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Triplet Repeat Journal Club

Schedule of Presenters

Meets every three weeks on Fridays at noon in G-328

December 3, 2010

Catherine Konopka

Native functions of the androgen receptor are essential to pathogenesis in a drosophila model of spinobulbar muscular atrophy.
N.B. Nedelsky….J.P. Taylor. Neuron 67:936–52, 2010.

November 12, 2010

Suman Jayadev

High insulinlike growth factor I is associated with cognitive decline in Huntington disease.
Saleh N….Huntington French Speaking Group. Neurology 75:57-63, 2010.

October 22, 2010

Eric Horne

Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into Huntington’s disease molecular pathogenesis.
J. Miller….S. Finkbeiner. J Neurosci 30:10541-50, 2010.

October 1, 2010

Alipi Naydenov

A two-step path to inclusion formation of huntingtin peptides revealed by number and brightness analysis.
G. Ossato….E. Gratton. Biophys J 98:3078-85, 2010.

September 10, 2010

Rich Gardner

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS.
A.C. Elden....A.D. Gitler. Nature 466:1069-77, 2010.

August 20, 2010

Gwenn Garden

Modulation of energy deficiency in Huntington’s disease via activation of the peroxisome proliferator-activated receptor gamma.
M.C. Chiang….Y. Chern. Hum Mol Genet, August 6, 2010 (Epub ahead of print).

July 30, 2010

Nephi Stella

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin.
S. Okamoto….S.A. Lipton. Nature Med 15:1407-13, 2009.

July 9, 2010

Eric Horne

Cargo recognition failure is responsible for inefficient autophagy in Huntington’s disease.
M. Martinez-Vicente....A.M. Cuervo. Nature Neurosci 13:567-78, 2010.

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Updated 11/29/2010