Clement E. Furlong
Research Professor
Departments of Medicine (Div. Medical Genetics) & Genome Sciences

Contact

E-mail: clem@u.washington.edu
Website: http://www.gs.washington.edu/faculty/furlong.htm

Research interests

1) Gene-environment interactions
2) development of SPR-based biosensors for real-time detection of analytes (toxicants/toxins & other small molecules, proteins/toxic proteins, viruses, microbes)
3) production of therapeutic human proteins in E. coli bioreactor systems
4) identification of biomarkers of exposure to OP compounds

Recent publications, posters & presentations

JN Hofmann, MC Keifer, H Checkoway, AJ De Roos, FM Farin, RA Fenske, RJ Richter, G van Belle, CE Furlong. 2009. Biomarkers of sensitivity and exposure in Washington State pesticide handlers. Proceedings of the 3rd International Conference on Paraoxonases. (In Press)

JN Hofmann, MC Keifer, AJ De Roos, FM Farin, RA Fenske, CE Furlong, G van Belle, H Checkoway. Serum cholinesterase inhibition in relation to paraoxonase 1 status among organophosophate-exposed agricultural pesticide handlers. Poster. Superfund Basic Research Program Annual Meeting, Pacific Grove, CA, December 7-9, 2008.

JN Hofmann, MC Keifer, AJ De Roos, FM Farin, RA Fenske, CE Furlong, G van Belle, H Checkoway. Serum cholinesterase inhibition in relation to paraoxonase 1 status among organophosophate-exposed agricultural pesticide handlers. Poster. New Paths: Health and Safety in Western Agriculture: Cle Elum, WA. November 2008.

JN Hofmann, MC Keifer, AJ De Roos, FM Farin, RA Fenske, CE Furlong, G van Belle, H Checkoway. Serum cholinesterase inhibition in relation to paraoxonase 1 status among organophosophate-exposed agricultural pesticide handlers. Poster. 2008 Annual NIEHS P30 Director's Meeting: Philadelphia, PA. October 2008.

JN Hofmann, JH Kim, R Stevens, M MacCoss, D Goodlett, AC Sherl, MC Keifer, H Checkoway, RJ Richter, SM Suzuki, FM Farin, AJ De Roos, CE Furlong. Biomarkers of sensitivity and exposure in Washington State Pesticide Handlers. 3rd International Conference on Paraoxonases: Los Angeles, CA. Oral and poster. September 10, 2008

JN Hofmann, AJ De Roos, CE Furlong, FM Farin, RA Fenske, H Checkoway, MC Keifer. Serum cholinesterase inhibition in relation to paraoxonase 1 status among organophosphate-exposed agricultural pesticide workers. Presented at the International Conference on Epidemiology in Occupational Health, San Jose, Costa Rica, June 2008.

Furlong CE, Cole TB, Walter BJ, Shih DM, Tward A, Lusis AJ, Timchalk C, Richter RJ, Costa LG. 2005. Paraoxonase 1 (PON1) status and risk of insecticide exposure. J Biochem Mol Toxicol. 19:182-3.

Furlong CE, Cole TB, Jarvik GP, Pettan-Brewer C, Geiss GK, Richter RJ, Shih DM, Tward AJ, Lusis AJ, Costa LG. 2005. Role of paraoxonase (PON1) Status in pesticide sensitivity: genetic and temporal determinants. Neurotoxicology 26:651-659.

Furlong C, Holland N, Richter R, Bradman A, Ho A, and B Eskenazi. 2006. PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. Pharmacogenetics and Genomics. 16:183-190.