| Director | Yoky Matsuoka | Computer Science & Engineering, UW |
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| Deputy Director | Tom Daniel | Biology, UW |
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| Deputy Director | Kee Moon | Mechanical Engineering, SDSU |
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| Deputy Director | Joel Voldman | Electrical Engineering & Computer Science, MIT |
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| Industry & Innovation Director | Bob Wilcox | |
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| Industry & Innovation co-Director | Kristina Hudson | Enterprise Seattle |
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| Educational Director | Eric Chudler | Bioengineering, UW |
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| Educational Director | William Moody | Biology, UW |
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| Pre-College Educational Director | James Dorsey | Math Engineering & Science Achievement, UW |
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| Thrust Leaders | Howard Chizeck | Electrical Engineering, UW |
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| | Sam Kassegne | Mechanical Engineering, SDSU |
| | Kristi Morgansen | Aeronautics & Astronautics, UW |
| | Brian Otis | Electrical Engineering, UW |
| | Rajesh Rao | Computer Science & Engineering, UW |
| | Fred Rieke | Physiology & Biophysics, uw |
| | Joan Sanders | Bioengineering, UW |
| | Joel Voldman | Electrical Engineering & Computer Science, MIT |