The Superfund Research Program is an interdisciplinary team of faculty
and graduate students from the University Of Washington departments of
Environmental and Occupational Health Sciences, Epidemiology, Genome Sciences, Biostatistics, Civil Engineering, Biochemistry, Forestry and Microbiology.
- Develop biological markers to assess exposure to
nervous system toxicants and susceptibility to disease
- Assess physiological damage in humans and wildlife
- Develop new technology to remediate contaminated
Biomarkers are abnormal levels or activity of substances found in living
tissue that indicate exposure to toxicants and susceptibility to disease.
We study certain enzymes and chemical compounds to determine their usefulness
as biomarkers of toxic exposure. Our focus is on links between enzyme
levels, chemical exposure and genetic predisposition to toxic effects
of metals, pesticides and other chemicals.
Assess Physiological Damage
We investigate the complex interplay between low-level toxic exposure
and disease, genetic susceptibility factors and models for risk assessment.
Our studies seek to generate new scientific and health knowledge, and
create risk assessments and a framework for including wildlife assessments
in waste site evaluations and remediation decision-making.
Develop New Technology
We conduct research on biomarkers and physiological
damage associated with toxic exposure to support the development of new
technology to remediate contaminated sites. Technological research works
to develop a repertoire of plants that remediate toxic solvent spills,
broaden the range of compounds detoxified by plants, and further the knowledge
of microbial processes and their use in neutralizing contaminants.