Wei Li, M.D., Ph.D.
Academic Office:Phone: (206) 616-9120 E-mail: Fax: (206) 616-0612 Address: |
Research Assistant Professor
Faculty Appointments:
University of Washington, Research Assistant Professor, 2003 - present.
University of Pittsburgh, Research Instructor, 1998-2001.
Education:
Fellowships: Research Fellow, Thomas E. Starzl Transplantation Institute, University of Pittsburgh, 1994-1997. Senior Transplant Fellow, University of Washington, 2001-2003.
Ph.D.: Medicine, Transplant Immunology, JiLin University Norman Bethune Medical School, China, 1999.
M.S.: Medicine, Liver Surgery, JiLin University Norman Bethune Medical School, China, 1991.
Residency: Department of Surgery, Third Teaching Hospital, JiLin University Norman Bethune Medical School, 1985 - 1991.
M.D.: JiLin University Norman Bethune Medical
School, China, 1980 - 1985.
Research Interests:
- Mechanism of organ transplant tolerance and rejection — the role of regulatory T cells, dendritic cells, NK T cells, and costimulatory molecules on the regulation of peripheral tolerance.
- Approaches of novel immunosuppressive therapy in organ transplantation.
download Annual Research Report 
Selected Publications:
Li W, Fu F, Lu L, Narula SK, Fung JJ, Thomson AW, Qian S. Recipient pretreatment with cellular IL-10 prolongs cardiac allograft survival in mice. Transplantation, 68:1402, 1999.
Li W, Lu L, Wang Z, Wang L, Fung JJ, Thomson AW, and Qian S. IL-12 antagonism enhances apoptotic death of T cells within hepatic allografts from Flt3-treated donors and promotes the restoration of transplant tolerance. J Immunology, 166:5619-5628, 2001.
Li W, Lu L, Wang Z, Wang Z, Fung JJ, Thomson AW, and Qian S. Costimulation blockade promotes the apoptotic death of graft infiltrating T cells and prolongs survival of hepatic allografts from Flt3L-treated donors. Transplantation, 72:1423-1432, 2001.
Li W, Chou S, Wang C, Kuhr C, Perkins J. The role of the liver in peripheral tolerance: Induction through oral antigen feeding. Am J Transplantation, 4:1574-1582, 2004.
Li W, Zheng XX, Kuhr CS, Perkins JD. CTLA4 engagement is required for induction of murine liver transplant spontaneous tolerance. Am J Transplantation, 5:978-986, 2005.
Li W, Carper K, Perkins JD. Enhancement of NKT cells and increase in regulatory T cells results in improved allograft survival. J Surg Res, 134:10-21, 2006.
Li W, Carper K, Liang Y, Zheng XX, Kuhr CS, Reyes JD, Perkins DL, Thomson AW, Perkins JD. The role of Foxp3 regulatory T cells in liver transplant tolerance. Transplant Proc, 38:3205-3206, 2006.
reviewed 2/07