SRP Publications & Presentations
READCriswell S, Perlmutter J, Huang J, Golchin N, flores H, Hobson A, Aschner M, Erikson K, Checkoway H, Racette B. Basal ganglia intensity indices and diffusion weighted imaging inmanganese exposed welders. Occup Environ Med. 2012. March 23 [epub ahead of print]
READ Nielsen SS, Gallagher LG, Lundin JL, Longstreth WT, Powers KM, Smith-weller T, Franklin GM, Swanson PD, Checkoway H. Environmental tobacco smoke and Parkinson disease. Mov Disord 2012;27:293-297.
READ Lee KY, Strand SE, and Doty SL. 2012. Phytoremediation of chlorpyrifos by Populus and Salix. International Journal of Phytoremediation 14(1):48-61.
READ Doty, SL and Lee KY. Eco-Friendly Plants at Work. Seattle Expanding Your Horizons Conference, Bellevue, WA, March 2012.
READ Harris RC, Lundin JI, Criswell SR, Hobson A, Swisher LM, Evanoff BA, Checkoway H, Racette BA. Effects of parkinsonism on health status in welding exposed workers. 2011 Nov; 17(9):672-6.
READ Criswell SR, Perlmutter JS, Videen TO, Moerlein SM, Flores HP, Birke AM, Racette BA. 2011. Reduced Uptake of [18F]FDOPA PET in Asymptomatic Welders with Occupational Manganese Exposure. Neurolog. 2011 Apr 12;76(15):1296-301.
Dhanker, O.P., Pilon-Smits, E., Meagher, R., and Doty, SL 2011. "Chapter 20: Biotechnological Approaches to Phytoremediation" In Plant Biotechnology and Agriculture: Prospects for the 21st Century. A. Altman and M. Hasegawa, eds. Elsevier.
READ Tilton F, Tilton S, Stapleton P, Bammler T, Beyer R, Scholz N, Gallagher E. 2011. Transcriptional impact on organophosphate and metal mixtures on olfaction: Copper dominates the chlorpyrifos-induced response in adult zebrafish. Aquatic Toxicology. 2011 Apr;102(3-4):205-15.
READ Tilton F, Bammler T, Gallagher E. 2011. Effect of copper and chlorpyrifos alone, and as mixtures, on zebrafish behavior. Comp. Biochem. Physiol. Part C. 153(1):9-16.
READ Lavado R and Schlenk D. 2011 Microsomal biotransformation of chlorpyrifos, parathion and fenthion in rainbow trout (Oncorhynchus mykiss) and coho salmon (Onchorynchus kisutch): Mechanistic insights into interspecific differences in toxicty. Aquatic Toxicol. 101:57-63.
READ Lavado R, Maryoung K, and Schlenk D. 2011. Hypersalinity Acclimation Increases the Toxicity of the Insecticide Phorate in Coho Salmon (Onchorynchus kisutch). Envr Sci and Technol. 45:4623-4629.
Cook TJ, Armaly JS, Osbun JW, Shi M, Racette BA, Checkoway H, Zhang J. α-Synuclein and DJ-1 in whole blood as biomarkers of parkinsonism. Presented at the Superfund Research Program Annual Conference, Lexington, KY, October, 2011.
Lundin JI, Checkoway H, Criswell S, Hobson A, Seixas N, Evanoff B, Sheppard L, Racette B. Parkisonism among workers from welding job sites. Presented at the Superfund Research Program Annual Conference, Lexington, KY, October, 2011.
Checkoway H. Are there any consistent environmental risk factors for Parkison disease? (Invited keynote talk.) EPICOH Conference, Oxford, UK, September, 2011.
Criswell S, Perlmutter J, Golchin N, Flores H, Hobson A, Aschner, Erickson K, Checkoway H, Racette B. Basal ganglia intensity in manganese-exposed welders. Presented at EPICOH Conference, Oxford, UK, September, 2011.
Lundin JI, Checkoway H, Criswell S, Hobson A, Seixas N, Evanoff B, Sheppard L, Racette B. Increased risk of parkinsonism associated with cumulative hours of welding. Presented at EPICOH Conference, Oxford, UK, September, 2011.
READ Searles Nielsen S, Gallagher LG, Lundin JI, Longstreth WT Jr, Farin FM, Smith-Weller T, Franklin GM, Swanson PD, Checkoway H. Genotype and Age at Parkinson Disease Diagnosis in a Health Maintenance Organization. World Federation of Neurology Neuroepidemiology Research Group meeting abstract. Neuroepidemiology 2011;36:134-140. (Also presented in Honolulu, Hawaii, April 2011)
Lundin JI, Checkoway H, Criswell S, Hobson A, Seixas N, Evanoff B, Sheppard L, Racette B. Increased risk of parkinsonism among welders. The 10th International Conference on Alzheimer's & Parkinson's Diseases. Barcelona, Spain, March 2011.
READ Montine TJ, Shi M, Quinn JF, Peskind ER, Craft S, Ginghina C, Chung KA, Kim H, Galasko DR, Jankovic J, Zabetian CP, Leverenz JB, Zhang J. CSF Abeta(42) and tau in Parkinson's disease with cognitive impairment. Mov Disord. 2010 Sep 3.
READ Shi M, Zabetian CP, Hancock AM, Ginghina C, Hong Z, Yearout D, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Leverenz JB, Zhang J. Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease. Neurosci Lett. 2010 Aug 9;480(1):78-82. Epub 2010 Jun 9.
READ Hofmann JN, Checkoway H , Borges O, Servic F, Fenske RA, Keifer MC. Development of a computer-based survey instrument for organophosphate and N-methyl-carbamate exposure assessment among agricultural pesticide handlers. Ann Occup Hyg 2010 Aug;54:640-650.
READ Kang, J. W., Wilkerson, H-W, Farin, F.M., Bammler, T.K., Beyer, R.P., Strand, S. E., and Doty, S.L. Mammalian cytochrome CYP2E1 triggered differential gene regulation in response to trichloroethylene (TCE) in transgenic poplar. Functional & Integrative Genomics 2010 Aug; 10(3):417-424.
READ Caudle WM, Bammler TK, Lin Y, Pan S, Zhang J. Using 'omics' to define pathogenesis and biomarkers of Parkinson's disease. Expert Rev Neurother. 2010 June;10(6):925-42.
READ Hofmann JN, Keifer MC, De Roos AJ, Fenske RA, Furlong CE, van Belle G, Checkoway H. Occupational determinants of serum cholinesterase inhibition among organophosphate-exposed agricultural pesticide handlers in Washington state. Occup Environ Med 2010 Jun;67:375-386.
READ Shi M, huber BR, Zhang J. Biomarkers for cognitive impairment in Parkinson disease. Brain Pathol. 2010 May;20(3):660-71
READ Hong Z, Shi M, Chung KA, Quinn JF, Peskind ER, Galasko D, Jankovic J, Zabetian CP, Leverenz JB, Baird G, Montine TJ, Hancock AM, Hwang H, Pan C, Bradner J, Kang UJ, Jensen PH, Zhang J. DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain. 2010 Mar;133(Pt 3):713-26. Epub 2010 Feb 15.
READ Firestone JA, Powers KM, Smith-Weller T, Franklin GM, Swanson PD, Longstreth WT Jr, Checkoway H. Occupational risk factors for Parkinson’s disease: a population-based case-control study. Am J Ind Med 2010 Mar;53:217-223.
READ Dhanker, O.P., Pilon-Smits, E., Meagher, R., and Doty, S.L. (in press) "Biotechnological Approaches to Phytoremediation" in Plant Biotechnology and Agriculture: Prospects for the 21st Century. A. Altman and M. Hasegawa, eds. Elsevier.
READ Browne. E, Kelly, M. Zhou, G.D., He, L.Y., McDonald, T., Wang, S., Duncan, B., Meador, J., Donelly, K., and Gallagher E. 2010. In situ biomonitoring of juvenile Chinook salmon (Onchorhynchus tshawytscha) using biomarkers of chemical exposures and effects in an urbanized waterway of the Puget Sound, WA. Environmental Research. 110(7):675-83.
Sharon L. Doty. International Poplar Symposium. September 20-25, 2010. Orvieto, Italy. Keynote Lecture. "Phytoremediation of TCE, Explosives, and Pesticides using Poplar."
Battelle's 7th International Conference on Remediation of Chlorinated and Recalitrant Compounds. May 24-27, 2010. Monterey, CA. Platform speaker. "Phytoremediation of TCE and Explosives by Transgenic Aspen. " Sharon L. Doty, Jun Won Kang, Hui-Wen Wilkerson, Federico M. Farin, Theo Bammler, Richard P. Beyer, Neil Bruce, and Stuart E. Strand.
Lundin J, Checkoway H, Evanoff B, Racette B. Early detection of parkinsonism using a predictive self-administered questionnaire. Presented at the World Federation of Neurology Research Group on Neuroepidemiology, Toronto, Canada, April, 2010 (Neuroepidemiology 2010;34:272).
Searles Nielsen S, Gallagher L, Lundin J, Zabetian C, Farin F, Longstreth WT, Smith-Weller T, Franklin G, Swanson P, Checkoway H. D1 dopamine receptor polymorphism and smoking: differential effect in Parkinson’s disease. Presented at the World Federation of Neurology Research Group on Neuroepidemiology, Toronto, Canada, April, 2010 (Neuroepidemiology 2010;34:272).
Harris R, Lundin JI, Criswell S, Hobson A, Swisher L, Evanoff B, Checkoway H, Racette B. Effects of parkinsonism on health status in welding exposed workers. Presented at the Epidemiology in Occupational Health Conference, Taipei, Taiwan, April, 2010.
Harvey Checkoway. Invited Seminar: “Environmental and Genetic Risk Factors for Parkinson’s Disease”, Tel Aviv University, Department of Neurology, Sackler School of Medicine, March, 2010.
Harvey Checkoway. Invited Seminar: “Environmental and Genetic Risk Factors for Parkinson’s Disease”, University of California, San Diego, Department of Community and Family Medicine, La Jolla, CA, January, 2010.
READ James, C. A., Xin, G., Doty, S. L., Muiznieks, I., Newman, L. A., and Strand, S. E. A Mass Balance Study of the Phytoremediation of Perchloroethylene-Contaminated Groundwater. Environmental Pollution. Environ Pollut 2009 Aug-Sep;157(8-9):2564-9.
READ Hofmann JN, Furlong CE, Farin FM, et al. Serum cholinesterase inhibition in relation to paraoxonase (PON1) status among organophosphate-exposed agricultural pesticide handlers. EHP 2009 2009 Sep;117(9):1402-8.
READ Hobson A, Sterling DA, Emo B, Evanoff B, Sterling C, Good L, Seixas N, Checkoway H, Racette B. Validity and reliability of an occupational exposure questionnaire for parkinsonism in welders. J Occup Environ Health 2009;6 (6):324-331.
READ James, C. A., and Strand, S. E. Phytoremediation of Small Organic Contaminants Using Transgenic Plants. Current Opinion in Biotechnology. Curr Opin Biotechnol 2009 Apr;20(2):237-41.
READ Giordano G, Li L, White CC, Farin FM, Wilkerson HW, Kavanagh TJ, Costa LG. Muscarinic receptors prevent oxidative stress-mediated apoptosis induced by domoic acid in mouse cerebellar granule cells. J Neurochem. 2009 Apr;109(2):525-38.
READ Lefebvre KA, Bammler TK, Farin FM, Gallagher EP, et al. Gene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and asymptomatic doses. Tox Sci 2009 Jan;107(1):65-77.
READ Heyer NJ, Farin FM, Woods JS, et al. COMT Val158Met Functional Polymorphism, Dental Mercury Exposure, and Self-reported Symptoms and Mood. J Toxicol Environ Health A. 2009;72(9):599-609.
Harris RC, Lundin JI, Criswell SR, Good LM, Sterling C, Evanoff BA, Checkoway H, Racette BA. Effects of parkinsonism on quality of life in welding exposed shipyard workers. International Congress of Parkinson's Disease and Movement Disorders, June 2009.
Gallagher, E.P. Using comparative genomics to understand mechanisms of olfactory injury in Pacific salmon. Physiological Responses in Marine Organisms (PRIMO 15). Bordeaux, France, May 17-20, 2009.
READ Sharon Doty. Eco-Friendly Plants at Work. Expanding Your Horizons Conference, presented by the American Association of University Women to encourage girls to enter fields of science and math. Bellevue Community College, March 25, 2009.
Keum Young Lee, Sharon L. Doty, and Stuart E. Strand. Phytoremediation of Chlorpyrifos by Populus and Salix. The 81st Annual Northwest Scientific Association Meeting. Participant in poster session, Seattle, WA, Mar. 25~28, 2009
Keum Young Lee, Sharon L. Doty, and Stuart E. Strand. Phytoremediation of Chlorpyrifos by Populus and Salix, The 6th Annual College of Forest Resources Graduate Student Symposium, Participant in poster and oral session, University of Washington, Seattle, WA, Mar. 06, 2009
Jun Won Kang, Sharon Doty. Genetic analysis of Trichloroethylene (TCE) metabolism in hybrid poplar and transgenic poplar. Western - American Society of Plant Biologists. Tuscon, AZ, April 25-26, 2009.
READ Costa LG, Cole TB, Jansen, KL, Furlong CE. 2008. Paraoxonase (PON1) and organophosphate toxicity. In: The Paraoxonases: Their Role In Disease, Development And Xenobiotic Metabolism, B Mackness, M Mackness, M Aviram and G Paragh eds. Springer, Dordrecht, The Netherlands, pp. 209-220
READ Costa-Mallen P, Checkoway H, Zabetian C, et al. 2008. The functional polymorphism of the hemoglobin-binding haptoglobin influences susceptibility to Parkinson’s disease. Am J Med Genet (B);147:216-222.
READ Furlong CE, Richter RJ, Li W-F, Brophy VH, Carlson C, Meider M, Nickerson D, Costa LG, Ranchalis J, Lusis AJ, Shih DM, Tward A, Jarvik GP. 2008. The functional consequences of polymorphisms in the human PON1 gene. In: The Paraoxonases: Their Role In Disease, Development And Xenobiotic Metabolism, B Mackness, M Mackness, M Aviram and G Paragh eds. Springer, Dordrecht, The Netherlands, pp. 267-281
READ Furlong CE. 2008. The Bert La Du Memorial Lecture: Paraoxonases: an historical perspective. In: The Paraoxonases: Their Role In Disease, Development And Xenobiotic Metabolism, B Mackness, M Mackness, M Aviram and G Paragh eds. Springer, Dordrecht, The Netherlands, pp. 3-31.
READ Gallagher, E., LaVire, H., Stapleton, P., Bammler, T, Beyer, D., and F. Farin. 2008. Expression profiling of hepatic genes in smolting and adult coho salmon (Onchorhynchus kisutch). Environmental Research. Mar;106(3):365-78
READ James, C. A., Xin, G., Doty, S. L., and Strand. S. E.. 2008. A Comparison of the Degradation of Low Molecular Weight Volatile Organic Compounds by Plants: the Effects of Transgenic Modification with Mammalian Cytochrome P450 2E1. Environ Sci & Technol. Jan 1;42(1):289-93
READ Martin MD, Woods JS, Leroux BG, Rue T, DeRouen TA, Leitão, JG, Luis HS and Kushleika JV. 2008. Longitudinal urinary creatinine excretion values among children. Translat. Res. 151:51-56.
READ Matsuo, A., Li, Q., Gallagher, E., Trute, M., Janssen, P. and D.R Schlenk. 2008. Characterization of liver phase I biotransformation enzymes in coho salmon. Comp Biochem Physiol C. Jan;147(1):78-84
READ McIntyre, J., Baldwin, D.H., Meador, J.P., and Scholz, N.L. 2008. Chemosensory deprivation in juvenile coho salmon exposed to dissolved copper under varying water chemistry conditions. Environmental Science and Technology. Feb 15;42(4):1352-8
READ Powers KM, Smith-Weller T, Franklin GM, Longstreth WT, Jr., Swanson PD, Checkoway H. 2008. Dietary fats, cholesterol and iron as risk factors for Parkinson’s disease. Parkinson Relat Disord Apr 17
Hobson A, Sterling D, Evanoff B, Racette B. Validity and reliability of an Occupational Exposure Questionnaire for Parkinsonsim in Welders. American Industrial hygine Conference and Exposition. Minneapolis, MN, May 31- June 5, 2008.
Costa LG. 2007. Toxic effects of pesticides. IN: Casarett and Doull’s Toxicology. The Basic Science of Poisons. 7th Edition. CD Klaassen ed. McGraw-Hill, New York, NY
READ Doty SL, James CA, Moore AL, Vajzovic A, Singleton GL, Ma C, Khan Z, Xin G, Kang JW, Park JY, Meilan R, Strauss SH, Wilkerson J, Farin F, Strand SE. 2007. Enhanced phytoremediation of volatile environmental pollutants with transgenic trees. Proc Natl Acad Sci U S A. Oct 23;104(43):16816-21.
READ Furlong CE. 2007 Genetic variability in the cytochromes P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds. J Biochem Mol Toxicol 21:197- 205.
READ Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG. 2007. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicol Appl Pharmacol ; 219: 181-189.
READ Heyer N, Bittner AC, Jr., Echeverria D and Woods JS. 2007. Response to comment on: “ A cascade analysis of the interaction of mercury and coproporphyrinogen oxidase (CPOX) polymorphism on the heme biosynthetic pathway and porphyrin production” by Heyer et al. [Toxicol Letts 2006; 161:159-166]. Toxicol. Letts. 169:93-94.
READ Martin MD, Benton T, Bernado M, Woods JS, Townes BD, Luis H, Leitão J, Rosenbaum G, Castro-Caldas A, Pavao I, Rue T and DeRouen TA. 2007. The association between dental caries with blood lead in children when adjusted for IQ and neurobehavioral performance. Sci. Tot. Environ. 377:159-164.
READ Polk WW, Ellis ME, Kushleika JV, Simmonds PL and Woods JS. 2007. RhoA regulation of NF-kappaB activation is mediated by Cox-2 dependent feedback inhibition of IKK in kidney epithelial cells. Amer. J. Physiol.-Cell Physiol. 93(3):C1160-1170.
READ Ritz B, Ascherio A, Checkoway H, Marder KS, Nelson LM, Rocca WA, Ross GW, Strickland D, Van Den Eeden SK, Gorell J. 2007. Pooled analysis of tobacco use and Parkinson’s disease. Arch Neurol; 64:990-997.
READ Ton TG, Heckbert SR, Longstreth WT, Rosssing MA, Kukull WA. Franklin GM, Swanson PD, Smith-Weller T, Checkoway H. 2007. Calcium channel blockers and beta-blockers in relation to Parkinson’s disease. Parkinsonism Relat Disord ;13:165-169.
READ Trute, M., Gallus, B., Goodlett, D. and Gallagher, E.P. 2007. Glutathione S-transferase isozyme expression in coho salmon liver. Aquatic Toxicology. 81:126-136.
READ Woods JS, Martin MD, Leroux BG, DeRouen TA, Bernardo MF, Luis HS and Leitão JG, Simmonds PL, Kushleika JV and Huang Y. 2007. The contribution of dental amalgam to urinary mercury excretion in children. Environ. Health Perspect. 115:1527-1531.
READ Carlson CS, Heagerty PJ, Hatsukami TS, Richter RJ, Ranchalis J, Lewis J, Bacus TJ, McKinstry LA, Schellenberg GD, Rieder M, Nickerson D, Furlong CE, Chait A, Jarvik GP. 2006. TagSNP analyses of the PON gene cluster: effects on PON1 activity, LDL oxidative susceptibility, and vascular disease. J Lipid Res 47(5):1014-24.
Costa LG, Cole TB, Furlong CE. 2006. Gene-environment interactions: paraoxonase (PON1) and sensitivity to organophosphate toxicity. Lab Med ; 37: 1-5.
READ Costa LG. 2006. Current issues in organophosphate toxicology. Clin. Chim. Acta 2006; 366:1-13.
Costa LG, Cole TB, Vitalone A, Furlong CE. Paraoxonase polymorphisms and toxicity of organophosphates. IN: Toxicology of Organophosphate and Carbamate Pesticides. RC Gupta ed. Elsevier, Burlington, MA; pp. 247-256.
Costa LG, Cole TB, Geiss GK and Furlong CE. 2006. Chapter 8. Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. Costa LG and Eaton, DL, Gene-Environment Interactions: Fundamentals of Ecogenetics, John Wiley & Sons, Hoboken, NJ.
READ Furlong C, Holland N, Richter R, Bradman A, Ho A, and B Eskenazi. 2006. PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. Pharmacogenetics and Genomics. 16:183-190.
READ Kelada SNP, Checkoway H, Kardia LR, et al. 2006. 5’ and 3’ Region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson’s disease risk: a hypothesis generating study. Hum Molec Genet; 15:3055-3062.
READ Maraganore DM, de Andrade M, Elbaz A, Farrer M, Ionnidis JP, Kruger R, Rocca WA, Schneider NK, Lesnick TG, Lincoln SJ, Hulihan MM, Aasly JO, Ashizawa T, Chartier-Harlin MC, Checkoway H, et al. 2006. Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson’s disease. JAMA; 296:661-670.
READ Martin MD and Woods JS. 2006. The safety of dental amalgam in children. Expert Opin. Drug Safety. 5:773-781.
READ Powers KM, Smith-Weller T, Franklin GM, Longstreth WT Jr., Swanson PD, Checkoway H. 2006. Reduced risk of Parkinson’s disease among diabetics. Parkinson Relat Disord.;12:185-189.
READ Ton TG, Heckbert SR, Kukull WA, Longstreth WT Jr., Franklin GM, Swanson PD, Smith-Weller T, Checkoway H. 2006. Aspirin, other non-steroidal anti-inflammatory drugs, and risk of Parkinson’s disease. Mov Disord;21:964-969.