Dr. Evan P. Gallagher, Ph.D.
Sheldon D. Murphy Professor of Environmental Health Sciences
Director,
Toxicology Program
Contact
Phone: (206) 616-4739
Fax: (206) 685-4696
Laboratory phone: (206) 543-1005
Laboratory Contact: Mike Espinoza
Email: evang3@u.washington.edu
Website: http://depts.washington.edu/envhlth/faculty.php?Gallagher_Evan
Research Interests
Dr. Gallagher maintains an active research program focused in the area of the molecular and biochemical basis for susceptibility of environmental chemical toxicity. Specifically, our work is directed toward an understanding of the role of genetics and biochemistry of oxidative defense and biotransformation enzyme expression in individual, developmental, and species’ differences in susceptibility to environmental chemicals. Our work encompasses studies in Pacific salmon and zebrafish, as well as in fish and human cell models. Accordingly, we address toxicological issues that often involve ecological and human health.
Recent Publications
Trute,
M., Gallus, B., Goodlett, D. and GALLAGHER, E.P. 2007. Glutathione
S-transferase isozyme expression in coho salmon liver. Aquatic
Toxicology. 81:126-136
Shao,
J., Janssen, P. Lin, Y. and GALLAGHER, E.P. 2007. Cytochrome P450
and glutathione S- transferase system isoform mRNA expression
in human fetal liver hematopoietic stem cells. Drug
Metabolism and Disposition. 35:168-175.
Steiner,
C., Peters, W.H.M., GALLAGHER, E.P. and B L. Pool-Zobel. 2007.
Genistein protects human mammary epithelial cells from genotoxicity
by modulating the glutathione/glutathione S-transferase system.
Carcinogenesis. 28:738-748.
GALLAGHER,
E.P., Gardner, J.S. and D.L. Barber. 2006. Several glutathione
S-transferase isozymes that protect against oxidative injury are
expressed in human liver mitochondria. Biochem.
Pharmacol. 71(11) 1619-1628.
Moneypenny,
C.G, Shao, J., Song Y., and E.P. GALLAGHER. 2006. Etoposide-induced
DNA damage and MLL gene rearrangements in cultured human fetal
liver hematopoietic stem cells. Carcinogenesis.
27(4)871-881.
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