Taylor ND, Garruss AS, Moretti R, Chan S, Arbing MA, Cascio D, Rogers JK, Isaacs FJ, Kosuri S, Baker D, Fields S, Church GM, Raman S. Engineering an allosteric transcription factor to respond to new ligands. Mol Biol Cell. 2015 Nov 5;26(22):3904-8. download pdf

Shendure J, Fields S. Massively Parallel Genetics. 2016 Jun;203(2):617-9. download pdf

Feng J, Jester BW, Tinberg CE, Mandell DJ, Antunes MS, Chari R, Morey KJ, Rios X, Medford JI, Church GM, Fields S, Baker D. A general strategy to construct small molecule biosensors in eukaryotes. Elife. 2015 Dec 29;4. pii: e10606. doi: 10.7554/eLife.10606. download pdf

Young DL, Fields S. The role of functional data in interpreting the effects of genetic variation. Mol Biol Cell. 2015 Nov 5;26(22):3904-8. download pdf

Starita LM, Young DL, Islam M, Kitzman JO, Gullingsrud J, Hause RJ, Fowler DM, Parvin JD, Shendure J, Fields S. Massively Parallel Functional Analysis of BRCA1 RING Domain Variants. Genetics. 2015 Mar 30. download pdf

Cuperus JT, Lo RS, Shumaker L, Proctor J, Fields S. A tetO Toolkit To Alter Expression of Genes in Saccharomyces cerevisiae. ACS Synth Biol. 2015 Mar 17. download pdf

Melamed D, Young DL, Miller CR, Fields S. Combining natural sequence variation with high throughput mutational data to reveal protein interaction sites. PLoS Genet. 2015 Feb 11;11(2):e1004918. download pdf

Vidal M, Fields S. The yeast two-hybrid assay: still finding connections after 25 years. Nat Methods. 2014 Dec;11(12):1203-6. download pdf

Kitzman JO, Starita LM, Lo RS, Fields S, Shendure J. Massively parallel single-amino-acid mutagenesis. Nat Methods. 2015 Mar;12(3):203-6. download pdf

Raman S, Taylor N, Genuth N, Fields S, Church GM. Engineering allostery. Trends Genet. 2014 Dec;30(12):521-8. download pdf

Fowler DM, Stephany JJ, Fields S. Measuring the activity of protein variants on a large scale using deep mutational scanning. Nature Protocols. 2014 Sep;9(9):2267-84.

Fowler DM, Fields S. Deep mutational scanning: a new style of protein science. Nature Methods. 2014 Aug;11(8):801-7.

Bennett CL, Chen Y, Vignali M, Lo RS, Mason AG, Unal A, Huq Saifee NP, Fields S, La Spada AR. Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide. PLoS One. 2013 Nov 11;8(11). download pdf

Melamed D, Young DL, Gamble CE, Miller CR, Fields S. Deep mutational scanning of an RRM domain of the Saccharomyces cerevisiae poly(A)-binding protein. RNA. 2013 Nov;19(11):1537-51. Epub 2013 Sep 24. download pdf

Kim I, Miller CR, Young DL, Fields S. High-throughput Analysis of in vivo Protein Stability. Mol Cell Proteomics. 2013 Jul 29. [Epub ahead of print]. download pdf

Skelly DA, Merrihew GE, Riffle M, Connelly CF, Kerr EO, Johansson M, Jaschob D, Graczyk B, Shulman NJ, Wakefield J, Cooper SJ, Fields S, Noble WS, Muller EG, Davis TN, Dunham MJ, Maccoss MJ, Akey JM. Integrative phenomics reveals insight into the structure of phenotypic diversity in budding yeast. Genome Res. 2013 Sep;23(9):1496-504. doi: 10.1101/gr.155762.113. Epub 2013 May 29. download pdf

Gold MG, Fowler DM, Means CK, Pawson CT, Stephany JJ, Langeberg LK, Fields S, Scott JD. Engineering A-kinase anchoring protein (AKAP)-selective regulatory subunits of protein kinase A (PKA) through structure-based phage selection. J Biol Chem. 2013 Jun 14;288(24):17111-21. download pdf

Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods. 2013 Jul;10(7):676-82. doi: 10.1038/nmeth.2519. Epub 2013 Jun 9. download pdf

Starita LM, Pruneda JN, Lo RS, Fowler DM, Kim HJ, Hiatt JB, Shendure J, Brzovic PS, Fields S, Klevit RE. Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis. Proc Natl Acad Sci U S A. 2013 Mar 18. download pdf

Araya CL, Fowler DM, Chen W, Muniez I, Kelly JW, Fields S. A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function. Proc Natl Acad Sci. 2012 Oct 16;109(42):16858-63. download pdf

Duan Z, Andronescu M, Schutz K, Lee C, Shendure J, Fields S, Noble WS, Anthony Blau C. A genome-wide 3C-method for characterizing the three-dimensional architectures of genomes. Methods. 2012 Jul 6. download pdf

McGarvey KM, Queitsch K, and Fields S. Wide variation in antibiotic resistance proteins identified by functional metagenomic screening of a soil DNA library. Applied and Environmental Microbiology. 2012 Mar;78(6):1708-14. Epub 2012 Jan 13. download pdf

McKinlay A, Gerard W, Fields S. Global analysis of RNA oxidation in Saccharomyces cerevisiae. Biotechniques. 2012 Feb;52(2):109-11. download pdf

Starita, L.M., Lo, R.S., Eng, J.K., Von Haller, P.D. and Fields, S. Sites of ubiquitin attachment in Saccharomyces cerevisiae.  Proteomics. 2012 Jan;12(2):236-240. Epub 2011 Nov 22 download pdf

McKinlay, A., Araya, C.L. and Fields, S. Genome-wide analysis of nascent transcription in Saccharomyces cerevisiae. G3: Genes, Genomes, Genetics. 2011 Dec;1(7):549-58. Epub 2011 Dec 1. download pdf
Lo, M., Brett, C.L., Plemel, R., Vignali, M., Fields, S., Gonen, T., and Merz, A.J. Intrinsic tethering activity of endosomal Rab proteins. Nature Structural and Molecular Biology. 2011 Dec 11;19(1):40-7. download pdf

Fowler DM, Araya CL, Gerard W, Fields S. Enrich: Software for Analysis of Protein Function by Enrichment and Depletion of Variants. Bioinformatics. Bioinformatics. 2011 Dec 15;27(24):3430-1. Epub 2011 Oct 17. download pdf

Araya CL, Fowler DM. Deep mutational scanning: assessing protein function on a massive scale. Trends in Biotechnology. 2011 Sep;29(9):435-42. Epub 2011 May 10. download pdf

Brown HF, Wang L, Khadka S, Fields S, LaCount DJ. A densely overlapping gene fragmentation approach improves yeast two-hybrid screens for Plasmodium falciparum proteins. Mol Biochem Parasitol. 2011 Jul-Aug;178(1-2):56-9. Epub 2011 Apr 20. download pdf

Ren L, McLean JR, Hazbun TR, Fields S, Vander Kooi C, Ohi MD, Gould KL. Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19. PLoS One. 2011 Feb 28;6(2):e16719. download pdf

Fowler DM, Cooper SJ, Stephany JJ, Hendon N, Nelson S and Fields S. Suppression of statin effectiveness by copper and zinc in yeast and human cells. Mol. BioSyst. 2011, Feb;7(2):533-544. download pdf

Piña FJ, O'Donnell AF, Pagant S, Piao HL, Miller JP, Fields S, Miller EA, Cyert MS. Hph1 and Hph2 are novel components of the Sec63/Sec62 posttranslational translocation complex that aid in vacuolar proton ATPase biogenesis. Eukaryot Cell. 2011 Jan;10(1):63-71. download pdf

Fowler DM, Araya CL, Fleishman SJ, Kellogg EH, Stephany JJ, Baker D, Fields S. High-resolution mapping of protein sequence-function relationships. Nat Methods. 2010 Sep;7(9):741-6. download pdf

Cooper SJ, Finney GL, Brown SL, Nelson SK, Hesselberth J, Maccoss MJ, Fields S. High-throughput profiling of amino acids in strains of the Saccharomyces cerevisiae deletion collection. Genome Res. 2010 Sep;20(9):1288-96. download pdf

Duan Z, Andronescu M, Schutz K, McIlwain S, Kim YJ, Lee C, Shendure J, Fields S, Blau CA, Noble WS. A three-dimensional model of the yeast genome. Nature. 2010 May 20;465(7296):363-7. download pdf

Araya CL, Payen C, Dunham MJ, Fields S. Whole-genome sequencing of a laboratory-evolved yeast strain. BMC Genomics. 2010 Feb 3;11:88. download pdf

Schutz K, Hesselberth JR, Fields S. Capture and sequence analysis of RNAs with terminal 2',3'-cyclic phosphates. RNA. 2010 Mar;16(3):621-31. download pdf, supplemental figures, supplemental figure legends, supplemental raw seq data

Fields S. Interactive learning: lessons from two hybrids over two decades. Proteomics. 2009 Dec;9(23):5209-13. download pdf

Hesselberth JR, Chen X, Zhang Z, Sabo PJ, Sandstrom R, Reynolds AP, Thurman RE, Neph S, Kuehn MS, Noble WS, Fields S, Stamatoyannopoulos JA. Global mapping of protein-DNA interactions in vivo by digital genomic footprinting. Nat Methods. 2009 Apr;6(4):283-9. download pdf

Lacount DJ, Schoenfeld LW, Fields S. Selection of yeast strains with enhanced expression of Plasmodium falciparum proteins.
Mol Biochem Parasitol. 2009 Feb;163(2):119-22. download pdf

Vignali M, McKinlay A, LaCount DJ, Chettier R, Bell R, Sahasrabudhe S, Hughes RE, Fields S. Interaction of an atypical Plasmodium falciparum ETRAMP with human apolipoproteins. Malar J. 2008 Oct 20;7:211. download pdf, supplemental data

Brett CL, Plemel RL, Lobinger BT, Vignali M, Fields S, Merz AJ. Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase. J Cell Biol. 2008 Sep 22;182(6):1141-51. download pdf, supplemental data

Khoury CM, Yang Z, Li XY, Vignali M, Fields S, Greenwood MT. A TSC22-like motif defines a novel antiapoptotic protein family. FEMS Yeast Res. 2008 Jun;8(4):540-63. download pdf

Steffen KK, MacKay VL, Kerr EO, Tsuchiya M, Hu D, Fox LA, Dang N, Johnston ED, Oakes JA, Tchao BN, Pak DN, Fields S, Kennedy BK, Kaeberlein M. Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4. Cell. 2008 Apr 18;133(2):292-302. download pdf, supplemental data

Wong J, Nakajima Y, Westermann S, Shang C, Kang JS, Goodner C, Houshmand P, Fields S, Chan CS, Drubin D, Barnes G, Hazbun T. A protein interaction map of the mitotic spindle. Mol Biol Cell. 2007 Oct;18(10):3800-9. download pdf, supplemental data

Fields S. Molecular biology. Site-seeing by sequencing. Science. 2007 Jun 8;316(5830):1441-2. download pdf

Gerstein M, Seringhaus M, Fields S. Structured digital abstract makes text mining easy. Nature. 2007 May 10;447(7141):142. download pdf

Zhang Z, Hesselberth JR, Fields S. Genome-wide identification of spliced introns using a tiling microarray.
Genome Res. 2007 Mar 9. download pdf, supplemental data

Kaeberlein TL, Smith ED, Tsuchiya M, Welton KL, Thomas JH, Fields S, Kennedy BK, Kaeberlein M. Lifespan extension in Caenorhabditis elegans by complete removal of food. Aging Cell. 2006 Dec;5(6):487-94. download pdf

Fields S, Nickerson DA, Waterston RH, Ramsey PG. Positioning a medical school for modern biomedical research: the department of genome sciences at the University of Washington School of Medicine. Acad Med. 2006 Oct;81(10):882-5. download pdf

Montpetit B, Hazbun TR, Fields S, Hieter P. Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation. J Cell Biol. 2006 Aug 28;174(5):653-63. download pdf

Kaeberlein M, Steffen KK, Hu D, Dang N, Kerr EO, Tsuchiya M, Fields S, Kennedy BK. Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Science. 2006 Jun 2;312(5778):1312. download pdf

Hesselberth JR, Miller JP, Golob A, Stajich JE, Michaud GA, Fields S. Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins. Genome Biol. 2006 Apr 10;7(4):R30. download pdf

Jin F, Hazbun T, Michaud GA, Salcius M, Predki PF, Fields S, Huang J. A pooling-deconvolution strategy for biological network elucidation. Nature Methods. 2006 Mar;3(3):183-9. download pdf

Brown V, Brown RA, Ozinsky A, Hesselberth JR, Fields S. Binding specificity of Toll-like receptor cytoplasmic domains. Eur J Immunol. 2006 Mar;36(3):742-53. download pdf

Powers RW 3rd, Kaeberlein M, Caldwell SD, Kennedy BK, Fields S. Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev. 2006 Jan 15;20(2):174-84. download pdf

Kaeberlein M, Hu D, Kerr EO, Tsuchiya M, Westman EA, Dang N, Fields S, Kennedy BK. Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast. PLoS Genet. 2005 Nov 25;1(5):e69. download pdf

Kaeberlein M, Powers RW 3rd, Steffen KK, Westman EA, Hu D, Dang N, Kerr EO, Kirkland KT, Fields S, Kennedy BK. Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science. 2005 Nov 18;310(5751):1193-6. download pdf

Lacount DJ, Vignali M, Chettier R, Phansalkar A, Bell R, Hesselberth JR, Schoenfeld LW, Ota I, Sahasrabudhe S, Kurschner C, Fields S, Hughes RE. A protein interaction network of the malaria parasite Plasmodium falciparum. Nature. 2005 Nov 3;438(7064):103-7. download pdf

Fields S. (2005) High-throughput two-hybrid analysis. The promise and the peril. FEBS J. Nov;272(21):5391-9. download pdf

Miller J.P., Lo R.S., Ben-Hur A, Desmarais C, Stagljar I, Stafford Noble W, Fields S.(2005) Large-scale identification of yeast integral membrane protein interactions. Proc Natl Acad Sci USA. Aug 23;102(34):12123-12128. supplemental data, download pdf

Natter K, Leitner P, Faschinger A, Wolinski H, McCraith S, Fields S, Kohlwein SD. (2005) The Spatial Organization of Lipid Synthesis in the Yeast Saccharomyces cerevisiae Derived from Large Scale Green Fluorescent Protein Tagging and High Resolution Microscopy. Mol Cell Proteomics. May;4(5):662-672. download pdf

Devit M, Cullen PJ, Branson M, Sprague GF Jr, Fields S. (2005) Forcing interactions as a genetic screen to identify proteins that exert a defined activity. Genome Res. Apr;15(4):560-5. download pdf

Fields S, Johnston M. (2005) Cell biology. Whither model organism research? Science. Mar 25;307(5717):1885-6. download pdf

Kaeberlein M, Kirkland KT, Fields S, Kennedy BK. (2005) Genes determining yeast replicative life span in a long-lived genetic background. Mech Ageing Dev. Apr;126(4):491-504. download pdf

Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell S, Napper A, Curtis R, Distefano PS, Fields S, Bedalov A, Kennedy BK. (2005) Substrate specific activation fo sirtuins by resveratrol.
J Biol Chem. Apr 29;280(17):17038-45. download pdf

Jeffress M, Fields S. (2005) Identification of putative Plasmodium falciparum mefloquine resistance genes. Mol Biochem Parasitol. Feb;139(2):133-9. download pdf

Antoniacci LM, Kenna MA, Uetz P, Fields S, Skibbens RV. (2004) The spindle pole body assembly component mps3p/nep98p functions in sister chromatid cohesion. J Biol Chem. Nov 19;279(47):49542-50. download pdf

Kaeberlein, M., Kirkland, K.T., Fields, S. and Kennedy, B.K. (2004) Sir2-independent life span extension by calorie restriction in yeast. PLoS Biology Sep;2(9):E296. download pdf

Alexandrov, A., Vignali, M., LaCount, D.J., Quartley, E., de Vries, C., DeRosa, D., Babulski, J., Mitchell, S., Schoenfeld, L.W., Fields, S., Hol, W.G., Dumont, M.E., Phizicky, E.M. and Grayhack,E.J. (2004) A facile method for high-throughput co-expression of protein pairs. Molecular and Cellular proteomics Sep;3(9):934-938. download pdf

Guo, D., Hazbun, T.R., Xu, X.-J., Ng, S.-L., Fields, S. and Kuo, M.-H. (2004) A tethered catalysis two-hybrid system to identify protein-protein interactions requiring post-translational modifications. Nature Biotechnology Jul;22(7):888-892. download pdf

Tucker, C.L. and Fields, S. (2004) Quantitative genome-wide analysis of yeast deletion strain sensitivities to oxidative and chemical stress. Comparative and Functional Genomics 5:216-224. supplemental data, download pdf

Hazbun, T.R., Malmström, L., Anderson, S., Graczyk, B.J., Fox, B., Riffle, M., Sundin, B.A., Aranda, J.D., McDonald, W.H., Chun, C., Snydsman, B.E., Bradley, P., Muller, E.G.D., Fields, S., Baker, D., Yates, J.R. III and Davis, T.N. (2003) Assigning function to yeast proteins by integration of technologies. Molecular Cell Dec;12(6):1353-1365. download pdf

Tucker CL, Fields S. (2003) Lethal combinations. Nat Genet. 2003 Nov;35(3):204-5. download pdf

Guo, M., Uetz, P., Burchett, S.A., Fields, S. and Dohlman, H.G. (2003) The yeast G protein alpha subunit Gpa1 transmits a signal through a novel effector RNA-binding protein Scp160. Mol. Cell, Aug;12(2):517-524. download pdf

Shang, C., Hazbun, T.R., Cheeseman, I.M., Aranda, J., Fields, S., Drubin, D.G. and Barnes, G. (2003) Kinetochore protein interactions and their regulation by the Aurora kinase Ipl1p. Molecular Biology of the Cell Aug;14(8):3342-55. download pdf

Kitagawa, K., Abdulle, R., Bansal, P.K., Cagney, G., Fields, S. and Hieter, P. (2003) Requirement of Skp1-Bub1 interaction for kinetochore-mediated activation of the spindle checkpoint. Molecular Cell May;11(5):1201-1213. download pdf

Phizicky, E., Bastiaens, P. I. H., Zhu, H., Snyder, M. and Fields, S. (2003) Protein analysis on a proteomic scale. Nature Mar;422(6928):208-215. download pdf

Pot, I., Measday, V., Snydsman, B., Cagney, G., Fields, S., Muller, E., Davis, T.N. and Hieter, P. (2002) Chl4p and Iml3p are two new members of the budding yeast outer kinetochore. Mol. Biol. Cell Feb;14(2):460-76. download pdf

Stagljar, I. and Fields, S. (2002) Analysis of membrane protein interactions using yeast-based technologies. Trends in Biochemical Sciences Nov;27(11): 559-563. download pdf

Fields, S. (2002) Forward to Discovering Genomics, Proteomics and Bioinformatics, A.M. Campbell and L.J. Heyer (San Francisco: Benjamin Cummings), p. ix.

Hazbun, T. R. and Fields, S. (2002) A genome-wide screen for site-specific DNA binding proteins. Mol. Cell Proteomics Jul;1(7):538-43. download pdf

Phizicky, E.M., Martzen, M.R., McCraith, S. M., Spinelli, S.L., Xing, F., Shull, N.P., Van Slyke, C., Montagne, R.K., Torres, F.M., Fields, S. and Grayhack, E.J. (2002) Biochemical genomics approach to map activities to genes. Methods Enzymol 350:546-59.

von Mering, C., Krause, R., Snel, B., Cornell, M., Oliver, S.G., Fields, S. and Bork, P. (2002) Comparative assessment of large-scale data sets of protein-protein interactions. Nature May 23;417(6887):399-403. download pdf

Fields, S. and Johnston, M. (2002) Genomics. A crisis in postgenomic nomenclature. Science Apr 26;296(5568): 671-672. download pdf

Burchett, S.A., Flanary, P., Aston, C.W., Jiang, L., Young, K.H., Uetz, P., Fields, S. and Dohlman, H.G. (2002) Regulation of stress response signaling by the N-terminal DEP (dishevelled/EGL-10/pleckstrin) domain of Sst2, a regulator of G protein signaling in Saccharomyces cerevisiae. J. Biol. Chem. Jun 21;277(25):22156-67. download pdf

Measday, V., Hailey D., Pot, I., Givan, S., Hyland, K., Cagney, G., Fields, S., Davis, T. and Hieter, P. (2002) Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore . Genes and Development Jan 1;16(1):101-113. download pdf

Muchowski, P., Ning, K., D’Souza-Schorey and Fields, S. (2002) Requirement of an intact microtubule cytoskeleton for the aggregation of an amino-terminal fragment of huntingtin. Proc Natl Acad Sci USA. Jan 22;99(2): 727-732. download pdf

Gera, J.F., Hazbun, T.R. and Fields, S. (2002) Array-based methods for identifying protein-protein and protein-nucleic acid interactions. Methods Enzymol. 350:499-512.

Tong, A. H., Drees, B., Nardelli, G., Bader, G. D., Brannetti, B., Castagnoli, L., Evangelista, M., Ferracuti, S., Nelson, B., Paoluzi, S., Quondam, M., Zucconi, A., Hogue, C. W., Fields, S., Boone, C., and Cesareni, G. (2001) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science Jan 11;295(5553):284-7. download pdf

Hughes, R. E., Lo, R. S., Davis, C., Strand, A. D., Neal, C. L., Olson, J. M. and Fields, S. (2001) Altered transcription in yeast expressing polyglutamine. Proc. Natl. Acad. Sci. USA. Nov 6;98(23):13201-06. download pdf

Cagney, G., Uetz, P. and Fields, S. (2001) Two-hybrid analysis of the Saccharomyces cerevisiae 26S proteasome. Physiol. Genomics Oct 10;7(1):27-34. download pdf

Tucker, C. and Fields, S. (2001) A yeast sensor of ligand binding. Nat. Biotech. Nov;19(11):1042-1046. download pdf

Fields, S. (2001) The interplay of biology and technology. Proc. Natl. Acad. Sci. U.S.A. Aug 28;98(18):10051-10054. download pdf

Drees,B.L., Sundin, B., Brazeau, E., Caviston, J.P., Chen, G.-C., Guo, W., Kozminski, K.G., Lau, M.W., Moskow, J.J., Tong, A., Schenkman, L.R., McKenzie, A. III, Brennwald, P., Longtine, M., Bi, E., Chan, C., Novick, P., Boone, C., Pringle, J.R., Davis, T.N., Fields, S. and Drubin, D.G. (2001) A protein interaction map for cell polarity development. J. Cell Biol. Aug 6;154(3):549-571. download pdf

Fields, S. (2001) Proteomics in genomeland. Science Feb 16;291(5507):1221-1224. download pdf

Wood, J., Frederickson, R.M., Fields, S. and Patel, A.H. (2001) Hepatitis C virus 3' X region interacts with human ribosomal proteins. J. Virol. Feb;75(3):1348-1358. download pdf

Johnston, M. and Fields, S., eds. (2001) Proteomics and genomics. Presidential preference, protein purpose. Curr. Opin. Chem. Biol., 5(1):13-14.

Fields, S. (2001) Two hybrid proteins to many hybrid proteins. ASM News 67:135-143.

Hazbun, T.R. and Fields, S. (2001) Networking proteins in yeast. Proc. Natl. Acad. Sci. U.S.A. Apr 10;98(8):4277-4278. download pdf

Kraemer, B., Zhang, B., SenGupta, S., Fields, S. and Wickens, M. (2000) Using the yeast three-hybrid system to detect and analyze RNA-protein interactions. Meth. Enzym. 328:297-321.

Cagney, G., Uetz, P. and Fields, S. (2000) High-throughput screening for protein-protein interactions using two-hybrid assay. Meth. Enzym. 328:3-14.

Zhang B, Kraemer B, SenGupta D, Fields S, and Wickens M. (2000) Yeast three-hybrid system to detect and analyze RNA-protein interactions. Meth. Enzym. 318:399-419.

McCraith, S., Holtzman, T., Moss, B. and Fields, S. (2000) Genomewide analysis of vaccinia virus protein-protein interactions. Proc. Natl. Acad. Sci. U.S.A Apr 25;97(9): 4879-4884. download pdf

Crosby , J.A., Konopka, J.B. and Fields, S. (2000) Constitutive activation of the Saccharomyces cerevisiae transcriptional regulator Ste12p by mutations at the amino-terminus. Yeast Nov;16(15):1365-1375. download pdf

Schwikowski, B., Uetz, P. and Fields, S. (2000) A network of protein-protein interactions in yeast. Nature Biotech. Dec;18(12):1257-1261. download pdf

Uetz, P. Giot, L. Cagney, G. Mansfield, T. A., Judson, R. S., Narayan, V. Lockshon, D., Srinivasan, M., Pochart, P., Qureshi-Emili, A., Li, Y., Godwin, B., Conover, D., Kalbfleisch, T., Vijayadamodar, G., Yang, M., Johnston, M., Fields, S. and Rothberg, J. M. (2000) A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae. Nature Feb 10;403(6770):623-7. download pdf

Johnson, M. and Fields, S. (2000) Grass roots genomics.  Nature Genet. Jan;24(1):5-6.

Drees, B. L. (1999) Progress and variations in two-hybrid and three-hybrid technologies. Curr. Opin. Chem. Biol. Feb;3(1):64-70. download pdf

Martzen, M. R., McCraith, S. M., Spinelli, S. L., Torres, F. M., Fields, S., Grayhack, E. J. and Phizicky, E. M. (1999) A biochemical genomics approach for identifying genes by the activity of their products. Science Nov 5;286(5442):1153-55. download pdf

Norman, T. C., Smith, D. L., Sorger, P. K., Drees, B. L., O'Rourke, S. M., Hughes, T. R., Roberts, C. J., Friend, S. H., Fields, S. and Murray, A. W. (1999) Genetic selection of peptide inhibitors of biological pathways. Science Jul 23;285(5427):591-5. download pdf

Fields, S., Kohara, Y. and Lockhart, D. J. (1999) Functional genomics. (Frontiers of Science Symposium review) Proc. Natl. Acad. Sci. Aug 3;96(16):8825-26. download pdf

Fields, S. (1999) Two-hybrid and related systems.  In Encyclopedia of Life Sciences.  London: Macmillan.

Zhang, B., Kraemer, B., SenGupta, S., Fields, S. and Wickens, M. (1999) Yeast three-hybrid system to detect and analyze interactions between RNA and protein. Meth.Enzym. 306:93-113.

Wright, M. E., Han, D. K., Carter, L., Fields, S., Schwartz, S. M., and Hockenbery, D. M. (1999) Caspase-3 inhibits growth in Saccharomyces cerevisiae without causing cell death. FEBS Lett. Mar 5;446(1):9-14. download pdf

Hughes, R. E. and Fields, S. (1999) The PDZ domain as you like it. Nat. Biotechnol. Feb;17(2):132-3.

SenGupta, D. J., Wickens, M. and Fields, S. (1999) Identification of RNAs that bind to a specific protein using the yeast three-hybrid system. RNA Apr;5(4):596-601. download pdf

Department of

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Univ. of Washington

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