Armin H. Seidl, Ph.D.


Virginia Merrill Bloedel Hearing Research Center
University of Washington
Box 357923
Seattle, WA 98195

phone: (206) 616-4152
fax: (206) 221-5685
email: armins[a]uw.edu

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Timely delivery of information is essential for proper functioning of the nervous system. Precise regulation of nerve conduction velocity is needed for correct exertion of motor skills, sensory integration and cognitive functions. I use two established model systems, the mammalian auditory brainstem and the avian auditory brainstem, to investigate the development and mechanisms of conduction velocity regulation in axons based on myelin plasticity.



Seidl AH
Regulation of conduction time along axons
Neuroscience. 2013 Jun 29. PubMed

Kashima DT, Rubel EW, Seidl AH.
Pre-target axon sorting in the avian auditory brainstem.
J Comp Neurol. 2012 Dec 14. doi: 10.1002/cne.23287.
[Epub ahead of print] PubMed

Seidl AH, Sanchez JT, Schecterson L, Tabor KM, Wang Y, Kashima DT, Poynter G, Huss D, Fraser SE, Lansford R, Rubel EW.
Transgenic quail as a model for research in the avian nervous system: A comparative study of the auditory brainstem.
J Comp Neurol. 2013 Jan 1;521(1):5-23. doi: 10.1002/cne.23187. PubMed

Sanchez JT, Seidl AH, Rubel EW, Barria A.
Control of neuronal excitability by NMDA-type glutamate receptors in early developing binaural auditory neurons.
J Physiol. 2012 Oct 1;590(Pt 19):4801-18. doi: 10.1113/jphysiol.2012.228734. Epub 2012 Jul 23. PubMed

Korn MJ, Koppel SJ, Li LH, Mehta D, Mehta SB, Seidl AH, Cramer KS.
Astrocyte-secreted factors modulate the developmental distribution of inhibitory synapses in nucleus laminaris of the avian auditory brainstem
J Comp Neurol. 2011 Oct 20. doi: 10.1002/cne.22786. PubMed

Sanchez JT, Seidl AH, Rubel EW, Barria A.
Preparation and culture of chicken auditory brainstem slices
J Vis Exp. 2011 Mar 21;(49). pii: 2527. doi: 10.3791/2527. PubMed

Seidl AH, Rubel EW, Harris DM.
Mechanisms for Adjusting Interaural Time Differences to Achieve Binaural Coincidence Detection
Journal of Neuroscience. 30(1):70 – 80, 2010. PubMed

Seidl AH, Rubel EW.
A simple method for multi-day imaging of slice cultures
Microscopy Res. Technique, 2009 Jun 29. PubMed

Harris JA, Iguchi F, Seidl AH, Lurie DI, Rubel EW.
Afferent deprivation elicits a transcriptional response associated with neuronal survival after a critical period in the mouse cochlear nucleus
J Neurosci. 2008 Oct 22;28(43):10990-1002. PubMed

Siveke I, Pecka M, Seidl AH, Baudoux S, Grothe B.
Binaural Response Properties of Low-Frequency Neurons in the Gerbil Dorsal Nucleus of the Lateral Lemniscus
J Neurophysiol. 2006 Sep;96(3):1425-40. PubMed

Seidl AH, Grothe B.
Development of sound localization mechanisms in the mongolian gerbil is shaped by early acoustic experience.

J Neurophysiol. 2005 Aug;94(2):1028-36. PubMed

Kapfer C, Seidl AH, Schweizer H, Grothe B.
Experience-dependent refinement of inhibitory inputs to auditory coincidence-detector neurons.
Nat Neurosci. 2002 Mar;5(3):247-53. PubMed