James O. Park, M.D.
Patient Services:University of Washington Medical Center Patient Scheduling: Academic Office:Phone: (206) 685-4672 E-mail: jopark@u.washington.edu Fax: (206) 543-8136 Address: |
Assistant Professor
Faculty Appointment:
University of Washington, Assistant Professor, 2007 - present.
Education:
Fellowships: Research Fellowship, Oncology, University of Chicago, 2000 - 2002.
Surgical Oncology, Memorial Sloan Kettering Cancer Center, 2005 - 2007.
Residency: University of Chicago, 1998 - 2000, 2002 - 2005.
M.D. Degree: University of Pennsylvania, 1998.
Board Certified: General Surgery, American Board of Surgery, 2006.
Clinical Interests:
Surgical Oncology: Multidisciplinary management of neoplasms of the liver, biliary tract, pancreas, and upper gastrointestinal tract. Minimally invasive liver and pancreatic surgery and radiofrequency ablation.
Research Interests:
Translational application of nanotechnology in the treatment of unresectable liver malignancies refractory to conventional therapy.
Selected Publications:
Khodarev NN, Park JO, Yu J, Gupta N, Nodzenski E, Roizman B, Weichselbaum RR. Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts. Proc Natl Acad Sci USA, 2001 Oct 23;98(22):12665-70.
Gupta VK, Park JO, Jaskowiak NT, Mauceri HJ, Seetharam S, Weichselbaum RR, Posner MC. Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma. Ann Surg Oncol. 2002 Jun;9(5):500-4.
Park JO, Lopez CA, Gupta VK, Brown CK, Mauceri HJ, Darga TE, Manan A, Hellman S, Posner MC, Kufe DW, Weichselbaum RR. Transcriptional control of viral gene therapy by cisplatin. J Clin Invest. 2002 Aug;110(3):403-10.
Khodarev NN, Park J, Kataoka Y, Nodzenski E, Hellman S, Roizman B, Weichselbaum RR, Pelizzari CA. Receiver operating characteristic analysis: a general tool for DNA array data filtration and performance estimation. Genomics. 2003 Feb;81(2):202-9.
Gupta VK, Park JO, Kurihara T, Koons A, Mauceri HJ, Jaskowiak NT, Kufe DW, Weichselbaum RR, Posner MC. Selective gene expression using a DF3/MUC1 promoter in a human esophageal adenocarcinoma model. Gene Ther. 2003 Feb;10(3):206-12.
Lopez CA, Kimchi ET, Mauceri HJ, Park JO, Mehta N, Murphy KT, Beckett MA, Hellman S, Posner MC, Kufe DW, Weichselbaum RR. Chemo-inducible gene therapy: A strategy to enhance doxorubicin anti-tumor activity. Mol Cancer Ther. 2004 Sep;3(9):1167-75.
Kimchi ET, Posner MC, Park JO, Darga TE, Kocherginsky M, Karrison T, Hart J, Smith KD, Mezhir JJ, Weichselbaum RR, Khodarev NN. Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation. Cancer Res. 2005 Apr 15;65(8):3146-54.
Park JO, Gonen M, D’Angelica M, DeMatteo RP, Fong Y, Wuest D, Blumgart LH, Jarnagin WR. Autologous versus allogeneic transfusions: No difference in peri-operative outcome after partial hepatectomy. J Gastrointest Surg. 2007 Jul 31; Epub ahead of print.
reviewed 9/07