PopKinetics, Version 1.0 Features

General

Standard Two-Stage (STS) and Iterated Two-Stage (ITS) parametric population analysis methods
Operates directly on SAAM II single-subject models
Full SAAM II functionality in population setting
Allows population analysis of complex (multi-compartment) models; simple models analyzed quickly and easily
Fast Setup for population analysis (point and click)
- No programming or pseudo code required
- Setup independent of model complexity
- Analysis setup easily modified
Experimental protocol can vary between subjects
Incorporates a Global Tool to rapidly modify model and data attributes for each subject in the population
Requires few assumptions to begin population analyses
User’s notes can be included in Analysis Files to document particular items of interest in an analysis: setup, conclusions, etc.
Includes detailed on-line help with examples

Computations proceeds automatically in populations with constant, fixed, and random effects
Alerts users when there are problems in analyzing data; provides interactive error control; direct integration with SAAM II allows for speedy data and model error identification and correction
Confidence Intervals on population parameters to indicate precision with which population parameters are estimated
Progress Display during analysis

Analysis results may be plotted using General plot or Samples and Data plot is available to examine frequently used results) or listed in Tables; Results may be exported to other applications or printed to a file for additional analysis or reporting - flexible text reporting built in
Provides detailed Logs to examine events that occur during an analysis to allow user to verify that the analysis proceeded as intended