEA, VOMITING, DIZZINESS,
DROWSINESS, IRRITATION OF UPPER RESPIRATORY TRACT,
UNCONSCIOUSNESS
SKIN CONTACT: IRRITATION, PROLONGED CONTACT MAY CAUSE DERMATITIS
EYE CONTACT: IRRITATION
SKIN ABSORPTION: MAY BE FATAL. RAPID ABSORPTION
INGESTION: MAY BE FATAL. HEADACHE, NAUSEA, VOMITING, DIZZINESS,
GASTROINTESTINAL IRRITATION
CHRONIC EFFECTS: DAMAGE TO LIVER, KIDNEYS, BLOOD, CENTRAL NERVOUS SYSTEM
TARGET ORGANS
_____________
LIVER, KIDNEYS, CARDIOVASCULAR SYSTEM, EYES, SKIN, BONE MARROW, CENTRAL
NERVOUS SYSTEM
MEDICAL CONDITIONS GENERALLY AGGRAVATED BY EXPOSURE
___________________________________________________
LIVER DISORDERS
PRIMARY ROUTES OF ENTRY
_______________________
INHALATION, INGESTION, ABSORPTION, EYE CONTACT, SKIN CONTACT
CONTINUED ON PAGE: 5
J.T.BAKER INC. 222 RED SCHOOL LANE, PHILLIPSBURG, NJ 08865
M A T E R I A L S A F E T Y D A T A S H E E T
24-HOUR EMERGENCY TELEPHONE -- (908) 859-2151
CHEMTREC # (800) 424-9300 -- NATIONAL RESPONSE CENTER # (800) 424-8802
D6408 -10 DIMETHYLFORMAMIDE PAGE: 5
EFFECTIVE: 03/03/95 ISSUED: 12/20/96
==============================================================================
SECTION V - HEALTH HAZARD DATA (CONTINUED)
==============================================================================
EMERGENCY AND FIRST AID PROCEDURES
__________________________________
INGESTION: CALL A PHYSICIAN. IF SWALLOWED, IF CONSCIOUS, GIVE LARGE
AMOUNTS OF WATER. INDUCE VOMITING.
INHALATION: IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE
ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE
OXYGEN. PROMPT ACTION IS ESSENTIAL.
SKIN CONTACT: IN CASE OF CONTACT, IMMEDIATELY FLUSH SKIN WITH PLENTY OF
WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED
CLOTHING AND SHOES. WASH CLOTHING BEFORE RE-USE.
EYE CONTACT: IN CASE OF EYE CONTACT, IMMEDIATELY FLUSH WITH PLENTY OF
WATER FOR AT LEAST 15 MINUTES.
SARA/TITLE III HAZARD CATEGORIES AND LISTS
__________________________________________
ACUTE: YES CHRONIC: YES FLAMMABILITY: YES PRESSURE: NO REACTIVITY: NO
EXTREMELY HAZARDOUS SUBSTANCE: NO
CERCLA HAZARDOUS SUBSTANCE: NO
SARA 313 TOXIC CHEMICALS: YES CONTAINS DIMETHYLFORMAMIDE
GENERIC CLASS: GENERIC CLASS REMOVED FROM CFR: 7/1/91
TSCA INVENTORY: YES
==============================================================================
SECTION VI - REACTIVITY DATA
==============================================================================
STABILITY: STABLE HAZARDOUS POLYMERIZATION: WILL NOT OCCUR
CONDITIONS TO AVOID: HEAT, FLAME, OTHER SOURCES OF IGNITION, MOISTURE.
INCOMPATIBLES: STRONG OXIDIZING AGENTS, HALOGENATED HYDROCARBONS,
ACTIVE HALOGEN COMPOUNDS, STRONG ACIDS, STRONG
REDUCING AGENTS, RUBBER, LEATHER, TRIETHYLALUMINUM,
ACID CHLORIDES
DECOMPOSITION PRODUCTS: AMINES, OXIDES OF NITROGEN, CARBON MONOXIDE, CARBON
DIOXIDE
CONTINUED ON PAGE: 6
J.T.BAKER INC. 222 RED SCHOOL LANE, PHILLIPSBURG, NJ 08865
M A T E R I A L S A F E T Y D A T A S H E E T
24-HOUR EMERGENCY TELEPHONE -- (908) 859-2151
CHEMTREC # (800) 424-9300 -- NATIONAL RESPONSE CENTER # (800) 424-8802
D6408 -10 DIMETHYLFORMAMIDE PAGE: 6
EFFECTIVE: 03/03/95 ISSUED: 12/20/96
==============================================================================
SECTION VII - SPILL & DISPOSAL PROCEDURES
==============================================================================
STEPS TO BE TAKEN IN THE EVENT OF A SPILL OR DISCHARGE
______________________________________________________
WEAR SELF-CONTAINED BREATHING APPARATUS AND FULL PROTECTIVE CLOTHING. SHUT
OFF IGNITION SOURCES; NO FLARES, SMOKING OR FLAMES IN AREA. STOP LEAK IF
YOU CAN DO SO WITHOUT RISK. USE WATER SPRAY TO REDUCE VAPORS. TAKE UP
WITH SAND OR OTHER NON-COMBUSTIBLE ABSORBENT MATERIAL AND PLACE INTO
CONTAINER FOR LATER DISPOSAL. FLUSH AREA WITH WATER.
J. T. BAKER SOLUSORB(R) SOLVENT ADSORBENT IS RECOMMENDED FOR SPILLS OF THIS
PRODUCT.
DISPOSAL PROCEDURE
__________________
DISPOSE IN ACCORDANCE WITH ALL APPLICABLE FEDERAL, STATE, AND LOCAL
ENVIRONMENTAL REGULATIONS.
EPA HAZARDOUS WASTE NUMBER: D001 (IGNITABLE WASTE)
==============================================================================
SECTION VIII - INDUSTRIAL PROTECTIVE EQUIPMENT
==============================================================================
VENTILATION: USE GENERAL OR LOCAL EXHAUST VENTILATION TO MEET TLV
REQUIREMENTS.
RESPIRATORY PROTECTION: RESPIRATORY PROTECTION REQUIRED IF AIRBORNE
CONCENTRATION EXCEEDS TLV. AT CONCENTRATIONS ABOVE 10
PPM, A SELF-CONTAINED BREATHING APPARATUS IS ADVISED.
EYE/SKIN PROTECTION: SAFETY GOGGLES AND FACE SHIELD, UNIFORM,PROTECTIVE
SUIT, BUTYL RUBBER GLOVES ARE RECOMMENDED.
==============================================================================
SECTION IX - STORAGE AND HANDLING PRECAUTIONS
==============================================================================
SAF-T-DATA* STORAGE COLOR CODE: RED (FLAMMABLE)
STORAGE REQUIREMENTS
____________________
KEEP CONTAINER TIGHTLY CLOSED. STORE IN A COOL, DRY, WELL-VENTILATED,
FLAMMABLE LIQUID STORAGE AREA OR CABINET. ISOLATE FROM INCOMPATIBLE
MATERIALS.
SPECIAL PRECAUTIONS
___________________
MATERIAL IS HYGROSCOPIC.
CONTINUED ON PAGE: 7
J.T.BAKER INC. 222 RED SCHOOL LANE, PHILLIPSBURG, NJ 08865
M A T E R I A L S A F E T Y D A T A S H E E T
24-HOUR EMERGENCY TELEPHONE -- (908) 859-2151
CHEMTREC # (800) 424-9300 -- NATIONAL RESPONSE CENTER # (800) 424-8802
D6408 -10 DIMETHYLFORMAMIDE PAGE: 7
EFFECTIVE: 03/03/95 ISSUED: 12/20/96
==============================================================================
SECTION X - TRANSPORTATION DATA AND ADDITIONAL INFORMATION
==============================================================================
DOMESTIC (D.O.T.)
_________________
PROPER SHIPPING NAME: N,N-DIMETHYLFORMAMIDE
HAZARD CLASS: 3
UN/NA: UN2265 REPORTABLE QUANTITY: 100 LBS. PACKAGING GROUP: III
LABELS: 3 FLAMMABLE LIQUID
REGULATORY REFERENCES: 49CFR 172.101
INTERNATIONAL (I.M.O.)
______________________
PROPER SHIPPING NAME: N,N-DIMETHYLFORMAMIDE
HAZARD CLASS: 3.3 I.M.O. PAGE: 3335
UN: UN2265 MARINE POLLUTANTS: NO PACKAGING GROUP: III
LABELS: 3 FLAMMABLE LIQUID
REGULATORY REFERENCES: 49CFR PART 176; IMDG CODE
AIR (I.C.A.O.)
______________
PROPER SHIPPING NAME: N,N-DIMETHYLFORMAMIDE
HAZARD CLASS: 3
UN: UN2265 PACKAGING GROUP: III
LABELS: 3 FLAMMABLE LIQUID
REGULATORY REFERENCES: 49CFR PART 175; ICAO=== WE BELIEVE THE TRANSPORTATION
DATA AND REFERENCES CONTAINED HEREIN TO BE FACTUAL AND
THE OPINION OF QUALIFIED EXPERTS. THE DATA IS MEANT AS
A GUIDE TO THE OVERALL CLASSIFICATION OF THE PRODUCT
AND IS NOT PACKAGE SIZE SPECIFIC, NOR SHOULD IT BE
TAKEN AS A WARRANTY OR REPRESENTATION FOR WHICH THE
COMPANY ASSUMES LEGAL RESPONSIBILITY.=== THE
INFORMATION IS OFFERED SOLELY FOR YOUR CONSIDERATION,
INVESTIGATION, AND VERIFICATION. ANY USE OF THE
INFORMATION MUST BE DETERMINED BY THE USER TO BE IN
ACCORDANCE WITH APPLICABLE FEDERAL, STATE, AND LOCAL
LAWS AND REGULATIONS. SEE SHIPPER REQUIREMENTS 49CFR
171.2, CERTIFICATION 172.204, AND EMPLOYEE TRAINING 49
CFR 173.1(B).
U.S. CUSTOMS HARMONIZATION NUMBER: 29241000007
CONTINUED ON PAGE: 8
J.T.BAKER INC. 222 RED SCHOOL LANE, PHILLIPSBURG, NJ 08865
M A T E R I A L S A F E T Y D A T A S H E E T
24-HOUR EMERGENCY TELEPHONE -- (908) 859-2151
CHEMTREC # (800) 424-9300 -- NATIONAL RESPONSE CENTER # (800) 424-8802
D6408 -10 DIMETHYLFORMAMIDE PAGE: 8
EFFECTIVE: 03/03/95 ISSUED: 12/20/96
==============================================================================
NOTE: WHEN HANDLING LIQUID PRODUCTS, SECONDARY PROTECTIVE CONTAINERS MUST BE
USED FOR CARRYING.
-N/A = NOT APPLICABLE, OR NOT AVAILABLE; -N/E = NOT ESTABLISHED
=============================================================================
MALLINCKRODT BAKER PROVIDES THE INFORMATION CONTAINED HEREIN IN GOOD FAITH BUT
MAKES NO REPRESENTATION AS TO ITS COMPREHENSIVENESS OR ACCURACY. THIS
DOCUMENT IS INTENDED ONLY AS A GUIDE TO THE APPROPRIATE PRECAUTIONARY HANDLING
OF THE MATERIAL BY A PROPERLY TRAINED PERSON USING THIS PRODUCT. INDIVIDUALS
RECEIVING THE INFORMATION MUST EXERCISE THEIR INDEPENDENT JUDGMENT
IN DETERMINING ITS APPROPRIATENESS FOR A PARTICULAR PURPOSE.
MALLINCKRODT BAKER MAKES NO REPRESENTATIONS, OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, OR FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT
TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION
REFERS. ACCORDINGLY, MALLINCKRODT BAKER WILL NOT BE RESPONSIBLE FOR
DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
=========================================================================
NOTE: CHEMTREC, CANUTEC AND NATIONAL RESPONSE CENTER EMERGENCY
TELEPHONE NUMBERS ARE TO BE USED ONLY IN THE EVENT OF CHEMICAL EMERGENCIES
INVOLVING A SPILL, LEAK, FIRE, EXPOSURE, OR ACCIDENT INVOLVING
CHEMICALS. ALL NON-EMERGENCY QUESTIONS SHOULD BE DIRECTED TO CUSTOMER
SERVICE (1-800-JTBAKER) FOR ASSISTANCE.
========================================================================
COPYRIGHT 1996 MALLINCKRODT BAKER, INC.
*TRADEMARKS OF MALLINCKRODT BAKER, INC.
APPROVED BY QUALITY ASSURANCE DEPARTMENT.
-- LAST PAGE --
This MSDS is supplied by the Canadian Centre for Occupational Health & Safety.