James S. Woods
Director, Project 2
Heme pathway polymorphisms in mercury
neurotoxicity in adults and children

Contact

Phone: 206 685-3443
Fax: 206 685-4696
E-mail: jwoods@u.washington.edu

Mailing Address:
University of Washington
Box 354695
4225 Roosevelt Way NE, Suite 100
Seattle, WA 98105

Research Interests

Molecular mechanisms of metal toxicity
Porphyrins as biomarkers of metal exposure and toxicity
Genetic factors that modify risks of metal toxicity in humans

Recent publications

Woods JS, Martin MD, Leroux BG, DeRouen TA, Bernardo MF, Luis HS and Leitão JG, Simmonds PL, Kusleika JV and Huang Y. The contribution of dental amalgam to urinary mercury excretion in children. Environ. Health Perspect. 2007. (in press).

Echeverria D., Woods JS, Heyer NJ, Rholman D., Farin FM, Bittner AC, Li T
and Garabedian C. The association between a genetic polymorphism of coproporphyrinogen oxidase, dental mercury exposure and neurobehavioral response in humans. Neurotox Teratol. 2006; 28:39-48.

Heyer N, Bittner AC, Jr., Echeverria D and Woods JS. A cascade analysis of the interaction of mercury and coproporphyrinogen oxidase (CPOX) polymorphism on the heme biosynthetic pathway and porphyrin production. Toxicol Letts 2006; 161:159-166.

Woods JS, Echeverria D, Heyer NJ, Simmonds PL, Wilkerson J and Farin FM. The association between genetic polymorphisms of coproporphyrinogen oxidase and an atypical porphyrinogenic response to mercury exposure in humans. Toxicol. Appl. Pharmacol. 2005; 126:113-120.