Project 1: SRP Publications & Presentations
Paraoxonases: Biomarkers of Susceptibility to Environmentally-induced Diseases

2010
Publications

READ Hofmann JN, Keifer MC, De Roos AJ, Fenske RA, Furlong CE, van Belle G, Checkoway H. Occupational determinants of serum cholinesterase inhibition among organophosphate-exposed agricultural pesticide handlers in Washington state. Occup Environ Med 2010 Jun;67:375-386.

2009
Publications

READ Hofmann JN, Furlong CE, Farin FM, et al. Serum cholinesterase inhibition in relation to paraoxonase (PON1) status among organophosphate-exposed agricultural pesticide handlers. EHP 2009 2009 Sep;117(9):1402-8.

2008
Publications

READ Costa LG, Cole TB, Jansen, KL, Furlong CE. 2008. Paraoxonase (PON1) and organophosphate toxicity. In: The Paraoxonases: Their Role In Disease, Development And Xenobiotic Metabolism, B Mackness, M Mackness, M Aviram and G Paragh eds. Springer, Dordrecht, The Netherlands, pp. 209-220

READ Furlong CE, Richter RJ, Li W-F, Brophy VH, Carlson C, Meider M, Nickerson D, Costa LG, Ranchalis J, Lusis AJ, Shih DM, Tward A, Jarvik GP. 2008. The functional consequences of polymorphisms in the human PON1 gene. In: The Paraoxonases: Their Role In Disease, Development And Xenobiotic Metabolism, B Mackness, M Mackness, M Aviram and G Paragh eds. Springer, Dordrecht, The Netherlands, pp. 267-281

READ Furlong CE. 2008. The Bert La Du Memorial Lecture: Paraoxonases: an historical perspective. In: The Paraoxonases: Their Role In Disease, Development And Xenobiotic Metabolism, B Mackness, M Mackness, M Aviram and G Paragh eds. Springer, Dordrecht, The Netherlands, pp. 3-31.

2007
Publications

Costa LG. 2007. Toxic effects of pesticides. IN: Casarett and Doull’s Toxicology. The Basic Science of Poisons. 7th Edition. CD Klaassen ed. McGraw-Hill, New York, NY

READ Furlong CE. 2007 Genetic variability in the cytochromes P450-paraoxonase 1 (PON1) pathway for detoxication of organophosphorus compounds. J Biochem Mol Toxicol 21:197- 205.

READ Giordano G, Afsharinejad Z, Guizzetti M, Vitalone A, Kavanagh TJ, Costa LG. 2007. Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency. Toxicol Appl Pharmacol ; 219: 181-189.

2006
Publications

READ Carlson CS, Heagerty PJ, Hatsukami TS, Richter RJ, Ranchalis J, Lewis J, Bacus TJ, McKinstry LA, Schellenberg GD, Rieder M, Nickerson D, Furlong CE, Chait A, Jarvik GP. 2006. TagSNP analyses of the PON gene cluster: effects on PON1 activity, LDL oxidative susceptibility, and vascular disease. J Lipid Res 47(5):1014-24.

Costa LG, Cole TB, Furlong CE. 2006. Gene-environment interactions: paraoxonase (PON1) and sensitivity to organophosphate toxicity. Lab Med ; 37: 1-5.

READ Costa LG. 2006. Current issues in organophosphate toxicology. Clin. Chim. Acta 2006; 366:1-13.

Costa LG, Cole TB, Vitalone A, Furlong CE. Paraoxonase polymorphisms and toxicity of organophosphates. IN: Toxicology of Organophosphate and Carbamate Pesticides. RC Gupta ed. Elsevier, Burlington, MA; pp. 247-256.

Costa LG, Cole TB, Geiss GK and Furlong CE. 2006. Chapter 8. Paraoxonase, butyrylcholinesterase, and epoxide hydrolase. Costa LG and Eaton, DL, Gene-Environment Interactions: Fundamentals of Ecogenetics, John Wiley & Sons, Hoboken, NJ.

READ Furlong C, Holland N, Richter R, Bradman A, Ho A, and B Eskenazi. 2006. PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity. Pharmacogenetics and Genomics. 16:183-190.